What is the Isovue M-300?
Isovue M-300 is a radiopaque contrast agent (RAY DEE OOH PAYK). This medicine contains iodine, which is a substance capable of absorbing x-rays. The radiopaque contrast agent is used to make it easier to see blood vessels, organs, and non-bony tissue on a CT scan.
The Isovue M-300 can be used to diagnose certain disorders of the heart, brain, and blood vessels, as well as the nervous system. This medication guide does not list all possible uses of Isovue M-300.
Side effects of Isovue-M-300
If you experience symptoms of an allergic reaction, such as hives, difficulty breathing, swelling on your face or in your throat, or a severe reaction to your skin (fever or sore throat with burning, pain in the eyes, or skin rash, which is red or purple and blisters or peels), seek emergency medical attention.
If you experience a severe drug reaction, seek medical attention. This can include a skin rash, fever, or flu-like symptoms. Other symptoms may include muscle aches or weakness, bruising, or unusual swelling.
Isovue M-300 can cause serious side effects. If you experience:
- Anxiety or dizziness that makes one feel as though they could faint is a common symptom of anxiety disorders, but other times the feeling of lightheadedness may arise from other causes as well.
- Weight and fluid gain occur rapidly, yet little or no urinating occurs.
- Difficulty breathing
- Seizure (convulsions);
- You may experience swelling of the neck or throat.
- Symptoms of thyroid disease include extreme tiredness, dry skin, stiffness or joint pain, muscle weakness or pain, hoarseness in voice, sensitivity to cold temperatures, and weight gain.
- Heart attack symptoms: chest pain or pressure, spreading pain to your jaw and shoulders, nausea, or sweating.
- Signs of a blood clot in the lungs: chest pain, sudden cough, and shortness of breath; coughing blood.
- Signs of a stroke include sudden numbness and weakness, especially on one side; a severe headache or slurred or shaky speech; or problems with vision or equilibrium.
Side effects that may occur with Isovue M-300 include:
- Chest pain;
- Slow heartbeat
- Hot flashes; burning sensation
- Flushing (warmth, redness, or tingling feeling)
- Nausea;
- Hives
There may be other side effects. For medical advice on side effects, call your doctor. The FDA can be contacted at 1-800-FDA-1088 to report side effects.
Similar/related drugs
Diazepam, valium, simethicone, hyoscyamine, levsin, and iopamidol
Warnings
If you are infected with it, Isovue M-300 should not be given to you.
Before you take this drug
Inform your physician of any of the following issues:
- Any type of reaction to a contrast agent.
- Liver or kidney disease
- Heart failure, including congestive heart disease.
- Stroke, blood clots, or coronary arterial disease.
- Asthma; hay fever; food allergies
- Epilepsy
- Sickle-cell anemia
- Diabetes;
- An active infection
- Pheochromocytoma
- Multiple myeloma; bone cancer
- A thyroid disorder.
Isovue-M-300 is not known to harm an unborn child. Inform your doctor if you are pregnant. Inform your doctor if breastfeeding is taking place.
How can the Isovue M-300 be used?
Infusion of Isovue M-300 into an artery or vein is possible. This injection will be given by a healthcare provider. While you receive Isovue M-300, you may be prescribed medication to help prevent certain side effects. If you experience any pain or swelling when receiving Isovue M-300, tell your carers.
Drink more fluids both before and after the radiologic test. Dehydration can be caused by isovue M-300, and this can have dangerous effects on the kidneys. You should follow your doctor's advice about how much fluid you need to drink before and after the test.
You may need to take extra care with older adults in order to prevent dehydration. You may need to have your kidney function checked after receiving Isovue M-300. Some reactions to Isovue-M-300 can start 30–60 minutes after the first administration. You may be watched by your carers during this time. You want to be sure that you don't have any side effects or delayed reactions.
You may experience interference with medical tests up to 16 weeks after taking Isovue M-300. Inform any doctor that treats you about the recent use of this medication.
What happens if I miss the dose?
You will not have a schedule of doses since Isovue-M-300 is only used during radiologic tests.
What happens if I overdose?
Call 1-800-222-1222 for poison help or seek immediate medical attention.
What should be avoided?
You should not become dehydrated in the first few days following Isovue M-300. During this period, call your doctor if any nausea or diarrhea occurs. You should follow your doctor's advice on the type and amount of fluids to drink.
Interaction with other drug
Inform your physician of all current medications you are taking, such as:
- Diabetes medicine that contains metformin. (Glucophage Glucovance Actoplus Met prandimet Avandamet Janumet Kazano Invokamet Jentadueto Xigduo Synjardy Metaglip and others).
This list is incomplete. Isovue M-300 may be affected by other drugs, such as vitamins and herbs. This list does not include all drug interactions.
