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Generic name: coagulation factor IX [koe-AG-yoo-LAY-shun-FAK-tor-NINE]
Brand names: alphanine SD (Alprolix), benefix (Idelvion), Ixinity (Ixinity),… Show all 8 brands.
Drug class: Other coagulation modifiers

What is Idelvion?

Idelvion can be used to treat or stop bleeding in people who have hemophilia A. This medication should not be used to treat people with hemophilia B factor 8 deficiency.

Idelvion can be used in other ways not mentioned in this guide.

Side effects of Idelvion

If you experience any of the following: hives, itching, wheezing, tightness in your chest, difficulty breathing, blue lips, feeling as if you may pass out, swelling on your face, lips, or tongue, swelling around your throat, and/or a rapid heartbeat,

Idelvion can cause serious side effects. If you experience:

  • Weight gain is swelling of the hands, lower legs, and waist.
  • Loss of appetite
  • Fever or chills
  • Continued bleeding after treatment
  • New or worsening bleeding
  • Signs of excessive blood clotting include sudden numbness, weakness, slurred or slurred speaking, difficulty with vision, balance, chest discomfort, blood in the cough, or swelling, pain, heat, and redness on one or both legs.

Idelvion can cause a variety of side effects.

  • Nausea;
  • Headache;
  • Dizziness;
  • Changed sense of taste
  • Mild skin rash;
  • Injection site pain, irritation, and redness.

There may be other side effects. For medical advice on side effects, call your doctor. The FDA can be contacted at 1-800-FDA-1088 to report side effects.

Similar/related drugs

Hemgenix, Alprolix, novoseven RT, Profilenine, Factor ix complex, and benefix


Please read all the instructions on the label or package of your medication. Inform your healthcare provider about your medical conditions, allergies, and medicines.

Before you take this drug

Idelvion should not be used if you:

  • You have an allergy to the clotting factor medication.
  • You have signs of excessive bleeding.
  • You are allergic to the hamster protein.

Tell your doctor about any of the following:

  • Kidney disease
  • Liver disease
  • Coronary arterial disease or hardening of the arteries
  • A stroke or heart attack

Tell your doctor whether you're pregnant or breastfeeding.Idelvion, which is made of donated plasma from humans, may contain viruses and other infectious agents. Plasma donated is treated and tested to reduce the chance of contamination. However, there is still some risk that it may transmit disease. You should ask your doctor if there are any risks.

How to take Idelvion?

Follow the directions in the guide or instructions that come with the medication. Your doctor may change your dose. Take the medicine exactly as directed.Your first dose may be administered in a hospital setting or clinic to treat any serious side effects.

Idelvion can be given by infusion through a vein. Your healthcare provider may give you your first dose and teach you how to use the medication properly.You should read all the instructions that are included with your medicine. Ask your pharmacist or doctor for assistance if you don't understand.Idelvion should be diluted with a liquid before use. If you are using injections on your own, make sure that you know how to mix and store them.

The mixture should be clear, yellow, or colorless. Prepare an injection only when you are ready to administer the drug. If the medicine is cloudy, has changed color, or contains particles, do not use it. For new medicine, call your pharmacist.Do not shake or stir the medicine. You may ruin it. Do not use the injection for 3 hours after mixing.Blood tests may be required frequently.

Wear or carry medical identification in case of an emergency to let others know that you have a bleeding disorder.Follow the instructions on the label of your medicine about how to store powder medicine and diluent. Coagulation Factor IX is available in different forms. Some can be stored at room temperature, while others need to be kept cold. Do not freeze. Do not expose the medication to sunlight.

Each vial is only for one-time use. After one use, throw it out, even if the medicine is still inside.After the expiration dates have passed, throw away any remaining Idelvion.

Only use a needle or syringe once, and then store them in a "sharps container" that is puncture-proof. Be sure to follow local or state laws on how to properly dispose of the container. Keep the container out of reach of pets and children.

What happens if I miss the dose?

If you miss a dosage, call your doctor to get instructions.

What happens if I overdose?

Call 1-800-222-1222 for poison help or seek immediate medical attention.

What should be avoided?

If your doctor prescribes any restrictions regarding food, beverage, or activity, follow their instructions.

Interaction with other drug

Idelvion may be affected by other drugs, such as prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all medications you take, including those you start or stop using.