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Generic name for rizatriptan: [RYE-zaTRIP-tan]
Brand names: Maxalt and
Drug class: antimigraine agents

What is Maxalt MLT?

Maxalt is a migraine medication that narrows blood vessels around your brain. This medicine reduces the substances in your body that trigger migraine symptoms, such as nausea and headache pain. Maxalt-MLT can be used to treat migraines. This medication will only treat headaches that have already started. This medicine will not reduce headaches or prevent them. Maxalt-MLT is not recommended for treating a tension headache or a headache causing loss of motion on one side. Only use Maxalt-MLT if a doctor has confirmed that your condition is migraine headaches.This medication guide does not list all possible uses of Maxalt-MLT.

Side effects of Maxalt-MLT

If you experience any of the following symptoms of an allergic reaction, seek immediate medical attention: hives, difficulty breathing, swelling of your lips, face, throat, or tongue.

Maxalt-MLT can cause serious side effects. If you experience:

  • diarrhea and sudden severe abdominal pain
  • Coldness or numbness of the feet and hands
  • A severe headache can cause blurred vision or pounding in the neck and ears.
  • heart attack symptoms: chest pain or pressure; pain spreading to the jaw or shoulder; nausea.
  • High levels of serotonin can cause agitation, fever, rapid heart rate, muscle stiffness, and twitching. Loss of coordination.
  • Signs of a stroke include sudden numbness and weakness, especially on one side; severe headaches; slurred or shaky speech; or problems with vision or equilibrium.

Maxalt-MLT can cause a variety of side effects.

  • Feeling tired, or feeling dizzy,
  • Pain or pressure in the chest or throat.

There may be other side effects. For medical advice on side effects, call your doctor. The FDA can be contacted at 1-800-FDA-1088 to report side effects.

Similar drugs

Nurtec ODT (Ubrelvy), diclofenac, celecoxib, sumatriptan, and metoclopramide


Maxalt-MLT should not be used if you suffer from uncontrolled hypertension or heart problems. You may also have a history of heart attacks, strokes, or circulation issues that result in a lack of blood supply.Take Maxalt-MLT at least 24 hours after taking another migraine headache medication.If you've taken an MAO-inhibitor in the last 14 days (such as isocarboxazid or linezolid), do not take this medication.

Before you take this drug

Maxalt-MLT should not be used if:

  • Heart problems or strokes (including "ministrokes")
  • coronary heart disease; angina; blood circulation problems; and lack of blood supply to your heart.
  • Uncontrolled high blood pressure
  • Severe liver disease
  • A headache that is different from the usual migraine headaches.

You should not take Maxalt-MLT if you've taken an MAO inhibitor within the last 14 days. Drug interactions may occur. MAO inhibitors are isocarboxazid (linezolid), methylene blue injection, phenelzine rasagiline, selegiline, tranylcypromine, and others.

Make sure you tell your doctor about those symptoms:

  • Liver or kidney disease
  • heart problems, chest pain;
  • Shortness of breath
  • Risk factors for coronary heart disease include high blood pressure, high cholesterol, diabetes, menopause, and smoking. Other risk factors are family history, obesity, age over 40, and being male.

Make sure to tell your doctor if you are also taking stimulant medicines, opioid medications, herbal supplements, or medication for mental illness, depression, or migraine headaches. Maxalt-MLT may cause serotonin disorder if these medicines are taken together.Phenylalanine may be present in Maxalt-MLT tablets. Inform your doctor if phenylketonuria is present.Inform your doctor if you are pregnant or nursing.Maxalt-MLT cannot be used by children younger than six years of age.

How to take Maxalt MLT?

Take Maxalt-MLT immediately if you experience headache symptoms. Please read the instructions on your prescription label. Follow the directions on the label. Your first dose may be administered in a hospital setting or clinic to treat any serious side effects.

Please read and follow all instructions for use that come with your medication. If you don't understand the instructions, ask your doctor or pharmacist. Only remove an oral disintegrating tablet when you're ready to use it. Place the tablet in your mouth without chewing. As the tablet dissolves, you should swallow it several times. After taking the tablet (for adults),

if your headache doesn't completely disappear or if it goes away then comes back again, take another tablet two hours after you took the first. Contact your doctor if your symptoms do not improve.If you have a headache after taking a tablet for children aged 6–17 and it does not go away completely, or if the headache goes away but then comes back again, consult your doctor.

Do not exceed the recommended dosage. The overuse of migraine headache medication can worsen headaches. If the medication seems to be less effective in treating migraine attacks, tell your doctor.if your symptoms don't improve or you experience more than four headaches within a month (30 days), call your doctor. Maxalt-MLT may cause dangerously high blood pressure. You may need to check your blood pressure frequently if you use Maxalt-MLT. You may need an ECG or electrocardiograph (also called an EKG) to check your heart function if you are using this medication long-term.Store away from heat and moisture at room temperature.

What happens if I miss the dose?

Maxalt-MLT does not require a schedule of daily dosages because it is only used as needed. If your symptoms don't improve after taking this medication, call your doctor.

What happens if I overdose?

Call 1-800-222-1222 for poison help or seek immediate medical attention.

What should be avoided?

Take Maxalt-MLT at least 24 hours after taking another migraine headache medication, such as:

  • Almotriptan (also known as eletriptan), frovatriptan (also known as naratriptan), sumatriptan, and zolmitriptan are all examples of this medication.
  • ergot medicine: dihydroergotamine, ergotamine, ergonovine, and methylergonovine.
    You should avoid driving or other hazardous activities until you are sure of how Maxalt-MLT affects you. You may be unable to react.

Interaction with other drugs.

Tell your doctor about all of your other medications.

  • propranolol;
  • Antidepressants; or
  • Medicine to treat a mental disorder.


This list is incomplete. Maxalt-MLT may be affected by other drugs, such as prescription and over-the-counter medicines, vitamins, and herbal products. This list does not include all possible drug interactions.Tell your doctor if you are taking any other medications, including antidepressants.Maxalt-MLT may be affected by other drugs, such as prescription and over-the-counter medicines, herbal products, vitamins, and herbal supplements. Inform your doctor of all the medicines you are currently taking and those that you will begin or stop using.