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Hexatrione (injection)

Generic name: triamcinolone (injection) [TRUE-am-SIN-oh-lone]
Brand names: Hexatrione, Kenalog-10, Kenalog-40, Kenalog-80, Zilretta
Drug class: glucocorticoids

What is Hexatrione?

Hexatrione, a steroid, is used for treating many types of inflammation, including severe allergic reactions, skin disorders, and severe colitis. It is also used to treat blood cell disorders as well as inflammatory eye conditions, lung disorders, and problems caused by low levels of adrenal gland hormones.Hexatrione can also be used to treat skin conditions caused by autoimmune diseases such as Lupus, Psoriasis, Lichen Planus, and others.The uses of triamcinolone injection vary between brands.Hexatrione can be used in other ways not mentioned in this guide.

Side effects of Hexatrione

If you experience any of the following symptoms of an allergic reaction, seek immediate medical attention: difficulty breathing, hives, swelling of the face, lips, or throat.

Hexatrione may cause serious side effects. If you experience:

  • After injection, increased joint pain, swelling, fever, and a general feeling of ill health
  • Blurred vision, tunnel vision, eye pain or seeing halos around lights may all indicate troubled visual acuity.
  • Unusual changes in mood or behavior
  • Feeling short of breath, swelling, and rapid weight gain
  • Stomach cramps, diarrhea, bloody or tarry stool, and rectal irritation
  • A sudden feeling of numbness or weakness on one side
  • A seizure (convulsions);
  • Severe headache; blurred vision; or pounding in the neck and ears
  • Increased pressure in the skull can cause severe headaches, ringing ears, nausea, vision issues, or pain behind your eye.
  • Signs of low adrenal hormones include flu-like symptoms such as headaches, depressive feelings, fatigue, nausea, diarrhea, vomiting, and stomach pain.

Triamcinolone may cause certain side effects if used for a long time or in repeated doses.Steroids can affect the growth of children. If your child's growth isn't normal while taking hexatrione, tell your doctor.

Hexatrione can cause a variety of side effects.

  • Skin changes (acne or redness; bruising and discoloration);
  • Increased hair growth or thinning of hair
  • Nausea, bloating, and appetite changes;
  • Stomach or side pain
  • A runny or stuffy nasal passage;
  • Headache, sleep problems (insomnia);
  • A wound that heals slowly
  • Sweating a lot more than usual.
  • Changes in your menstrual cycle

There may be other side effects. For medical advice on side effects, call your doctor. Contacting the FDA in regards to side effects can be done via their toll free number at 1-800-FDA-1088.

Similar/related drugs

Cosentyx, Fazenda, Nplate, Promacta, Stelara, Taltz, and Simponi

Warnings

This medicine may not be available to you if your condition is idiopathic purpura or a fungus infection.

Before you take this drug

If you have an allergy to hexatrione, it is best not to use this drug.Hexatrione may not be available to you if your condition is a fungal infection or an idiopathic purpura.

Tell your doctor about any of the following:

  • Tuberculosis is an infection that can be active or chronic.
  • Idiopathic thrombocytopenic purpura (ITP);
  • Heart problems;
  • Herpes in the eye, glaucoma, or cataracts
  • A parasitic infection that can cause diarrhea (such as threadworms);
  • A disorder of the nerves and muscles, such as myasthenia gravis
  • A stomach ulcer; diverticulitis; and ulcerative colitis
  • A colostomy, ileostomy, or stomach operation
  • Low bone mineral density;
  • A thyroid or adrenal problem can be the cause.

Inform your physician if you are pregnant or nursing.

How to take Hexatrione?

Hexatrione can be given by a needle to various areas of the body, including a muscle or the area around a tendon or joint. It can also be injected directly into a skin lesion. This injection will be given by a healthcare provider.Hexatrione may not be used in the same way or for the same condition. Some brands can be given only once. Some brands may need to be taken regularly. Follow your doctor's instructions carefully.Hexatrione may suppress your immune system and make you more susceptible to infection. If you notice unusual bleeding or bruising, or if there are signs of infection, such as fever, weakness, cold or flu symptoms, skin lesions, diarrhea, or frequent or recurring illnesses, call your doctor.Eye damage can occur from long-term use. Your doctor may recommend regular eye examinations if you are receiving hexatrione for longer than six weeks.You may be instructed by your doctor to reduce salt intake when you are taking hexatrione. You may need to take a potassium supplement. Please follow all the instructions.Tell your doctor that you are using hexatrione. Inform any doctor that you see about hexatrione.Do not suddenly stop using hexatrione after repeated, long-term use. You may experience unpleasant withdrawal symptoms. You should ask your doctor about how to stop this medication safely.

What happens if I miss the dose?

If you are unable to attend an appointment, call your doctor and ask for instructions.Hexatrione can be taken in a single dosage. You will not have a regular dose schedule.

What happens if I overdose?

Overdoses are unlikely because hexatrione will be administered by a health professional in a medical environment.Hexatrione in excess is unlikely to cause any serious health problems. Long-term use of high doses may cause thinning of the skin, easy bruises, changes in body weight (especially on your neck, face, back, and waist), acne or facial hair growth, menstrual issues, impotence, or a loss of interest in sex.

What should be avoided?

Avoid overusing the joint after a triamcinolone injection. This includes high-impact sports or strenuous activities. You may cause joint damage.Avoid being around people who are sick. If you have been exposed to chickenpox or measles, call your doctor immediately for preventive treatment. Hexatrione users are at risk of serious or even fatal conditions.You should not take a live vaccine, such as a toxoid or "live" vaccine. This could cause a serious infection. Live vaccines include measles, mumps, rubella (MMR), polio, rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and the nasal flu (influenza) vaccine. Toxoid vaccinations include tetanus-tetanus-toxoid.

Interaction with other drug

It is sometimes not safe to take certain medications together. Some drugs may affect the blood levels of drugs that you are taking, causing side effects or making them less effective.

Inform your doctor of all the medications you are taking. Hexatrione can be affected by many drugs, including:

  • Antifungal or antibacterial medication
  • Hormonal replacement therapy or birth control pills
  • Blood thinners (Warfarin, Coumadin, and others);
  • A diuretic, or "water pill".
  • Oral medication, diabetes medicine, insulin
  • Medicine to treat tuberculosis
  • Nonsteroidal anti-inflammatory drugs (nsaids) include Advil, Aleve, and Celebrex.
  • Seizure medication.

The list of drugs that can interact with hexatrione is not exhaustive. This includes over-the-counter and prescription medicines, vitamins, and herbal products. This list does not include all possible drug interactions.