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Generic Name: ibrexafungerp
Brand name: Brexafemme
Oral tablet (150 mg)
Drug class: antifungals

What is Ibrexafungerp?

Ibrexafungerp can be used to reduce the frequency of vaginal yeast infections in women and girls who are starting their periods.

Ibrexafungerp can be used in other ways not mentioned in this guide.

Side effects of Ibrexafungerp

If you experience any of the following symptoms of an allergic reaction, seek immediate medical attention: difficulty breathing, hives, swelling of the face, lips, or throat.

Ibrexafungerp can cause the following side effects:

  • Headache;
  • Loose stools, nausea, stomach pain, vomiting,

There may be other side effects. For medical advice about side effects, call your physician directly. Alternatively, the FDA can be reached at 1-800-FDA-1088 in order to report them.


Do not use it if you are pregnant. Use effective birth control.

Before you take this drug

If you have an allergy to ibrexafungerp, then it is best not to use it.Unborn babies may be harmed.If you are pregnant, do not take this medication. Inform your doctor immediately if you fall pregnant.

Before starting the treatment, you may be required to take a pregnancy test and have it come back negative. You may be asked to participate in a pregnancy study that tracks the effects of the drug on your baby if you are pregnant.Ask your doctor if you can safely breastfeed while taking ibrexafungerp.

Similar/related drugs

Fluconazole, topical nystatin, clotrimazole topical, diflucan, itraconazole, and miconazole topical

How to take Ibrexafungerp?

Read all instructions or guides that come with your medication and follow all instructions on the label. Follow the directions on the label.Ibrexafungerp can be taken with or without food.Ibrexafungerp should be taken twice daily.Use this medication at regular intervals of about 12 hours.Store away from heat and moisture at room temperature.

Details on dosage

Adult dose for vaginal candidiasis:

Take 300 mg twice daily for one day.
Doses should be given about 12 hours apart.
The total dosage of the treatment is 600 mg.
Use: To treat adult females with vulvovaginal Candida

The usual pediatric dose for vaginal candidiasis is:

Female postmenstrual: Orally take 300 mg twice daily for one day.
Doses should be given about 12 hours apart.
The total dosage of the treatment is 600 mg.
Use: To treat post menstrual females with vulvovaginal Candida.

What happens if I miss the dose?

If you are almost due for your next dose, skip the missed one. Never take two doses of the same medicine at once.

What happens if I overdose?

Call 1-800-222-1222 for poison help or seek immediate medical attention.

What should be avoided?

If your doctor prescribes any restrictions regarding food, beverage, or activity, follow their instructions.

Interaction with other drug

It is sometimes not safe to take certain medications at the same time. Some drugs may affect the blood levels of drugs that you are taking, causing side effects or making them less effective.

Ibrexafungerp may be affected by other drugs, such as prescription and over-the-counter medicines, vitamins, and herbal products. Inform your doctor of all the other medications you take.



Prescription only

Pregnancy & Lactation

CSA Schedule*
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