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Marcaine HCl

Name of the Generic: Bupivacaine “Bue-PIV-a-kane” bue-PIV-a-kane“bue-PIV-a”-kane.
Names of Brands: Marcaine HCl, Marcaine Spinal, Sensorcaine, and Sensorcaine-MPF.
Drug Class: Local injectable anesthetics.

What is Marcaine HCl?

Marcaine HClthat is an anesthetic (numbing medicine) which is utilized as a regional (in only one location) anesthetic. Marcaine HCl is administered by injection to the spinal column and causes the sensation of numbness in the labor process, surgery, or other treatments. Marcaine HCl may also be employed as an anesthetic in dental procedures. Marcaine HCl can also be used to treat conditions not mentioned in this medication guide.

Side effects of Marcaine HCl

Take immediate medical assistance. If you notice symptoms that are warning signs of an allergic reaction, such as the red, itchy rash, itching,sneezing, and breathing difficulties, You may also experience sneezing and severe dizziness, vomiting, and swelling of your lips, face, and tongue. Inform your healthcare providers immediately. If you suffer from one of the following serious negative side effects:

  • Being anxious, uneasy, feeling dizzy, confused, and drowsy, or feeling like you're about to pass out.
  • Ears ringing, hearing loss, speech problems, or vision problems.
  • The taste of metallic metal within your mouth or a tingling sensation in your mouth.
  • Muscle that is twitching and tremors; seizures (convulsions).
  • Breath that is weak or shallow.
  • High heart rate and the gasping sensation of extreme heat.
  • Low heart rate or weak pulse.
  • Very little or no urine.

Seek medical assistance right once if you develop methemoglobinemia, a dangerous illness. The symptoms are headaches and rapid heartbeats. Other symptoms include breathing problems, feeling tired or lightheaded, or skin that appears dull, gray, or blue-colored.

Common adverse reactions include:

  • Weakness, persistent numbness, or tingling.
  • Being tired or restless.
  • Tremors.
  • Headache, blurred vision, headache.
  • Rapid or slow heartbeats.
  • Breathing issues.
  • Chills or shivering.
  • Back pain.
  • Nausea, vomiting.

This isn't an exhaustive list of all the side effects. Other side effects could occur. Consult your physician to seek medical advice on adverse effects. You can report adverse reactions to the FDA at 1-800-FDA-1088.

Similar or related drugs

lidocaine eye drops, cocaine nasal, cefotaxime, bupivacaine, cefoxitin, piperacillin, and marcaine


Discuss with your doctor if you have ever experienced an adverse reaction when taking any kind of numbing medication. Certain epidural numbing medicines may have lasting or permanent effects on some body functions like sexual functioning, bladder or bowel control, and even movement or sensations in your feet or legs. Discuss with your physician the risk you face of nerve damage caused by Marcaine HCl.

Before you take this drug

Inform your doctor whether you've ever experienced an allergy reaction to a particular type of numbing medication or if you've had:

  • Anemia (lack of red blood cells).
  • The kidneys or liver illness.
  • A bleeding or blood clotting disorder.
  • Syphilis Polio, syphilis, a spinal cord or brain tumor.
  • Numbness or tingling.
  • Chronic backache and headaches resulted from surgery.
  • Blood pressure, blood pressure, or hypertension.
  • An abnormal curvature of the spine.

It isn't known if Marcaine HCl could affect a newborn baby. If you're not taking Marcaine HCl during childbirth, inform your physician that you are pregnant. It might not be safe to breastfeed while taking this medication. Talk to your doctor about any potential risks.

How to take Marcaine HCL?

Marcaine HCl is injected with an injection needle directly into or close to the area that is to be numbed. This injection is administered in a hospital or dental location. An epidural is an injection that takes place in the back. Marcaine is administered by injection via needles that are inserted into the region of your lower or middle back, near your spine. Your blood pressure, breathing, oxygen levels, and other vital indicators will be closely monitored. When you undergo a dental procedure, Marcaine HCl is delivered directly to the mouth, near either the teeth or the tooth that your dentist is working on. Certain epidural medications that numb the body can cause long-lasting effects on specific bodily functions, including sexual functioning, bladder or bowel control, as well as movement or sensations in your legs and feet. Discuss with your physician the risk you face of nerve damage caused by Marcaine HCl.

What happens if I miss a dose?

Because Marcaine HCl is prescribed as necessary prior to surgery or other dental treatment, you're unlikely to be following an exact dosing schedule.

What happens if I overdose?

Because Marcaine HCl is administered in a medical setting, it is monitored closely to ensure you don't get too much Marcaine HCl. Your medical staff will be quick to deal with you in case you experience symptoms of an overdose.

What should be avoided?

The medicine may cause numbness across a large part of the body. Following an epidural, you will not be in a position to feel or move the lower part of your body. Make sure you avoid injuries as you remain numb. Following a dental procedure, refrain from eating, chewing gum, or drinking hot drinks until your mouth is no longer feeling numb.

Interaction with other drugs

Inform your physician about any other medicines you are taking, particularly:

  • An antidepressant medication or antipsychotic.
  • Anti-nausea medications like Prochlorperazine (Compazine) or Promethazine (Phenergan).
  • Blood pressure medicine—carteolol, carvedilol, labetalol, nadolol, propranolol, sotalol, timolol.
  • A blood thinner like warfarin (Coumadin, Jantoven).
  • Ergot medicine—dihydroergotamine, ergotamine, ergonovine, methylergonovine.
  • An MAO inhibitor—isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

This list isn't complete. Other medications can affect Marcaine HCl, which includes prescription and over-the-counter medicines, vitamins, and herbal supplements. There are many possible interactions between drugs that are included in this article.