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Periogard (oral rinse)

Generic name: chlorhexidine gluconate (oral rinse) [klor-HEX-i-deen]
The brand names are: Paroex, Peridex, PerioChip, and Periogard.
Classifications of drugs: antiseptics and germicides; mouth and products for the throat.

What is Periogard?

Periogard is a mouthwash that kills germs, which reduces the amount of bacteria that can be found in the mouth. Periogard helps treat gum disease (swelling, redness, swelling, bleeding gums). The medication is typically recommended by a dentist.

Periogard is not a treatment for all forms of gingivitis. It is only used for the conditions that your dentist recommended it for. Don't give this medication to someone else, even if they share the same gum problems as you do. Periogard could also be used for other purposes that are not mentioned in this guide.

Side effects of Periogard

Periogard is a common but severe allergic reaction that could be life-threatening. Seek medical attention immediately in the event that you exhibit any of these symptoms, warning signs of an allergic reaction such as hives, severe skin rash, breathing difficulties, wheezing or breathing, cold sweats, feeling lightheaded, and swelling of your lips, face, and tongue.

Periogard can cause severe adverse reactions. Consult your doctor immediately if you suffer from:

  • White patches of sores or white spots in the mouth or around your lips.
  • mouth ulcers mouth ulcers
  • The salivary glands of your mouth are swelling (underneath the jaws).

Common adverse consequences of Periogard can include:

  • mouth irritation;
  • tooth staining
  • Dry mouth;
  • uninspiring or unpleasant taste that you get in your mouth.
  • less taste sensation.

This isn't a complete list of possible side effects, and other side effects could occur. Contact your doctor to seek medical advice on adverse effects. You can report symptoms to the FDA at 1-800-FDA-1088.


Periogard could trigger an uncommon but serious allergic reaction that can be potentially life-threatening. Get emergency medical assistance if you experience an allergic reaction that is severe, such as hives or a skin rash, wheezing, difficulty breathing, chills, or feeling lightheaded or swollen in your mouth, lips, face, or throat.

Don't give this medicine to children or teens without consulting a physician. Periogard can cause extreme irritation or chemical burns for children.

Before taking this medication

It is not recommended to use this medicine if you are allergic to Periogard. If you suffer from periodontal diseases, you may require specific treatments while using Periogard.

Don't give this medicine to your child or teenager without the advice of a doctor. This medication could cause severe burns or irritation for children under the age of Periogard is not permitted for use by people younger than 18 years of age.

It is unclear if this medication could affect a newborn baby. Inform your doctor if you are expecting or planning to be pregnant. It isn't known if chlorhexidine is a gluconate that gets into breast milk or if it affects the nursing infant. Inform your doctor if you are breastfeeding.

How to take Periogard?

Follow the directions on the prescription label. Don't use Periogard in smaller or larger quantities or for longer than the recommended time. Cleanse the mouth using Periogard two times a day, after you have cleaned your teeth. Make sure you measure your dosage using the cup that comes with the prescription. The medicine should be sprayed into your mouth for a minimum of 30 seconds and then poured out. Do not ingest the mouthwash.

Do not mix water with your oral rinse. Avoid washing your mouth with water or any other mouthwashes immediately after you have used Periogard. Periogard can leave a bitter flavor in the mouth. Avoid rinsing your mouth to eliminate the taste following the use of the medicine. The medicine could be rinsed away, which can reduce the effectiveness of the medication.

Take this medicine for the prescribed duration of time. The symptoms could improve after your gingivitis completely disappears. Periogard does not treat fungal or viral infections like cold sores, canker sores, or oral thrush (yeast infection). Make an appointment with your dentist every six months to ensure the prevention of gum and tooth decay. Keep Periogard in a cool, dry place, away from heat and humidity.

Do I be concerned if I miss a dose?

Take the missed dose immediately when it is remembered; however, be sure to brush the teeth before. Avoid your missed dosage if it's nearing the time for the next dose. Don't use any extra medication to replace the missed dose.

What will happen if I take excessively?

For medical emergencies, seek emergency treatment or contact the Poison Help Line at 1-800-222-1222, in particular if a child has taken more than 4 ounces of Periogard.

Chlorhexidine can be abused, and overdoses could occur only if the medication was swallowed. The symptoms of an overdose could be nausea or stomach pain, as well as the appearance of being drunk.

What should be avoided?

Periogard can stain teeth and denture restorations to your teeth, as well as your tongue or even the interior of your mouth. Consult your dentist about methods to get rid of any staining that may be present on the surfaces. They may be more difficult to remove from false teeth with scratches on their surfaces. Avoid drinking, eating, and brushing your teeth immediately after you have taken this medicine. Do not use any other mouthwash unless your doctor has instructed you to.

Interaction with other drugs

It's unlikely that other medications you take by mouth or inject will have any influence on Periogard. However, there are many drugs that interact with each other. Inform your health professionals about the medicines you use, such as prescription and over-the-counter drugs, vitamins, and herbal remedies.