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Generic names: dextromethorphan, guaifenesin, and pseudoephedrine [dex-troe-meth-OR-fan, gwye-FENce-sin, soo-doe-e-FED-rin].

Brand Names: Capmist DM, Despec Drops, Maxifed DMX, Poly-Vent DM, Trispec PSE… Display all 11 brands
Classification of drugs: upper respiratory combinations

What is Entre-Cough?

Dextromethorphan is an effective cough suppressant. It alters the brain signals that trigger the cough reflex.Guaifenesin is an expectorant. It assists in easing congestion from the throat and chest, which makes it easier to let your cough out by mouth.Pseudoephedrine can be described as a decongestant that shrinks blood vessels that line the nasal passages. Blood vessels that are dilated can cause the nasal passages to become congested (stuffy nasal congestion).Entre-Cough is a mixture of medicines to treat congestion, cough, sinus congestion, and chest congestion that is caused by allergies, or it can also treat the commonly occurring cold as well as influenza.Entre-Cough cannot treat a cough due to smoke, asthma, or emphysema.Entre-Cough can also be employed for other purposes that are not covered in this guideline.

Side effects of Entre-Cough

See a doctor immediately. If you are experiencing symptoms or warning signs of an allergic response, like hives, trouble breathing, or swelling of your lips, face, and tongue,This medication could cause severe adverse effects. Take this medication off and contact your doctor immediately if you experience:

  • Rapid or irregular heart rate;
  • Extreme disorientation as well as anxiety that makes you feel like you're going to faint;
  • Severely migraine;
  • Mood swings;
  • Fever
  • Extremely dangerously high blood pressure (severe headache, blurred vision, a hearing buzzing chest pain, anxiety, unsteady heartbeats, seizures).

Common adverse effects of Entre-Cough could include:

  • Diarrhea;
  • Dizziness, drowsiness;
  • Sleep problems (insomnia);
  • Being anxious, restless, or angry.

This isn't an exhaustive list of all the side effects. Other side effects could occur. Consult your physician to seek medical advice on the effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.


Do not take Entre-Cough if you've used an MAO inhibitor within the last 14 days, including isocarboxazid or linezolid, blue injections, phenelzine rasagiline, selegiline, or tranylcypromine.

Prior to using this drug

This medication is recommended if you have an allergy to dextromethorphan, guaifenesin, or pseudoephedrine.Do not take this medication. If you've previously used an MAO inhibitor within the last 14 days, Serious interactions between drugs can occur. MAO inhibitors include isocarboxazid rasagiline, phenelzine and linezolid selegiline, tranylcypromine, and isocarboxazid.

Consult a physician or pharmacist if it's safe to take Entre-Cough if:

  • Hypertension and coronary artery diseases;
  • Diabetes;
  • Glaucoma;
  • Epilepsy or another seizure disorder
  • An overly large prostate or urinary problems
  • Pheochromocytoma (an adrenal gland's tumor)
  • Cough that is mucusy or cough due to emphysema as well as chronic bronchitis.

It isn't known if Entre-Cough can cause harm to an unborn baby.Before taking this medication if you are pregnant, always seek advice from your physician first.The medicine could pass through breast milk and harm a nursing child. Decongestants could also reduce the production of breast milk. Consult a physician before taking this medication if you are breastfeeding babies.Artificially sweetened cold medication may contain phenylalanine. If you suffer from phenylketonuria (PKU), be sure to check the label on your medication to determine whether the product contains the chemical phenylalanine.

How do I take Entre-Cough?

Take exactly as indicated on the label or as directed by your physician. Avoid using larger than smaller amounts or for longer than suggested. Medicine for colds and coughs is usually only used for a brief period of time until the symptoms subside.Don't give this medication to children younger than four years old. Always consult a physician prior to giving a cold or cough medicine to children. Death can occur because of the misuse of cold and cough medicines by very young children.Do not chew, crush, or break extended-release tablets.Take it in whole.Measure the amount of liquid medicine using the dosing needle provided, a dosing spoon, or even a medicine cup. If you don't have an instrument for measuring doses, you can ask your pharmacist for one.Drink plenty of fluids to ease congestion and smooth your throat when you are taking this medication.

If you require surgical intervention or tests for medical reasons, inform the doctor or surgeon before the appointment time if you have taken Entre-Cough in the past couple of days.Do not take more than seven days in a row. Discuss with your doctor when your symptoms do not improve after seven days of treatment or if you suffer from a headache, fever, or skin eruption.Storage at room temperature is free of heat and moisture. Don't allow the liquid medicine to become frozen.

What happens if I miss the dose?

Since this medication is used only when it is needed, you might not be in a routine for taking your dose. If you take the medication frequently, you should take the missed dose whenever you remember. Do not take your missed dose if it's close to the time of your next dose. Don't take additional medicine to make up for the missed dose.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact for help at the Poison Helpline at 1-800-222-1222.

Avoid this

The condition can cause blurred vision or even impair your reactions or thinking. Be aware if you drive or engage in any activity that requires that you be aware and capable of seeing clearly.Alcohol consumption can cause an increase in the effects of this medication.Consult a physician or pharmacist before taking any other cough, cold, or allergy medication. Entre-Cough can be found in a variety of combinations of medicines. When you combine certain products, it can result in excessive amounts of a specific medicine. Look at the label to determine whether a medication contains an expectorant, a decongestant, or a cough suppressant.

Interaction with other drug

Consult a physician or pharmacist prior to using this medication if you're taking any other medications that include prescription or over-the-counter medications, vitamins, and herbal products. Certain medications can trigger unwanted or harmful effects when taken together. Some interactions may not be mentioned in this medication guide.If you take this medicine in conjunction with other medications that make you sleepy or slow your breathing, this could make these effects worse. Consult your physician before using this medication with sleeping pills, narcotic pain medicine, muscle relaxers, or any other medication that treats depression, anxiety, depression, or seizures.