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Generic Name: Isotretinoin (oral) [EYE-so-TRET-i-noyn]
The Brand Names are: Absorica, Absorica LD, Accutane, Amnesteem, Claravis,… Show the nine brands
Classification of Drugs: Miscellaneous uncategorized agents

What is Zenatane?

Zenatane is a type of vitamin A that can be used for treating severe acne that has not been treated with other methods, which include antibiotics.

Zenatane is only available from an accredited pharmacy that is part of the iPLEDGE program meme, which is a specific program meme.Zenatane could also be used to treat conditions that are not covered in this guide.

Side effects of Zenatane

Seek medical attention immediately. If you notice symptoms warning signs of an allergic response (hives, breathing problems, and swelling in your throat or face) or an extreme skin reaction (fever, throat soreness, eye burning, ache, and a red or purple skin eruption with peeling and blisters),

Zenatane can cause serious adverse reactions. Stop taking Zenatane and consult your physician immediately if you experience:

  • Issues with your hearing or vision;
  • Muscles and joint discomfort; bone pain lower back pain;
  • Increased thirst and more frequent urine production;
  • Hallucinations (seeing or hearing things that aren't real);
  • Signs of symptoms of depression—unusual mood swings mood swings, crying spells, feelings of self-doubt, loss of interest in things that you used to enjoy, sleep issues that have not improved thoughts of hurting yourself
  • Indications of pancreas or liver problems: lack of appetite, stomach discomfort (that could extend to your back), nausea or vomiting, fast heart rate, dark urine, yellowing of the eyes (yellowing on the eyes or skin);
  • Severe stomach issues—severe stomach pain and chest discomfort, discomfort during taking a swallow, heartburn, diarrhea, or rectal bleeding with bloody or tarry stool; or
  • Increased pressure in the skull: severe headaches, ringing of the ears, nausea, dizziness, eye problems, eye pain

Common negative side effects of zenatane can include:

  • Dryness of your lips, skin, and eyes (you may experience nosebleeds);
  • Vision issues;
  • Headache, back pain, joint pain, muscle problems;
  • Skin reactions
  • Signs of a cold like congestion, sneezing, and a sore throat.

This is not a comprehensive list of all the side effects. Other side effects could be present. Consult your physician for advice regarding medical effects. You can report any symptoms to the FDA at 1-800-FDA-1088.

Similar or related drugs

Doxycycline, Clindamycin topical, Topical Erythromycin, Tetracycline, and Tazorac


Zenatane in just one dose could cause serious birth defects or even the death of a child. Don't use zenatane when you're pregnant or have the potential to be pregnant.

It is necessary to have a positive pregnancy test prior to taking Zenatane. Additionally, you will be required to take two forms of contraceptives to avoid pregnancy while taking this medication. Stop taking this medicine and contact your physician immediately if you believe you may be pregnant.

Before you take this drug

Zenatane could result in miscarriage, premature birth, birth defects that are severe, or even the death of a child in the event that a mother uses this medication prior to the time of conception or pregnancy. Even one dose of isotretinoin could cause serious birth defects in the baby's eyes, ears, face, skull, heart, brain, and Don't take this medicine if you are pregnant or have the potential to become pregnant.

For women: Unless you have been able to have your ovaries and uterus eliminated (total hysterectomy) or you have been in the menopausal phase for a minimum of 12 consecutive months and you are believed to be able to become pregnant, You must pass two negative pregnancy tests prior to when you begin taking Zenatane, prior to the time each prescription is filled, immediately after you have taken the last dosage of isotretinoin, and then a further 30 days after. Testing for pregnancy will be required under this iPLEDGE programme.

You must have a written agreement to use two different forms of birth control that begin 30 days prior to the date you begin taking Zenatane and end thirty days after the last dose. Primary and secondary forms of birth control need to be used in conjunction.

The most common birth control methods are:

  • Tubal ligation (tubes tied);
  • Vasectomy performed on male partners
  • An IUD (intrauterine device);
  • Oestrogen-containing birth control tablets (not miniature pills) and
  • Birth control patches for hormonal use include implants, patches, injections, or vaginal rings.

Other forms of birth control are:

  • A male latex condom that has or without spermicide
  • A diaphragm plus spermicide;
  • An upper cervical cap, as well as a spermicide.
  • A vaginal sponge that contains the spermicide.

Stop taking Zenatane and consult your physician immediately if you are experiencing unprotected sexual relations, if you have stopped using birth control, if your menstrual cycle is delayed, or if you suspect that you are pregnant. If you become pregnant while taking this medication, make sure you contact the iPLEDGE pregnancy registry at 1-866-495-654.

The absence of sexual contact (abstinence) can be the best method for keeping a woman from becoming pregnant.

Zenatane should not be used if you are allergic to it.

Speak to your doctor if you are ever diagnosed with:

  • Mental illness or depression
  • Asthma;
  • Liver disease;
  • Diabetes;
  • The heart condition (also known as the high level of cholesterol;
  • Osteoporosis or low bone mineral density
  • An eating disorder like eating disorders like anorexia;
  • A food or drug an allergy to a food, drug,
  • An intestinal disorder like an inflammatory bowel disorder or ulcerative colitis.

Do not breastfeed.

Not recommended for use by anyone less than 12 years old.

How to take Zenatane?

Follow the instructions on your prescription label and review all medication guides and instruction sheets. Follow the medication precisely as directed.

Each prescription of isotretinoin should be completed within 7 days from the day it was issued by your physician. You can receive no more than a 30-day supply of isotretinoin in one go.Always be sure to take Zenatane with at least a bottle of fluid. Don't chew or chew into the capsule. Suck it up whole.

Follow all instructions for using Zenatane, whether or not you eat.

Utilize Zenatane for the entire duration of the prescribed period. The acne might appear to get worse initially; however, it will soon get better.It is possible that you will need frequent blood tests.Do not share this medication with anyone else, even if they share similar symptoms to yours.Maintain at room temperature, far from heat, humidity, and light.

What happens If I miss a dose?

Don't miss the dose you missed; take the next dose at the normal time. Do not take two doses at the same time.

What happens if I overdose?

Take immediate medical attention, or contact the Poison Help line at 1-800-222-1222 for help. The signs of an overdose can include nausea, headache, dizziness, stomach pain, warmth or tingling sensations in your face, swelling and cracked lips, and a loss of equilibrium and coordination.

What should be avoided?

Don't take a vitamin, mineral, or supplement containing vitamin A, except if your physician recommends it.

Don't donate blood while you are taking Zenatane or for a minimum of 30 consecutive days following the time you stopped using it. Donated blood that is later transferred to a woman who is pregnant could result in birth defects for her child if the blood contains any amount of isotretinoin.

While taking Zenatane and for at least six months following the last dose, avoid using wax hair removal products or laser or dermabrasion treatments. The result of scarring could beZenatane can cause you to burn more quickly. Avoid tanning beds and sunlight. Protect yourself with protective clothes and sunblock (SPF 30 or greater) while you're outdoors.

Avoid driving and other hazardous activities until you understand how zenatane can affect your vision. Zenatane could affect your vision, particularly in the evening.

Interaction with other drugs

Discuss with your doctor all other medications, including:

  • Phenytoin;
  • John's wort (which may cause birth control pills to be less efficient);
  • Mineral or vitamin supplements;
  • Birth control pills that contain progestin only (mini-pills might not perform as well when used together with zenatane);
  • Steroid medicine,
  • A tetracycline antibiotic that includes doxycycline as well as minocycline.

This list isn't complete. Other drugs can interact with Zenatane, such as prescription and over-the-counter medicines, vitamins, and herbal products. The interactions of all drugs are listed here.



Prescription only

Pregnancy & Lactation

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