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Generic name: Mepivacaine
Drug class: local injectable anesthetics

What is Mepivacaine?

Mepivacaine blocks nerve signals that transmit pain to the brain. Mepivacaine can be used to anesthetize an epidural block or spinal block. Also, it is used for anesthetic dental procedures. Mepivacaine can be used in other ways not mentioned in the medication guide.

Side effects of Mepivacaine

If you experience any of the following symptoms, seek emergency medical attention: nausea, vomiting, feeling hot or sweaty, rapid heartbeats, sneezing, difficulty breathing, dizziness, and fainting.

If you:

  • Metallic taste or tingling sensation in the mouth; numbness in the lips and mouth.
  • Headache, blurred vision, or ringing in the ears;
  • Feeling like you could pass out; confusion; severe drowsiness
  • Slow heartbeat, weak pulse, or weak breathing
  • Fever, stiff neck, and increased light sensitivity
  • Feeling anxious, restless, or having tremors or muscle twitching;
  • Continued numbness or weakness in the legs or feet.
  • Loss of bladder and bowel control
  • Loss of sensation in the lower abdomen, groin, or genitals
  • Urination that is painful or difficult
  • Rapid heartbeat. Feeling hot.

Side effects common to mepivacaine include:

  • Feeling anxious, restless, or excited
  • Depression, dizziness;
  • Tremors;
  • Ringing in the ears and blurred vision

There may be other side effects. For medical advice on side effects, call your doctor. Report side effects by calling the FDA at 1-800-FDA-1088.

Similar/related drugs

Lidocaine ophthalmic, cocaine nasal, and buprevacaine


The effects of spinal numbing drugs can be long-lasting and permanent on the body. Speak to your doctor regarding your particular risk of damage caused by mepivacaine.

Before you take this drug

If you've ever experienced an allergic reaction, do not use mepivacaine.

Tell your doctor about any of the following to ensure that mepivacaine will be safe for you:

  • Liver or kidney disease
  • Low or high blood pressure
  • Heart disease or stroke history;
  • Heart rhythm disorder
  • Coronary artery disease
  • Epilepsy
  • Drug allergy
  • If you use medicines regularly (especially for headaches or depression),

FDA pregnancy class A There is no information on whether or not mepivacaine can harm a developing baby. You should tell your doctor immediately if you plan to get pregnant or if you are pregnant. It is unknown whether mepivacaine can pass into breast milk or whether it can harm nursing babies. You should tell your doctor that you are breastfeeding a child.

How to take Mepivacaine?

Mepivacaine can be injected in an area near the spine of your lower back for an epidural block or spinal block. This injection will be given in an operating room or hospital. Mepivacaine can be injected inside the mouth to treat gum disease. This injection will be given in the dental office or during oral surgery. While you receive mepivacaine, your breathing, oxygen level, blood pressure, and other vital indicators may be closely monitored. The effects of spinal numbing drugs can be long-lasting and permanent on the body. Sexual function, bladder or bowel control, and the movement of your feet or legs are all affected. Speak to your doctor regarding your particular risk of nerve injury from mepivacaine.

What happens if I miss the dose?

You are unlikely to have a schedule for mepivacaine dosing since it is only given when needed, before surgery or any other medical procedures.

What happens if I overdose?

If you believe you've received too much mepivacaine, tell your caregiver right away. Overdose symptoms include extreme sleepiness, convulsions (convulsions), shallow breath, or a slow heartbeat.

What should be avoided?

Avoid eating or chewing gum after your dental treatment until you feel your teeth again. Mepivacaine may cause you to feel numb for an extended period of time. If you chew while your lips or tongue are numb, it could cause a bite to occur.

Interaction with other drug

Mepivacaine may also interact with other drugs, such as prescription or over-the-counter medications, vitamins, and herbal products. Inform your healthcare providers of all the medicines that you are currently taking and those that you plan to start using.