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Hydrocodone and ibuprofen

Generic name: hydrocodone and ibuprofen [HYE-dro-KOE-done-and-EYE-bue-pro-fen]
Brand names: Vicoprofen (Ibudone), Reprexain (Xylon 10), and Reprexain (Vicoprofen).
Oral tablet: (10 mg–200 mg; 5 mg–200 mg; 7.5 mg–200 mg)
Drug class: narcotic analgesic combinations

What is Hydrocodone and ibuprofen?

Hydrocodone is an opioid pain medication. Ibuprofen, a nonsteroidal analgesic drug (NSAID), is a form of This combination medicine that can be used to relieve severe pain for a short time.This medication guide does not list all possible uses of ibuprofen and hydrocodone.

Side effects of Hydrocodone and ibuprofen

If you experience symptoms of an allergic reaction, such as hives, difficulty breathing, swelling on your face or in your throat, or a severe reaction to your skin (fever or sore throat with burning, pain in the eyes, or skin rash, which is red or purple and blisters or peels), seek emergency medical attention.If any of these symptoms arise, seek immediate medical care.If you take opioid medicine, it can cause your breathing to slow down or stop. Death may result. If you have long pauses in your breathing, blue lips, or are hard to awaken, someone caring for you may want to give you Naloxone and/or seek immediate medical attention.

Ibuprofen and hydrocodone can cause serious side effects. If you experience:

  • Sighing or weak breathing; a slow heartbeat; breathing that stops while sleeping
  • Rapid weight gain and swelling
  • A skin rash is a rash on the skin, regardless of how mild it may be.
  • Signs of stomach bleeding include bloody or tarry stool, vomiting that looks like coffee, or coughing up blood.
  • Dark urine, fatigue, nausea, diarrhea, upper stomach pain, and flu-like symptoms are all signs of liver disease.
  • Kidney problems: little or no urine, swelling of the feet or ankles, and feeling tired or breathless;
  • Low cortisol levels can cause nausea, vomiting, or worsening fatigue or weakness.
  • High levels of serotonin can cause agitation, hallucinations, fever, sweating, and shivering. Rapid heart rate. Muscle stiffness and twitching. Loss of coordination. Nausea.

Severe breathing problems are more common in elderly adults, especially those with wasting syndrome and chronic breathing disorders.

Side effects of ibuprofen and hydrocodone include:

  • Dizziness, drowsiness;
  • Stomach pain, nausea and vomiting, and heartburn;
  • Diarrhea; constipation

There may be other side effects. For medical advice on side effects, call your doctor.Contact the FDA by calling 1-800-FDA-1088 in order to report side effects.

Warnings

Misuse of opioid medication can cause addiction, overdose, or death. Store the medication away from others.Hydrocodone and ibuprofen taken during pregnancy can cause severe withdrawal symptoms for the newborn.You may experience fatal side effects if you combine this medication with alcohol or other drugs that make you drowsy or cause breathing problems.

Before you take this drug

This medicine should not be used if:

  • Severe asthma or breathing problems
  • A blockage of the intestines or stomach

Ibuprofen may increase the risk of a fatal stroke or heart attack. This medicine should not be taken before or immediately after a heart bypass operation. Ibuprofen can also cause fatal stomach or intestinal bleeding.

Inform your physician of any of the following issues:

  • Sleep apnea is a breathing problem.
  • A head injury, brain tumor, or seizure;
  • Liver or kidney disease
  • Heart problems or heart attacks;
  • You may have problems with your thyroid, gallbladder, or pancreas.
  • Urination problems can be caused by a number of factors.
  • Mental illness, drugs, or alcohol Abuse can be a result of mental illness or addiction to drugs or alcohol.

Do not take an NSAID in the last 20 weeks before delivery. It can be harmful to the baby. Your baby may become dependent on opioids if you take them while pregnant. Withdrawal symptoms can be life-threatening for the newborn. Babies who are born addicted to habit-forming medicines may require medical care for several weeks.Before using this medication, ask your doctor if you are breastfeeding. If you notice a nursing infant is drowsy or breathing slowly, tell your doctor.

How to take Hydrocodone and ibuprofen?

Read all the instructions on the label of your medication and follow them. Use ibuprofen and hydrocodone only in the prescribed amounts. If you are feeling a greater urge to take this medication, tell your doctor.Do not share this medication with anyone, especially if they have a history of drug abuse. Misuse can lead to addiction, overdose, or death. Store the medicine in a safe place that others cannot access. Selling or giving away this medication is unlawful.Store products away from moisture and heat at room temperature.

Keep leftover opioid medications out of the reach of children. One dose of this medication can be fatal for someone who uses it incorrectly or accidentally. You should ask your pharmacist about a drug disposal program. If there isn't a take-back program available, flush any unused medication down the toilet.

Details on dosage

Adult dose for pain:

Take one tablet every 4 to 6 hours as needed.
Maximum dose: five tablets per 24 hours.
The duration of treatment is usually less than 10 days.
Comments:
For each patient, the lowest dose or the longest interval between doses should be used.
Each tablet contains a combination of 200 mg of ibuprofen and hydrocodone in doses of 2.5, 5, 7, or 10mg.
This drug is only to be used in patients who have been unable to tolerate alternative treatments, for whom it is not expected that they will tolerate them, or for whom other treatment options are inadequate or do not provide adequate pain relief.
Use: To treat acute pain that is severe enough to need an opioid analgesic but for which other treatments are ineffective.

The usual pediatric dose for pain:

16 years and older
Take one tablet every four to six hours as required.
Maximum dose: five tablets per 24 hours.
The duration of treatment is usually less than 10 days.
Comments:
For each patient, the lowest dose or the longest interval between doses should be used.
Each tablet contains a combination of 200 mg of ibuprofen and hydrocodone in doses of 2.5, 5, 7, or 10mg.
This drug is only to be used in patients who have been unable to tolerate alternative treatments, for whom it is not expected that they will tolerate them, or for whom other treatment options are inadequate or do not provide adequate pain relief.
Use: To treat acute pain that is severe enough to need an opioid analgesic but for which other treatments are ineffective.

What happens if I miss the dose?

You are unlikely to miss a dosage of hydrocodone or ibuprofen, as they are used to treat pain. If it's almost time to take your next dose, skip any missed doses. Never take two doses in one go.

What happens if I overdose?

Call the Poison Help Line at 1-800-222-1222 or seek emergency medical care. An accidental overdose is deadly, especially if it occurs in a child or a person who has taken the medication without a prescription.You may be advised by your doctor to carry naloxone with you (a medicine that reverses an overdose). If you stop breathing or don't awaken, a person who cares for you can administer naloxone. You must still call for emergency medical assistance, and your caregiver may have to perform CPR on you while they wait.Naloxone can be purchased at any local pharmacy or health department. You should make sure that anyone who cares for you is aware of where and how you store your naloxone.

What should be avoided?

Do not drive or engage in hazardous activities until you have a better understanding of how ibuprofen and hydrocodone will affect you. Dizziness and drowsiness may cause accidents or serious injuries.Don't drink alcohol. Side effects and death can occur.They may contain ingredients similar to ibuprofen (such as a data-type="auto" href="https://www.drugs.com/mtm/ketoprofen.html">ketoprofen/a>, a data-type="auto" href="https://www.drugs.com/aspirin.html">aspirin/a>, or if you are experiencing a cold or flu like These medicines may contain similar ingredients to ibuprofen, such as aspirin or ketoprofen.

Interaction with other drug

If you stop or start taking certain medicines, you may experience breathing problems or withdrawal. You should tell your doctor if other medicines are being used, such as an antifungal, blood pressure or heart medication, seizure medicine, HIV/hepatitis C, or a medication to treat HIV.

Opioid medications can interact with other drugs, causing dangerous side effects and even death. Tell your doctor if you use:

  • Medications, bronchodilator asthma/COPD medicine, or diuretics ("water pills");
  • Medicines for motion sickness or irritable intestine syndrome
  • Other opioids—opioid-pain medicine or prescription cough medicine
  • A sedative such as Valium—diazepam (alprazolam), lorazepam (lorazepam), Xanax (Klonopin), Ativan, and others.
  • Sleeping pills, muscle relaxants, medicines to treat mental disorders, mood disorders, or other drugs that slow down breathing
  • Drugs that increase serotonin in the body, such as stimulants, medicines for depressive disorders, Parkinson’s disease, or migraine headaches

This list is incomplete. Hydrocodone, ibuprofen, and other drugs can interact, including prescription, over-the-counter, vitamins, and herbal products. This list does not encompass all potential interactions.