The Web Health


Gentamicin and prednisolone (ophthalmic)

Generic name: gentamicin and prednisolone (ophthalmic) [JEN-ta-MYE-sin-and-pred-NIS-oh-lone-off-THAL-mik]
Brand names: Pred-G, Pred-G S.O.P. ophthalmic, Pred-G S.O.P.
Ophthalmic suspension (0.3%–1%)
Drug class: ophthalmic steroids containing anti-infectives

What is Gentamicin and prednisolone ?

Gentamicin is a combination of antibiotic and steroid medicine used to treat inflammation in the eye caused by uveitis or other eye conditions. Gentamicin is prescribed when there is an increased risk of bacterial infections around or in the eye. This medication guide does not list all possible uses for prednisolone and gentamicin ophthalmic.

Side effects of Gentamicin and prednisolone

If you experience any of the following signs and symptoms of an allergic reaction: hives, difficulty breathing or swelling in your lips, face, tongue or throat. Seek medical assistance immediately. When gentamicin is applied to the eye, serious side effects are rare. However, they can occur if they are absorbed by the bloodstream.

Prednisolone and gentamicin can cause serious side effects. If you experience:

  • Eye swelling, redness, and discomfort (which may indicate infection)
  • Eye pain, tears, and sensitivity to lights
  • Tunnel vision and blurred vision are terms used to describe the phenomenon of seeing halos around light sources.
  • A wound that does not heal.

If you experience new or worsening pain in your eyes or swelling lasting more than 48 hours, stop using this medication and consult with your doctor.

Side effects of prednisolone and gentamicin include:

  • The eyes may be irritated by stinging or burning.
  • Blurred vision
  • Feeling like there is something in your eye
  • Unusual or unpleasant taste in your mouth

There may be other side effects. For medical advice on side effects, call your doctor. The FDA can be contacted at 1-800-FDA-1088 to report side effects.

Similar/related drugs

prednisone, diclofenac ophthalmic, ciprofloxacin for ophthalmic use, the ophthalmic form of azithromycin, dexamethasone ophthalmic, triamcinolone ophthalmic, and triamcinolone


If you have an infection in your eye (such as simplex herpes), then you should avoid using gentamicin or prednisolone.

Before you take this drug

This medicine should not be used if you're allergic to prednisolone or gentamicin or have a viral or fungal infection in your eye (including herpes). This medicine is not known to harm a baby in utero. Inform your doctor if you are pregnant. This medicine should not be used while breastfeeding. Administering this medication to those aged under 18 is not advised.

How to take Gentamicin and prednisolone ?

Read all instructions or guides that come with your medication and follow all directions. Follow the directions on the label. Before using eye medications, wash your hands. Before each use, shake the eye drops thoroughly. Applying eye drops requires just three simple steps - tilt back your head, pull down on your lower lid to form a pocket, hold the dropper above each eye, squeeze some drops out through a dropper into it - done! Close your eyes for a minute or two. Only use the prescribed number of drops. Use eye drops only when wearing soft lenses. Prednisolone and gentamicin contain a preservative that could permanently stain lenses. Use the medication at least 15 minutes prior to inserting your contacts.

Apply the ointment by pulling down your lower eyelid and tilting your head slightly back. In this pocket, squeeze a small ribbon of ointment out of the tube. Keep your eyes closed for a minute or two after you blink gently. Use a tissue to wipe off any excess ointment. Avoid touching the tip or placing it directly in your eye. If the tip is contaminated, it can cause serious vision problems. Store away from moisture or heat at room temperature. Store at room temperature, away from moisture and heat. When not in use, keep the tube or bottle tightly closed.

What happens if I miss the dose?

If you are almost due for your next dose, skip the missed dosage. Never take two doses of the same medicine at once.

What happens if I overdose?

Overdoses of prednisolone and gentamicin ophthalmology are not dangerous. If anyone accidentally swallows the medication, seek emergency medical attention. You can also call Poison Help at 1-800-222-1222.

What should be avoided?

Even if the other person has similar symptoms, do not share prednisolone and gentamicin. Avoid driving and doing any activity that requires clear vision. For a brief period, your vision may be blurred. You should only use eye drops prescribed by your doctor.

Interaction with other drug

Other drugs that you take are unlikely to affect the medicine used on your eyes. Many drugs interact with each other. Inform your healthcare provider about the medicines you take, including prescriptions and over-the-counter medicines, vitamins, and herbal products.