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Jadenu Sprinkle

Generic name: deferasirox [de-FER-a-sir-ox]
Brand names: Exjade, Jadenu, and Jadenu Sprinkle

What is Jadenu Sprinkle?

Sprinkled Jadenu binds iron and removes it from the bloodstream. Jadenu Sprinkle treats iron overload due to blood transfusions in both adults and children older than 2 years. Jadenu Sprinkle can also be used to treat chronic blood disorders caused by genetic blood disorders in children and adults older than 10 years. Jadenu Sprinkle can be used in other ways not mentioned in this guide.

Side effects of Jadenu Sprinkle

If you experience symptoms of an allergic reaction, such as hives, difficulty breathing, swelling on your face or in your throat, or a severe reaction to your skin (fever or sore throat, pain in the eyes, or skin irritation), or if your skin has rashes that are red or purple and cause blistering or peeling, seek emergency medical attention.

Jadenu Sprinkle may cause serious side effects. If you experience:

  • Problems with hearing or vision
  • Kidney problems: little or no urine, swelling of the feet or ankles, and feeling tired or breathless;
  • Liver problems: nausea; itching; fatigue; dark urine; and clay-coloured stools. Jaundice.
  • Low blood cell counts can cause fever, chills, and mouth sores. They may also be accompanied by pale skin, easy bruises, unusual bleeding, or cold hands or feet.
  • Signs of stomach bleeding include bloody or tarry stool, vomiting blood, or vomit that looks like coffee grounds.

In older adults, serious side effects are more likely to occur.

Some of the common side effects that Jadenu sprinkle may cause include:

  • Nausea, vomiting, and stomach pain;
  • Diarrhoea; or
  • Skin rash.

There may be other side effects. For medical advice on side effects, call your doctor. The FDA can be contacted at 1-800-FDA-1088 to report side effects.


If you are suffering from severe kidney disease, liver disease, advanced cancer, a disorder of the blood cells or bone marrow, or if your blood platelet levels are low, then Jadenu Sprinkle is not for you.

Jadenu sprinkles can cause liver or kidney damage. Contact your doctor immediately if you experience swelling, shortness of breath, pain or discomfort in the upper stomach, lack of urination, dark urine or clay-coloured stool, or jaundice.

Jadenu Sprinkle can also cause stomach and intestinal bleeding. If you experience symptoms of stomach bleeding, such as bloody or black stools or vomiting blood or coffee grounds, call your doctor immediately.

Before you take this drug

This medication should not be used it:

  • Severe liver or kidney disease
  • Advanced cancer
  • A bone marrow disease;
  • Low levels of platelets are a sign that your blood is low in platelets.

Tell your doctor about any of the following:

  • Kidney disease
  • Liver disease
  • Anaemia
  • Cancer (especially blood-cell cancers such as leukaemia);
  • A stomach ulcer
  • Stomach or intestinal bleeding
  • Vision or hearing problems
  • A weak immune system can be caused by a disease (such as cancer, HIV, or AIDS) or by taking steroids, chemotherapy, or radiation.

This medicine is not known to harm an unborn child. Inform your doctor if you are pregnant or planning to become pregnant. Jadenu Sprinkle may make birth-control pills ineffective. Ask your doctor if you can use non-hormonal birth controls to prevent pregnancy (condoms, diaphragms with spermicide). Jadenu Sprinkle should not be taken while breastfeeding.

How to take Jadenu Sprinkle?

You may be tested by your doctor to ensure that you are not suffering from any conditions that would make it unsafe for you to use Jadenu Sprinkle. Read all instructions or guides that come with your medication and follow all directions. Follow the directions on the label. Every day, take Jadenu Sprinkle. Take Exjade at least 30 minutes prior to eating. Jadenu can be taken on an empty stomach or with a low-fat snack. If you cannot swallow the jadenu whole, mix it with water in a glass. If you are unable to swallow the Jadenu tablets whole, you can crush them and mix them with yoghurt, applesauce, or any other soft food. Open the package and sprinkle the medicine on a small amount of soft food.

Do not chew the mixture after mixing crushed tablets or sprinkles into soft food. Don't save it to use later. Don't chew, crush, or swallow the Exjade dispersible tablets. Place the tablet in a glass filled with apple juice, water, or orange juice, and let it dissolve. The tablet won't dissolve completely. This mixture should be consumed immediately. Pour to ensure you receive the full dose; add some more liquid in the same glass. Swirl gently, then drink immediately.

If you are taking less than 1,000 milligrammes (1g) per day, dissolve the Exjade tablet in half a cup of orange juice, apple juice, or water. If you are taking more than 1000 mg daily, dissolve the tablet into about 1 cup of apple juice, water, or orange juice. You may require frequent blood tests. You may also require a liver biopsy and a checkup every six months on your kidney or liver functions. Store away from heat and moisture at room temperature.

What happens if I miss the dose?

If you are almost due for your next dose, skip the missed one. Never take two doses of the same medicine at once.

What happens if I overdose?

Call 1-800-222-1222 for poison help or seek immediate medical attention.

Avoid this

Use only the iron-chelating medicine deferoxamine or desferal if your doctor has prescribed it. Avoid taking antacids containing aluminium, such as Amphojel, Gaviscon Maalox, Mi-Acid, Mylanta Rulox, and other brands. Jadenu Sprinkle can impair your reactions or thinking. You should be careful when driving or doing anything else that requires you to remain alert.

Interaction with other drug

It is sometimes not safe to take certain medications together. Some drugs may affect the blood levels of drugs that you are taking, increasing side effects or making them less effective.

Jadenu Sprinkle can be affected by many drugs. These include prescription and over-the-counter medicines, vitamins, and herbal products. This list does not include all possible interactions. Inform your doctor of all medications you are currently taking and those that you will stop or start using.