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Generic Name: Calfactant [Kal-FAK-tant]
Drug class: lung surfactants

What is Infasurf?

Infasurf, also known as "surfactant," is an agent that acts on the surface of the lungs. It supports normal lung function. This medicine works by mimicking the fluid that is naturally found in the lungs to maintain breathing.

Infasurf can be used to treat or even prevent respiratory distress syndrome in premature babies whose lungs are not yet fully developed.This medication guide does not list all possible uses of Infasurf.

Side effects of Infasurf

Infasurf has few side effects. It is possible that your baby may have breathing problems during this medication treatment. These problems could require additional treatment from health care professionals. You will be able to monitor your baby at all times during the treatment.

There may be other side effects. For medical advice on side effects, call your doctor. The FDA can be contacted at 1-800-FDA-1088 to report side effects.


This medication will be administered to your baby in the neonatal intensive-care unit (NICU) of a hospital or other similar setting.

Infasurf can be given directly to the baby through a breathing tube connected to a ventilator. A ventilator is a machine that helps your baby breathe better and get enough oxygen.During the treatment with Infasurf, your baby will be under constant supervision.

Similar/related drugs

Curosurf, poractant, beractant, calfactant, surfaxin, and lucinactant

Before you take this drug

Follow all instructions given by the carers of your baby to the letter.

Infasurf is given in a number of ways.

Infasurf can be administered directly to the baby's lungs via a breathing tube. This medication will be administered to your baby in the neonatal intensive-care unit (NICU) of a similar hospital.The breathing tube is attached to a ventilator, which helps your baby breathe more easily and get enough oxygen.

Infasurf should be given as soon after birth as possible, typically within 30 minutes.Infasurf can be given up to three times a day, every 12 hours.During treatment with Infasurf, your baby's vital signs, such as breathing, oxygen levels, and blood pressure, will be closely monitored.

What happens if I miss the dose?

Infasurf can be given by your healthcare provider as required. It is unlikely that your child will miss a dosage.

What happens if I overdose?

Infasurf will not cause an overdose if it is administered by a medical professional in a controlled setting. Overdoses of the calfactant are not expected to cause life-threatening symptoms.

What should be avoided?

After your baby is treated with Infasurf, follow your doctor's instructions regarding any restrictions on feeding, medication, or activity.

Interaction with other drug

The carers of your baby will monitor and manage all medication given to him or her during the NICU treatment. Infasurf is unlikely to cause drug interactions with other medications.

This includes vitamins, minerals, and herbal products. This includes minerals or herbal products.