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What is Nyvepria?

Nyvepria can be used to treat neutropenia (a shortage of white blood cells in certain cases), which is caused by chemotherapy. Nyvepria is a protein that helps stimulate the development of cells called white blood cells. These cells aid your body in fighting infections. Nyvepria can also be used to treat conditions that are not covered in this medication guide.

Side effects of Nyvepria:  

Seek medical attention immediately. If you are experiencing symptoms that are warning signs of an allergic reaction, such as itchy facial eruptions, sweating or tingling, dizziness, quick heartbeats, wheezing or breathing difficulties, or swelling of your lips, face, and tongue,

The condition is known as capillary leak syndrome, which can occur as a very rare but very serious consequence caused by pegfilgrastim. Contact your physician immediately if you are experiencing symptoms of this disorder, which could include a decrease in urinary frequency, fatigue, dizziness, lightheadedness, faintness, or trouble breathing. You may also experience abrupt swelling, puffiness, or feeling full.

Nyvepria can cause severe adverse effects. Consult your physician immediately if you suffer from:

  • A sudden and severe pain is felt in the left upper abdomen, spreading all the way to your shoulder

  • Abrupt and intense pain in your chest, stomach, or back;

  • Chronic or persistent pain in your body.

  • Fever, tiredness;

  • Breathlessness and rapid breathing.

  • Simple bleeding, unusual red or purple spots on the skin

  • Swelling, bruising, or a hard lump in the area where the medicine was injected,

  • Kidney issues: no or little urinary tract infections; dark or pink urine; swelling on your legs, face, or around your ankles.

The cancer treatments could be delayed or completely stopped when you experience certain negative side effects.

Common adverse effects of Nyvepria could include:

  • Bone pain 

  • The pain in your arms and legs.

This isn't a complete list of all the side effects. Other side effects could be present. Consult your physician for advice regarding medical adverse effects. You can report any side effects to the FDA at 1-800-FDA-1088.


Follow the directions on your prescription label and on the label of your package. Be sure to inform your health care providers about your medical issues, allergies, and the medicines you are taking. 

Prior to use this drug 

It is not recommended to use Nyvepria if you are allergic to Nyvepria or filgrastim (Neupogen). Speak to your doctor if you are ever diagnosed with:

  • Sickle cell disorder;

  • Kidney disease;

  • Acute myeloidleukemia

  • Radiation treatment;

  • Myelodysplastic disease (also referred to as "preleukemia"); 

  • An allergy to latex allergic reaction.

With treatment using Fulphila and radiation and the option of chemotherapy without or with lung cancer, there is a chance that you will be diagnosed with a blood disorder or an abnormality in your blood (leukemia). Talk to your doctor regarding this possibility. Inform your doctor if you are nursing or pregnant.

How to take Nyvepria?

Follow the instructions on your prescription label, and review all medication guides and instructions. Utilize the medicine according to the directions. Nyvepria is not to be administered within 14 days prior to or within 24 hours following the time you have received chemotherapy. Nyvepria is injected underneath the skin. A doctor may show you how to use the drug on your own. Be sure to read and adhere to any instructions for use that come with your medication. Talk to your pharmacist or doctor for clarification if you aren't sure about the instructions. You should prepare your injection only when you are ready to administer it. Don't use it when the medication appears cloudy, changes color, or contains particles. Contact your pharmacist to inquire about the latest medication. Your blood could require frequent testing.

Follow the directions of your physician before giving Nyvepria to children who have a weight of less than 99 lbs (45 kg). The correct dosage for a child of this size is not easily measured with the syringe that is prefilled. It is possible that you will require medical tests to aid your doctor in determining the best time frame to treat you with Nyvepria. Place the already-filled syringe in the original container inside the refrigerator, shielded from light. Do not shake or freeze.

Remove the syringe from the refrigerator and allow it to cool to around 30 minutes before injecting the dose. If the syringe is frozen, you can thaw it by placing it in the refrigerator. Don't use a syringe that has been frozen more than a few times. Don't utilize the Neulasta or Udenyca syringe that was kept at room temperature for more than 48 hours. Don't make use of any Fylnetra, Fulphila, or Stimufend syringe that has been stored on the counter at room temperature for more than 72 hours. Don't make use of any Zie


syringe that has been kept outside at room temperature for more than 5 days.

The Neulasta Onpro Injector is a device that is placed on the skin to deliver your Nyvepria dose at a certain time. It is necessary to keep the injector on for a period of 27 hours prior to when the dose will begin. The dose that you have scheduled will be removed slowly from the device over a 45-minute duration. Make sure to keep Neulasta Pro cool until you are able to put it on. Don't use a Neulasta Onpro device that has been left out of the refrigerator for more than 12 hours. Don't use a Nys Pre-filled syringe that has been stored in the refrigerator for more than 15 days.

When wearing Neulasta Onpro, the wearer or caregiver should examine the device to be sure that it's working correctly. The syringe or Onpro Injector is designed for one usage only. It is best to dispose of it after one use, regardless of whether there's still medicine within. Make use of the needle and the syringe once only and put them into the puncture-proof "sharps" container. Be sure to follow the laws of your state or city regarding how to dispose of the container. Keep it out of the reach of pets and children.

What happens if I miss the dose?

Contact your physician for advice when you have missed an injection or there is a problem with Neulasta Onpro. Neulasta Onpro machine.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help line toll-free at 1-800-222-1222.

Overdose symptoms can include bones hurting, pain when you breathe, feeling sluggish in a reclining position, and wheezing. You may also experience heavy breathing, a cough with foamy mucus, cold skin that is clammy, anxiety, and rapid heartbeats.

What should be avoided?

While using Neulasta Onpro Beware of travelling or driving machinery while wearing the device.

Interaction with other drugs

Other medications can influence Nyvepria, such as prescription and over-the-counter medicines, vitamins, and herbal products. Discuss with your physician the medicines you are currently taking and any medications you begin or stop taking.




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