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Sudafed PE Pressure Plus Pain

Generic name: Acetaminophen and phenylephrine [a-SEET-a-MIN-oh-fen-and-FEN-il-EFF-rin]
Brand names: Acetaminophen Congestion and Pain, Alka-Seltzer Plus Cold and Sinus, Excedrin Sinus Headache, Mygrex, Sudafed PE Pressure Plus Pain, etc. display the 20 different brands.
Classification of drugs: upper respiratory combinations

What is Sudafed PE Pressure Plus Pain?

Acetaminophen is an anti-inflammatory and a fever-reducer. Phenylephrine is an anti-congestant that reduces blood vessels in the nasal passages. Blood vessels that are dilapidated can lead to nasal congestion (a stuffy nose). Sudafed PE Pressure Plus Pain is a mix of medicine that treats headaches and body aches, fever, congestion of the nose, and sinus congestion that is caused by allergies, the common cold, or the flu.

Side effects of Sudafed PE Pressure Plus

See a doctor immediately. If you notice one of the following symptoms of an allergic reaction: hives; trouble breathing; and swelling of your lips, face, and tongue.

In rare instances, acetaminophen can cause an extreme skin reaction that can result in death. This could occur even if you've taken acetaminophen before and did not experience any reaction. Stop taking Sudafed PE Pressure Plus Pain and contact your doctor immediately in the event of the appearance of a rash or skin redness that can cause peeling and blisters. If you have this kind of reaction, you should not take any medication that contains acetaminophen.

The medicine can cause serious adverse effects. Stop taking the medication and consult your doctor right away in the event of:

  • Either a slow, fast, or irregular heart rate;
  • Confusion, hallucinations;
  • Tremor, seizure (convulsions);
  • Very little or no urination;
  • Nausea, stomach pain, itching, and loss of appetite dark urine, stools with a clay-colored color, jaundice (yellowing of the eyes or skin), or
  • Extremely dangerously high blood pressure (severe headache, blurred vision, buzzing in your ear, anxiety, confusion, chest pain, shortness of breath, seizures).

Common adverse negative effects Sudafed PE pressure and pain could include:

  • Dizziness, weakness;
  • Mild headache;
  • Mild nausea, diarrhea, or upset stomach
  • Runny nose;
  • Being anxious or anxious, restless, or anxious
  • Sleep problems (insomnia).

This is not an exhaustive list of side effects. Other side effects could occur. Contact your doctor for advice on medical adverse effects. You can report any side effects to the FDA at 1-800-FDA-1088.

Similar or related drugs

Epinephrine topical, pseudoephedrine, phenylephrine nasal, mometasone nasal, sodium chloride nasal, Afrin, and Nasonex 24HR Allergy


Do not take this medicine if you have previously taken an MAO inhibitor within the past 14 days. A drug interaction that is dangerous could occur. MAO inhibitors are isocarboxazid rasagiline, phenelzine, linezolid selegiline, tranylcypromine, and selegiline. Don't take any more than what is recommended. A high dose of acetaminophen could damage your liver and lead to your death. Call your doctor immediately if you experience nausea, discomfort in your stomach area, itching, a lack of appetite, dark urine, stools with a clay-colored color, or jaundice (yellowing of your eyes or skin). an itch or redness on your skin that gets worse and causes blisters and peeling.

Before you take this drug

It is not recommended to use Sudafed PE Pressure Plus for pain if you are allergic to acetaminophen (Tylenol) or phenylephrine. Do not take this medicine if you have previously taken an MAO inhibitor within the last 14 days. A potentially dangerous drug interaction could occur. MAO inhibitors are isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine. Ask your doctor or pharmacist whether it is safe to take this medication in the event of any other medical condition, particularly:

  • Liver disease, cirrhosis, or an underlying past history of alcoholism, or if you consume more than three alcoholic drinks every day;
  • High blood pressure, heart disease, coronary artery disease;
  • Thyroid that is overactive;
  • Pheochromocytoma (an adrenal gland tumor) or
  • If you are taking an antidepressant.

It is not clear if Sudafed PE Pressure Plus Pain could harm a baby who is not yet born. Do not take cold or cough medicine without consulting your doctor when you are pregnant.

Acetaminophen and phenylephrine can be absorbed into breast milk and cause harm to the baby who is nursing. Decongestants can also affect the production of breast milk. Do not take cold or cough medicine without consulting your doctor if you're pregnant.

Always consult a doctor before giving a cold or cough medicine to children. Death can occur due to the ineffective use of cough and cold medications when children are very young.

How to take it?

Follow the directions on the label or as directed by your physician. Do not take longer than suggested. Cold medicine is typically taken for a brief period of time until symptoms improve. Take no more than what is recommended. An acetaminophen overdose could damage your liver or cause death. Mix the mixture thoroughly and drink it all immediately.

Drop the tablets in the glass of water (at least 4 ounces or 12 cups). Mix it up and drink it all immediately. Stop taking the medication and call your doctor if you suffer from a fever even after 3 days of treatment, if you are still experiencing symptoms after 7 days (or 5 days if you are treating children), if your symptoms worsen, if you experience an underlying skin rash or headache that continues to recur, or if you experience any swelling or redness. If you require surgery or medical tests, inform your doctor or surgeon prior to the time of your appointment if you have taken this medication within the last few days.

Keep the storage at room temperature, away from heat and moisture.

What happens If I miss a dose?

Because Sudafed PE Pressure Plus Pain must be taken only at times of need, you may not be on a regular dosing schedule. If you take this medication on a regular basis, make sure to take the dose you missed immediately when you remember. Don't miss your missed dose if you are nearing the time when your next dose is due. Don't take any additional medicine to make up for the missed dose.

What happens if I overdose?

Seek medical attention in an emergency situation or contact the Poison Helpline at 1-800-222-1222. Acetaminophen in excess could be fatal.

The first symptoms of an acetaminophen overdose include a loss of appetite, nausea, vomiting, stomach pain, sweating, and weakness or confusion. Later symptoms could include discomfort in your stomach, dark urine, and the appearance of yellowing on your skin or the whites of your eyes.

What should be avoided?

This medication can affect your ability to think or react. Be aware when you drive or do things that require you to remain vigilant.

Consult a physician or pharmacist prior to using any cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is found in a wide variety of combination medications. Combining certain medicines can result in too much acetaminophen and an unfatal overdose. Check the label to find out if the medicine includes acetaminophen or APAP.

Do not drink alcohol. It can increase the chances of suffering liver damage when taking acetaminophen.

Interaction with other drugs

Other drugs can interact with phenylephrine and acetaminophen, including prescription and over-the-counter medications, vitamins, and herbal products. Inform all of your health care providers about the medications you are currently taking and any medications you begin or stop taking.