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Homatropine Ophthalmic

Generical name: homatropine ophthalmic [hoe-ma-TROE-peen]
The brand names are: Homatropaire, Isopto Homatropine
Dosage forms: ophthalmic solution (5%)
Drug class: Mydriatics

What is Homatropine Ophthalmic?

Homatropine relaxes the muscles of the eye's iris (the colored area) in your eyes. Relaxing these muscles will help dilate or expand your pupils.

Homatropine ophthalmic (for the eye) can be used to treat an eye disease known as uveitis. Homatropine ophthalmic may also be used to dilate your pupils prior to an eye exam or to reduce pressure in the eye following an eye surgical procedure.

Homatropine ophthalmology can also be employed for other purposes that are not covered in this guideline.

Side effects of Homatropine Ophthalmic

Contact a medical professional immediately. If you are experiencing symptoms or warning signs of a reaction, like hives, trouble breathing, or swelling of your lips, face, tongue, throat, or face, While the chance of having adverse side effects can be very low when homatropine has been used in the eyes, complications may occur if the medication is absorbed into the bloodstream.

Homatropine ophthalmic can cause severe adverse reactions. Contact your doctor immediately when you experience:

  • Eye swelling, redness, or drainage
  • Eyes that are puffy or red.
  • The confusion, agitation, or
  • Strange thoughts or behaviors.

Common side effects of homatropine can be:

  • Burning and stinging after applying the eye drops
  • Dry mouth, increased thirst,
  • Increased eye sensitivity to bright light.

This is not a comprehensive list of possible side effects, and other side effects could occur. Contact your doctor for advice regarding medical adverse effects. You can report any side effects to the FDA at 1-800-FDA-1088.


It is not recommended to use homatropine eye drops if you suffer from glaucoma.

Before taking this medication

This medication if you have an allergy to homatropine, or you are:

  • Glaucoma, or
  • If your eye doctor observes signs of changes to your eyes, these may be signs of glaucoma.

It isn't known if this medication will affect a newborn baby. Consult your physician if you are expecting.

It isn't known if homotropine ophthalmic is passed into breast milk or if it is harmful to the baby who is nursing. Consult your physician if you are breastfeeding a child.

What should I do with homatropine ophthalmic?

Follow all the instructions on the prescription label. Don't use homatropine eye drops in greater or lesser quantities or for longer periods than recommended.

Do not take this medicine when using contact lenses. Homatropine is an ophthalmic that may contain a preservative, which can cause the discoloration of soft contact lenses. You should wait at least 15 minutes after taking this drug before placing contacts. To treat uveitis, you may have to apply homatropine or ophthalmic cream once every 3–4 hours. Wash your hands thoroughly prior to applying these eye drops.

To apply drops to the eyes:

  • Adjust your head slightly and then pull the lower eyelid, creating small pockets. Keep the dropper in front of your eye, with the tips facing downward. Take a look upwards at the sky and then away from your dropper, and squeeze one drop.
  • Keep your eyes closed for two or three minutes with your head tilted down without blinking, blinking, or squinting. Make sure to gently press your finger on the inside of your eye for approximately one minute to prevent the fluid from leaking into the tear duct.
  • Make sure you only use the number of drops that your doctor has advised. If you take several drops at once, you should wait approximately 5 minutes between the drops.
  • At least 10 minutes prior to using or using any eye drop or other that your physician has recommended.

Don't touch the tip of your eyedropper or put it directly in your eye. Drops that are contaminated can affect your eyes and could result in serious vision issues.

Don't use eye drops if it appears that the liquid has changed color or contains particles. Contact your pharmacist to inquire about the latest medication.

Keep it at room temperature, far from heat and moisture. Avoid freezing. Close the bottle when not being used.

Details on dosage

Usual Adult Dose for Refraction:

Take 1 to 2 drops of the solution into the eye(s) at a time; repeat the procedure in 5 to 10 minutes, if necessary.

The medication has not been deemed FDA-approved. US FDA as safe and effective, and the labeling hasn't been accepted to be approved by authorities at the US FDA.

Usual Adult Dose for Uveitis:

Drop 1 or 2 drops in the eye(s) each time for 3 to 4 hours.

This drug has not been confirmed to be safe and effective by the FDA. US FDA as safe or effective. The labeling is not accepted to be approved by authorities at the US FDA.

Usual Pediatric Dose for Refraction:

For children older than 3 months: inject up to 2 drops of the drug into the eye(s) once. You can repeat the procedure in 5 to 10 minutes if necessary.

The medication has not been deemed safe and effective by the FDA. US FDA in a way that is safe and effective, and the labeling is not accepted to be approved by authorities at the US FDA.

Usual Pediatric Dose for Uveitis:

Over 3 months: Put 1–2 drops in the eye(s) each time for 3–4 hours.

The drug has not been confirmed to be safe and effective by authorities at the US FDA, and the labeling hasn't been accepted to be approved by authorities at the US FDA.

Do I be concerned if I miss a dose?

Take the dose you missed when you remember. Do not take any missed doses if it's close to the time for the next dose. Don't take extra medication to make up for the missed dose.

What will happen if I take excessively?

For medical emergencies, seek emergency treatment or contact the Poison Help Line at 1-800-222-1222 if you have accidentally swallowed the medicine.

What should be avoided?

Homatropine ophthalmic can cause blurred vision and could affect your thinking or reaction. Be cautious when driving or engaging in any activity in which you need to stay aware and in a position to clearly see. Homatropine eye drops could make your eyes more sensitive to sunlight. Be sure to protect your eyes when you're outside in the sun

Interaction with other drugs

It's not likely that other medications you take in the form of injections or orally could affect the homatropine in your eyes. However, many medications can interact with each other. Be sure to inform your health care providers about the medications you are taking, which include medications that are prescribed and available over the counter, vitamins, and herbal remedies.