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Name of the Generic: Bupivacaine [bue-PIV-a-kane].
The Brand Names are: Marcaine HCl, Marcaine Spinal, Sensorcaine, Sensorcaine-MPF, Sensorcaine MPF Spinal, and Xaracoll.
Forms for Dosage: Injectable solution (0.0625%-0.9 percent; 0.1%-NaCl 0.9%; 0.125%-0.9 percent; 0.2%-NaCl 0.9%; 0.25 percent; 0.25% preservative-free; 0.25%-NaCl 0.9 percent; 0.5%; 0.5 percent preservative-free; 0.75% preservative-free); provide all three dosage forms.
Drug Class: Local injectable anesthetics.

What is Buprenorphine?

Bupivacaine is an anesthetic (numbing medication) that acts as a local (in only one location) anesthetic. Bupivacaine is an epidural injection in the spinal column in order to create the sensation of numbness in the labor process, during surgery, or during certain medical procedures. Bupivacaine can also serve as an anesthetic in dental procedures. Bupivacaine can also be employed for other purposes that are not covered in this guideline.

Side effects of  Bupivacaine

Take immediate medical assistance. If you notice symptoms that indicate an allergic reaction, such as itching, hives, a red skin rash, itching, and breathing difficulties, You may also experience sneezing or breathing difficulties, severe dizziness, vomiting, or swelling of your lips, face, and tongue. Inform your healthcare providers immediately in the event that you experience one of the following serious negative side effects:

  • Being anxious, restless, and confused. You may feel dizzy, lost, drowsy, anxious, or as if you're about to pass out.
  • Ears ringing, hearing loss, speech problems, or vision problems.
  • A metallic taste inside your mouth; numbness or the sensation of your mouth tingling.
  • Muscle that is twitching and tremors; seizures (convulsions).
  • Breathing that is shallow or weak.
  • Rapid heart rate, gasps, and feeling hot.
  • Low heart rate and weak pulse.
  • Very little or no urine.

Seek medical assistance right once if you develop methemoglobinemia, a dangerous illness. The symptoms are headaches and rapid heartbeats. Other symptoms include breathing problems, fatigue, feeling lightheaded, or skin that appears light, gray, or blue-colored.

Common adverse reactions include:

  • Weakness, numbness that lasts for a long time, or tingling.
  • Experiencing drowsiness or restlessness.
  • Tremors.
  • Blurred vision, headache.
  • Rapid or slow heartbeats.
  • Breathing issues.
  • Chills or shivering.
  • Back pain.
  • Nausea, vomiting.

This isn't an exhaustive list of all the side effects. Other side effects could be present. Consult your physician to seek medical advice on adverse effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.


Inform your doctor if you have had any allergic reactions to a particular type of numbing medication. Certain epidural numbing medicines may have lasting or permanent effects on specific bodily functions, including sexual function, bladder and bowel control, and even movement or sensation in your feet or legs. Consult your doctor about the specific risk you are facing of nerve damage resulting from bupivacaine.

Before you this drug

Discuss with your physician whether you've ever experienced an allergy to any form of numbing medication or if you've experienced:

  • Anemia (lack of red blood cells).
  • Renal or liver illness.
  • A bleeding or blood clotting disorder.
  • Syphilis Polio, syphilis, a spinal cord tumor, or a brain tumor.
  • Tingling or numbness.
  • Chronic backache and headaches due to surgery.
  • Blood pressure, blood pressure, or excessive blood pressure.
  • A spinal curvature that is abnormal in the spine.
  • Arthritis.

It isn't known if bupropion is harmful to a baby that is not yet born. If you're not receiving bupivacaine during your childbirth, inform your physician if you're expecting. Consult your physician regarding any risks.

How to take bupivacaine?

Bupivacaine is injected via the needle directly into or close to the area that is to be treated. It is administered in a hospital or dental location. In the case of an epidural, bupivacaine can be administered via a needle that is inserted within your lower back or middle, near your spine.Your blood pressure, oxygen levels, breathing, and other vital indicators are closely monitored.

In a dental procedure, the injection of bupivacaine takes place directly into your mouth, close to either the teeth or the tooth that your dentist is working on.Certain epidural drugs that cause numbness may cause long-lasting or permanent effects on specific bodily functions, including sexual function, bladder and bowel control, as well as movement or sensations in your feet or legs. Consult your doctor regarding the risk you face of nerve damage caused by bupivacaine.

What happens if I miss a dose?

Because bupivacaine is necessary prior to surgery or a procedure for teeth, you're unlikely to be on an exact schedule for dosing.

What happens if I overdose?

Since bupivacaine can be administered in an environment that is medical You will be monitored carefully to ensure that you do not take excessive amounts of the drug. The medical professionals will swiftly deal with you in case you experience symptoms of an overdose.

What should be avoided?

The medicine may cause numbness in a significant part of the body. Following an epidural, you will not be capable of feeling or moving the lower part of your body. Be careful not to cause injury when you're still in a state of numbness.

Following a dental procedure, refrain from eating, chewing gum, or drinking hot drinks until your mouth isn't as numb.

Interaction with other drugs

Discuss with your physician all other medications you take, including:

  • An antidepressant medication or antipsychotic.
  • Anti-nausea medication like prochlorperazine (compazine) or promethazine (phenergan).
  • Blood pressure medicine—carteolol, carvedilol, labetalol, nadolol, propranolol, sotalol, timolol.
  • A blood thinner like warfarin (Coumadin, Jantoven).
  • Ergot medicine—dihydroergotamine, ergotamine, ergonovine, methylergonovine.
  • Isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and other MAO inhibitors.

This list is not comprehensive. Other medications can affect the effects of bupivacaine. These include prescription and over-the-counter medicines, vitamins, and herbal remedies. There are many possible interactions between drugs. are outlined here.