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Generic name: acetohydroxamic acid [a-SEET-oh-HYE-drox-AM-ik-AS-id]
Drug class: Miscellaneous genitourinary tract agents

What is Lithostat?

Lithostat prevents a buildup of ammonia that can cause a urinary tract infection. Ammonia buildup in urine can lead to the formation of renal stones.Lithostat helps to maintain low urine ammonia in patients with a particular type of chronic bladder infection.Lithostat does not contain an antibiotic. It will not treat infections. Lithostat may be used as part of a larger treatment plan that includes antibiotics for treating the infection and surgical removal of kidney stones. You should follow your doctor's advice.This medication guide does not list all possible uses for Lithostat.

Side effects of Lithostat

If you experience any of the following symptoms of an allergic reaction, seek emergency medical attention: hives, difficulty breathing, swelling of your lips, face, tongue, or throat.

Lithostat can cause serious side effects. If you experience:

  • If you feel your heart pounding or fluttering, then this is a sign that you are experiencing a cardiac arrest.
  • Signs of a blood clot in the leg: pain, swelling, warmth, or redness on one or both legs
  • Signs of a red cell disorder include a pale or yellowed complexion, dark urine, a high fever, or confusion.

Side effects of Lithostat include:

  • Headache on the first two days of treatment
  • Skin rash (especially if drinking alcohol is taken with Lithostat);
  • Nausea; upset stomach;
  • Depressed mood
  • Anxiety, tremors, or nervousness
  • Hair loss.

There may be other side effects. For medical advice on side effects, call your doctor. To report adverse effects, you can contact the FDA at 1-800-FDA-1088.

Similar/related drugs

Amoxicillin, Doxycycline, Ciprofloxacin, Cephalexin, Augmentin, Amoxicillin/clavulanate, and Ceftriaxone


Lithostat should not be used if your kidneys are ill or if bladder symptoms have not been examined by a physician.Lithostat may cause birth defects or harm to an unborn child. Do not use Lithostat if you are pregnant or are not using birth control.

Before you take this drug

Lithostat should not be used if:

  • Kidney disease
  • If you have bladder symptoms and your doctor has not run lab tests, then it is time to consult a physician.
  • If you are pregnant or if you do not use birth control,

Tell your doctor about any of the following to ensure that Lithostat will be safe for you:

  • Liver disease
  • Hemolytic Anaemia
  • A weak immune system.

FDA pregnancy category X This medicine may harm an unborn child or cause birth defects. Do not use Lithostat while pregnant. Use birth control to avoid pregnancy. Inform your doctor immediately if you fall pregnant or stop using birth control for any reason while taking this medicine.Acetohydroxamic acid does not pass into breast milk. It is unknown if this acid could harm a baby who is nursing. This medicine should not be taken while breastfeeding.

How to take Lithostat?

Please follow all the instructions on the prescription label. Your doctor may change the dose from time to time in order to get you the best results. Take Lithostat only as prescribed. Take the dose recommended and do not take more.Take Lithostat with an empty stomach at least one hour before or two hours after eating.Take this medicine every 6–8 hours. Please follow your doctor's directions.This medicine should not be shared with anyone else, even if the other person has similar symptoms. Lithostat should only be used by people who have a specific type of bladder infection.You may need to have frequent blood and urine tests while using Lithostat.Even if you don't have symptoms of a urinary infection, take this medication as prescribed. Lithostat does not act as an antibiotic, and it will not cure a bacterial infection. Follow the instructions on your antibiotic.Lithostat may be required for several years.Store away from heat and moisture at room temperature. When not in use, keep the bottle tightly shut.

What happens if I miss the dose?

As soon as you recall, take the missed dose. If your next scheduled dosage is approaching, skip the missed dose. You should not take more medicine to compensate for a missed dose.Take Lithostat only on an empty stomach.

What happens if I overdose?

Call 1-800-222-1222 for poison help or seek immediate medical attention.Overdose symptoms include nausea and a general feeling of ill health.

What should be avoided?

If you are taking Lithostat and drinking alcohol, it may cause a skin reaction (such as a rash, flushing, warmth, redness, or tingling).Consult your doctor before taking iron-containing vitamins or minerals.

Interaction with other drug

There are other drugs that may interact with acetohydroxamic acid, such as vitamins and herbal products. Inform your healthcare providers of all the medicines you are taking and those you plan to take.




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