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Generic name: carbinoxamine (pronounced car-binox-ah-meen) Brand names include Karbinal ER and Ryvent. Histex PD and Histex CT are also available.
Dosage Forms: oral liquid (4 mg/5 ml), orally suspended, extended release (4 mg/5 ml), orally tablet (6 ml)
Drug class: antihistamines

What is Carbinoxamine?

Carbinoxamine, an antihistamine, is used to treat symptoms such as a runny or stuffed-up nose, sneezing, and other allergy symptoms. Carbinoxamine can be used by adults and children older than 2 years. Carbinoxamine can be used in other ways not mentioned in this guide.

Side effects of Carbinoxamine

If you experience any of the following signs and symptoms of an allergic reaction: difficulty breathing, hives or facial, lip or throat swelling. Seek immediate medical care.

Carbinoxamine may cause serious side effects. Call your doctor immediately if:

  • A feeling of lightheadedness, as if you could pass out.
  • Little or no urination
  • Tightness in the chest;
  • If you feel your heart pounding or your chest fluttering, then it is a sign that you are experiencing a cardiac arrest
  • Pale skin is prone to bleeding or bruising.

Older adults may experience more side effects, such as confusion and dizziness.

Side effects of carbinoxamine include:

  • Dry mouth, nose, or throat
  • Drowsiness, dizziness;
  • Loss of coordination
  • Upset stomach.

There may be other side effects. Call your doctor if experiencing side effects; for reporting purposes contact the FDA at 1-800-FDA-1088.


Do not use it other than as directed. Inform your doctor of any other medications you are taking or if you have allergies or other medical conditions.

Before you take this drug

If you have an allergy to carbinoxamine, do not use it. Use carbinoxamine only if you are also taking an MAO-inhibitor such as linezolid (isocarboxazid), phenelzine, or tranylcypromine. Use by children under 2 years of age is not recommended.

Inform your physician of any of the following issues:

  • Glaucoma;
  • A stomach ulcer
  • A blockage of your digestive tract, such as the stomach or intestines;
  • A thyroid disorder
  • Heart problems High blood pressure
  • Liver or kidney disease
  • Asthma, or sulfite allergies?
  • An enlarged prostrate
  • Urination problems can be caused by a number of factors.
  • Low blood pressure.

While using carbinoxamine, you should not breastfeed. Inform your doctor that you are expecting.

How to take carbinoxamine?

Read all instructions or guides that come with your medication and follow all directions. Follow the directions on the label.

When giving carbinoxamine, follow all instructions. Never use this medicine to put a child to sleep. Shake the orally dispersible suspension. Use the syringe provided or a dosage-measuring tool (not a spoon) to measure a dose. If your symptoms don't improve or worsen, call your doctor. Store away from moisture, heat, and light at room temperature.

What happens if I miss the dose?

Carbinoxamine can be used as needed. You should not take any missed doses if you have a regular schedule. Never use two doses in one go.

What happens if I overdose?

Call the Poison Help Line at 1-800-222-1222 or seek emergency medical care. Overdoses can be deadly, especially for children.

Overdose symptoms include extreme drowsiness, restlessness, hallucinations, and dilated pupils.

What should be avoided?

Do not drive or engage in hazardous activities until you are familiar with the effects of carbinoxamine. You may be unable to react properly. Avoid alcohol consumption. Before using any other cold or cough medicines, check with your doctor.

Interaction with other drug

Before taking any other medications that may cause drowsiness, consult your doctor or pharmacist (e.g., opioid medication, muscle relaxers, medicines for anxiety, seizures, etc.). Inform your doctor of all the medicines you take. Included are prescription and over-the-counter medicines, vitamins, and herbal products. This list does not include all possible interactions.




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