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Bacitracin and polymyxin B topical

Generic name: bacitracin and polymyxin B topical [BAS-i-TRAY-sin-and-POL-ee-MIX-in-B]
Brand names: Double Antibiotic, Polysporin, Simply Neosporin, Polysporin Ointment, Polytracin, Betadine Antibiotic
Topical ointment: dosage form (500 units–10,000 units/g)
Class of drugs: topical antibacterials

What is Bacitracin and polymyxin B topical?

Bacitracin and Polymyxin B Topical (for skin) are a combination of medicines used to prevent infection from cuts, scrapes, and/or burning.This medication guide does not list all possible uses for bacitracin or polymyxin B.

side effects of Bacitracin and polymyxin B topical

If you experience any of the following symptoms of an allergic reaction, seek immediate medical attention difficulty breathing, hives, swelling of your lips, face, tongue, or throat.If you are experiencing any of the following symptoms, stop using bacitracin or polymyxin topically immediately and contact your doctor.

  • You need to take this medication for more than one week.
  • Your condition continues or worsens.
  • A rash or another allergic reaction occurs.

You may experience less serious side effects or none at all.There may be other side effects. For medical advice on side effects, call your doctor. The FDA can be contacted at 1-800-FDA-1088 to report side effects.


Use exactly as directed on the package and label. Adhere to the instructions found on both packages and labels.

Before you take this drug

If you have an allergy to bacitracin or polymyxin B, then it is best not to use the topical.Avoid using bacitracin or polymyxin topical on large areas of the body and in your eyes.

If you suffer from:

  • Deep or puncture wounds
  • Animal bites
  • Serious burns

Consult your doctor before taking this medication if you're pregnant or nursing.Do not administer this medicine to an infant without consulting a doctor.

How to take Bacitracin and polymyxin B topical?

Comply with any instructions on the label or as set out by your physician.Before and after using bacitracin or polymyxin topical, wash your hands.Apply the topical Bacitracin/Polymyxin B to the affected area between 1 and 3 times per day. Before using this medication, clean the affected area. You can cover the area where you apply this medicine with a sterile dressing.Use bacitracin and polymyxin topically for no more than one week, unless directed by your doctor.Store away from heat and moisture at room temperature.

What happens if I miss the dose?

If your dose is close, do not take an additional dosage. If this has occurred, skip that missed one altogether and continue as planned with your schedule. Never apply two doses at once.

What happens if I overdose?

If anyone accidentally swallows the medicine, seek emergency medical care or call Poison Help at 1-800-222-1222.

What should be avoided?

Do not use other medications to treat the same area that you have treated with bacitracin or polymyxin B topical, unless you are told by your doctor.

Interaction with other drug

Inform your doctor of all medicines you take, including both prescription and over-the-counter treatments.Inform your doctor of all the medications you are taking, including over-the-counter and prescription medicines, vitamins, and herbal remedies.