What is Iodixanol?
Iodixanol belongs to a class of drugs known as radiopaque contrast agents (RAY DEE OOH PAYK). Iodixanol is a radiopaque contrast agent that contains iodine. Contrast agents that are radiopaque allow the blood vessels, organs, and non-bony tissue to be more easily seen on a CT scan.
Iodixanol can be used to diagnose disorders in the brain, blood vessels, heart, kidneys, and other organs. Iodixanol can be used in other ways not mentioned in this guide.
Side effects of Iodixanol
If you experience symptoms of an allergic reaction, such as hives, difficulty breathing, swelling on your face or in your throat, or a severe reaction to your skin (fever or sore throat, pain in the eyes, or skin irritation), or if your skin has rashes that are red or purple and cause blistering or peeling, seek emergency medical attention.
If you experience a severe drug reaction, seek medical attention. This can include a skin rash, fever, or flu-like symptoms. Other symptoms may include muscle aches or weakness, unusual bruises, or yellowing.
Iodixanol may cause serious side effects. If you experience:
- A feeling of lightheadedness, as if you could pass out.
- Weight gain and swelling are rapid, but there is little or no urination.
- Difficulty breathing
- A seizure (convulsions);
- Symptoms of thyroid disease include extreme tiredness, dry skin, stiffness or joint pain, muscle weakness or pain, hoarseness in voice, sensitivity to cold temperatures, and weight gain.
- Heart attack symptoms: chest pain or pressure, spreading pain to your jaw and shoulders, nausea, or sweating.
- Signs of a Stroke: sudden numbness (especially on one side), severe headache, slurred or shaky speech, or problems with vision, balance, or coordination;
- Signs of a blood clot in the lungs: chest pain, sudden hack, wheezing, and rapid breathing
Iodixanol can cause a number of side effects.
- When the medicine is injected, you may feel a warm or painful sensation.
- Dizziness, spinning sensation;
- Feeling of tingling or numbness;
- Vision changes
- Sleep problems (insomnia);
- Headache, migraine;
- Chest pain;
- Nausea, vomiting, diarrhea;
- Agitation, anxiety, and nervousness;
- Itching on the skin rash
- Changes to your sense of smell or taste.
There may be other side effects. For medical advice on side effects, call your doctor. The FDA can be contacted at 1-800-FDA-1088 to report side effects.
Similar/related drugs
Iohexol, barium sulfate, Omnipaque 350, Omnipaque 300, datscan, Volumen, Ultravist
Warnings
Iodixanol shouldn't be given to children who have recently used laxatives (stool softeners) or have not eaten well.
Before you take this drug
Iodixanol shouldn't be given to children who have recently used laxatives (stool softeners) or have not eaten well. Inform your doctor if there has ever been a reaction to any other contrast agent.
Tell your doctor about any of the following to ensure that iodixanol will not harm you:
- Liver or kidney disease
- Heart diseases, including congestive cardiac failure.
- A history of strokes, blood clots, or coronary arterial disease
- Food or drug allergy;
- Epilepsy
- Sickle-cell anemia
- Diabetes;
- An active infection;
- A weak immune system, caused by illness or certain medicines.
- An autoimmune disease such as rheumatoid arthritis, lupus, or psoriasis.
- Pheochromocytoma
- Multiple myeloma; bone cancer
- Thyroid disorder, including cancer.
Iodixanol is not known to harm unborn babies. Inform your doctor if you are pregnant.
There is no way to know if iodixanol can pass into breast milk or if it will affect a nursing baby. Do not breastfeed for 10 hours following iodixanol. Throw away any milk collected by a breast pump. Do not give it to your child.
How to take Iodixanol?
Iodixanol can be injected through an IV into a vein. This injection will be given by a healthcare provider just before the radiologic test.While you receive iodixanol, you may be prescribed medication to help prevent certain side effects.If you experience any pain or swelling when the iodixanol injection is administered, tell your carer.
Drink more fluids both before and after the radiologic test. Iodixanol may cause dehydration, which could have dangerous effects on the kidneys. You should follow your doctor's advice about how much fluid you need to drink before and after the test.You may need to take extra care with older adults in order to prevent dehydration. You may need to have your kidney function checked after receiving iodixanol.
Iodixanol may interfere with some medical tests up to 16 weeks after treatment. Inform any doctor that treats you about your recent use of iodixanol. Iodixanol may make radioactive iodine ineffective for people with thyroid cancer. This effect may last up to eight weeks after receiving iodixanol. You should tell your doctor if radioactive iodine I-131 and I-123 are scheduled for treatment.
What happens if I miss the dose?
You will not have a schedule of doses since iodixanol is only used during radiologic tests.
What happens if I overdose?
Call 1-800-222-1222 for poison help or seek immediate medical attention.
What should be avoided?
Avoid becoming dehydrated in the first few days following iodixanol treatment. If you experience any nausea or diarrhea, call your doctor. You should follow your doctor's advice on the type and amount of fluids to drink.
Interaction with other drug
Tell your doctor all of your current medications, including:
- Metformin is available in many forms (glucophage glucovance). Actoplus Met prandimet avandimet Janumet Kazano Invokamet Jentadueto Xigduo Synjardy Metaglip and others).
This list is incomplete. Iodixanol may interact with other drugs, such as prescription and over-the-counter medicines, vitamins, and herbal products. This medication guide does not list all possible interactions.
