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Adrucil (injection)

Generic Name: Fluorouracil (injection) [FLOOR-oh-URE-a-sil]
The Brand Name is Adrucil injection.
Drug Class: Antimetabolites

It is believed that the Adrucil brand name has been removed from the U.S. If the generic version of this product were approved by the FDA, it is possible that there would be similar generic versions available.

What is Adrucil?

Adrucil is a treatment for cancer in the rectum, colon, stomach, breast, or pancreas.Adrucil is typically used in combination with chemotherapy and other cancer medications.Adrucil is also employed for other purposes that are not covered in this guideline.

Side Effects Of Adrucil

Contact a medical professional immediately. If you are experiencing symptoms that indicate an allergic reaction, such as difficulty breathing, hives, or swelling of your lips, face, or tongue,

Adrucil may cause serious side effects. Contact your doctor immediately. If you suffer from:

  • Fever (take your temperature every day while you take Adrucil);

  • Chronic or persistent diarrhea; persistent or severe diarrhea;

  • Issues with vision;

  • Difficulty in balance, confusion, or muscle movement

  • Sores in the mouth that hurt, swelling or red gums, trouble swallowing, eating, or talking;

  • Bone marrow suppression—dizziness, pale lips or fingernail beds,

    fast heart rate

    , getting easily tired or short of breath;

  • hand and foot syndrome: pain, blisters, bleeding, or severe "Hand and foot syndrome"—rash, blisters, or pain on the hand's palms or on the feet's soles

  • Heart issues: chest pressure or pain, expanding into your shoulder or jaw, irregular heartbeats, sickness, sweating, getting dizzy or breathless

The treatment for cancer may be delayed or discontinued permanently when you experience certain negative side effects.

Common adverse effects of Adrucil could include:

  • Diarrhea;

  • Mouth sores;

  • Heart conditions

  • Suppressing the marrow.

This is not a comprehensive list of all the side effects. Others could happen. Consult your physician to seek medical advice on the effects. You can report symptoms to the FDA at 1-800-FDA-1088.


Before you use Adrucil, consult your physician about any medical issues or allergies, any medications you take, and if you're nursing or pregnant.

Before You Take This Drug

Speak to your doctor if you have ever suffered from:

  • A metabolic disorder called DPD (dihydropyrimidine dehydrogenase) deficiency;

  • Heart issues heart problems

  • Bone, the marrow Depression of the bone marrow.

Men and women who use Adrucil must use effective birth control to stop the pregnancy. Adrucil can harm the unborn child if the father or mother uses this medication.

Continue using contraceptives until at least three months have passed following the last dose. Inform your doctor immediately when you notice a pregnancy when one of the mothers or fathers is taking Adrucil.The medicine can affect fertility (the ability to bear children) in both males and females. It is nevertheless important to utilize birth control to stop pregnancy, as Adrucil could affect the unborn baby.It is not recommended to breastfeed while taking this medication.

How to Take Adrucil?

Adrucil is administered as an infusion into the vein. The healthcare professional will give you the injection.The first dose is given in an in-hospital or clinic setting to treat any severe negative side effects.

Adrucil is typically given in the course of a treatment, and it is possible to take the drug only on certain days during every cycle. The medicine can be administered by continuous infusions over the course of 24 to 46 hours.

How often you require Adrucils is contingent on a variety of aspects, including the effects of adverse effects and how your body reacts to the medication. Your doctor will decide on the duration of treatment with this drug.

Inform your doctor if you experience any burning, pain, or swelling in the area of your IV needle after Adrucil is administered.

Adrucil may increase the chance of suffering from bleeding or

an infection

. It is recommended to have regular medical tests. The treatment you receive for cancer could be delayed based on the outcomes of the tests.

What Happens If I Miss a Dose?

Contact your doctor for advice. If you do not make an appointment to receive your Adrucil,

What Happens If I Overdose?

Since the medication is prescribed by a medical specialist in a medical setting, the risk of overdose is less likely to occur.

What Should be Avoided?

Avoid being around those with illnesses or who suffer from infections. Contact your doctor right away in the event that you show symptoms of an infection.

Interaction With Other Drugs

If you are taking an anticoagulant (warfarin, Coumadin, or Jantoven), it is possible that you will need to take regular "INR" or prothrombin time tests.Other medications can affect Adrucil, which includes prescription and over-the-counter medicines, vitamins, and herbal products. Inform your physician about your current medications as well as any medicines you are about to start or stop taking.



Prescription only

Pregnancy & Lactation

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