What is Insulin aspart (protamine) and insulin aspart?
Insulin works by lowering the levels of sugar in the blood. Insulin Aspart Is a fast-acting form of insulin. Insulin aspart protamine has an intermediate action. This combination of insulin begins to work 10 to 20 minutes following the injection. It reaches its peak in two hours and continues to function for up to twenty-four hours.
Combination insulin aspart/insulin aspart protamine medicine is used to control blood sugar in adults with type 1 or type 2 diabetes.This medication guide does not list all possible uses for insulin aspart or insulin aspart protamine.
Side effects of Insulin aspart (protamine) and insulin aspart
If you experience any of the following symptoms, you should seek emergency medical attention: swelling or redness where an insulin injection was administered; itchy skin all over your body; difficulty breathing; wheezing or rapid pulse; sweating or feeling as if you may pass out; swelling on your tongue or in your throat.
Both insulin aspart and protamine can cause serious side effects. If you experience:
- Fluid retention: weight gain, swelling of the hands or feet, or feeling short-breathing;
- Low sodium, leg cramps, constipation, increased thirst and urination, numbness, tingling or numbness, muscle weakness, or a limp feeling
Side effects of insulin aspart or insulin aspart protamine include:
- Low potassium
- Mild skin rash;
- The skin may become thicker or hollower where the medication was injected.
There may be other side effects. For medical advice on side effects, call your doctor. The FDA can be contacted at 1-800-FDA-1088 to report side effects.
Warnings
Do not share a syringe or injection pen with anyone else, even if the needle has been changed.
Before you take this drug
This medicine should not be used if you have an episode of hypoglycemia or low blood sugar.The use of this medicine by those under 18 is not recommended.
Tell your doctor about any of the following:
- Liver or kidney disease
- Low potassium levels in the blood (hypokalemia)
Inform your doctor if, in addition to insulin, you are taking pioglitazone and rosiglitazone. These medications may be combined with glimepiride and metformin. You may be at greater risk for serious heart problems if you take certain diabetes medications while using insulin.
Inform your doctor if you are pregnant or nursing.If you're pregnant or plan to become pregnant, follow your doctor's advice about insulin.
How to take Insulin aspart (protamine) and insulin aspart?
Read and comply with any instructions or guides included with your medication. Follow the directions on the label.
The medicine is injected into the skin. You may be taught how to use the medicine by a healthcare provider. This medicine should not be injected into a vein or muscle. This type of insulin must not be used with an insulin pump or mixed with any other insulin.Please read and follow all instructions for use that come with your medication. If you do not understand the instructions, ask your doctor or pharmacist.
Only prepare an injection when you're ready to administer it. This medicine should be white and cloudy. If the medicine appears clear or contains particles, do not use it. For new medication, call your pharmacist.
You should use insulin at the same time as you eat.
- If you have diabetes type 1, take this medication within 15 minutes of starting a meal.
- If you have type 2 diabetes, use this medicine 15 minutes before or following a meal.
Use only the pen that came with your medicine if you are using an injection pen. Attach a fresh needle to each injection.Do not share a syringe or injection pen with anyone, even if it has been cleaned. This can lead to the spread of infection or disease.This medicine should not be injected into damaged skin that is bruised, scaly, or pitted.
If you have hypoglycemia, you may feel very hungry or dizzy. You might also be confused, anxious, or If you want to treat hypoglycemia quickly, consume or drink something that will provide sugar quickly (such as fruit juice, hard candies, crackers, or raisins).
In the event of severe hypoglycemia, your doctor may prescribe a glucagon injectable kit. Make sure that your family and friends are familiar with how to administer this injection in case of an emergency.Watch for signs such as increased thirst and urination.Stress, illness, surgery, or alcohol consumption can affect blood sugar levels. Consult your doctor before changing the dose or schedule of your medication.
This medicine should be kept in the original container, away from heat and sunlight. Store insulin away from the cooling element of a fridge, or do not freeze it. Do not use any frozen insulin.
Store this medicine in its original, unopened packaging (not for use).
- Use within the expiration date.
- Store the vial at room temperature and use it within 28 days.
This medicine is not suitable for storage once it has been opened.
- Store vials in the refrigerator or at room temperature. Use within 28 days.
- Use the pen within 14 days. Store at room temperature. Store the pen without a needle.
Only use a needle or syringe once, and then store them in an "as sharps" container that is puncture-proof. Be sure to follow local or state laws on how to properly dispose of the container. Keep the container out of reach of pets and children.
Details on dosage
Adult dosage for diabetes type 1:
Individualise dosage based on glucose treatment goals, metabolic needs, and eating habits.
Important Limitation on Premix Insulin: This insulin has a fixed ratio of intermediate-acting and rapid-acting (rapid) insulins. The premix consists of 30% insulin aspart and 70% insulin aspart.
Usual dose: Administer the prescribed units subcutaneously 15 minutes prior to meal ingestion.
Typically, the dose is given twice daily. Each dose covers two meals or one meal and a snack.
Comments:
The total daily insulin requirement is estimated at between 0.5 and 1 unit/kg/day.
The duration of action can vary depending on the dose, injection site, and temperature.
Use: To improve the glycemic level in diabetic patients.
Adult dosage for diabetes type 2:
Individualise dosage based on glucose treatment goals, metabolic needs, and eating habits.
Important Limitation on Premix Insulin: This insulin has a fixed ratio of intermediate-acting and rapid-acting (rapid) insulins. The premix consists of 30% insulin aspart and 70% insulin aspart.
Usual dosage: Administer the prescribed units subcutaneously 15 minutes prior to or after meal ingestion.
Usually dosed twice daily, with each dose intended to cover two meals or one meal and a snack.
Comments:
The duration of action can vary depending on the dose, injection site, and temperature.
Use: To improve the glycemic level in diabetic patients.
What happens if I miss the dose?
You may not have a dosing regimen because insulin aspart or insulin aspart protamine are used with meals. You should eat within 15 minutes of using this insulin. Don't use extra medication to make up for a missed dosage.
What happens if I overdose?
Call the Poison Help Line at 1-800-222-1222 or seek emergency medical care. An insulin overdose can lead to life-threatening hypoglycemia. The symptoms include drowsiness, confusion, blurred sight, difficulty speaking, muscle weakness, and jerky movements.
What should be avoided?
Do not drive or operate machinery until you have determined how the medicine will affect you.Check the label of your medication before you inject it to avoid any mistakes.Avoid alcohol. Alcohol can cause low sugar levels and interfere with diabetes treatment.
Interaction with other drug
Other medicines can also affect your blood glucose, and some can increase or decrease insulin's effects. You may also experience fewer hypoglycemic symptoms when you take certain drugs, making it more difficult to detect low blood sugar. Inform your healthcare providers of all the medicines you are taking and those you plan to take. You can include prescription and over-the-counter medicines, vitamins, and herbal products.
