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Gadobutrol

Generic Name: Gadobutrol GAD-oh BUE-trol Gadobutrol [GAD-oh BUE-trol]

Name of the brand: Gadavist
Dosage format: intravenous solution (604.72 mg/mL)
Classification of drugs: magnetic resonance imaging contrast media

What is Gadobutrol?

Gadobutrol is an agent for contrast that has magnetic properties. It is employed in conjunction with magnetic resonance imaging (MRI) or magnetic resonance imaging (MRA) to permit organs, blood vessels, and other non-bony tissue to be observed more clearly.Gadobutrol helps identify certain conditions of the spine and brain (central nervous system), the kidneys' blood vessels, and the heart. Gadobutrol may also be used to aid in the MRI of breasts for the detection of tumors in the breast.Gadobutrol can also be employed for other purposes that are not covered in this medication guide.

Side effects of Gadobutrol

Contact a medical professional immediately. If you are experiencing warning signs of a reaction, such as symptoms of hives, difficulty breathing, or swelling of your lips, face, and tongue,Certain side effects of gadobutrol could occur for several days after the injection.Gadobutrol could cause a fatal disease in those suffering from chronic kidney diseases. Contact your physician right now if you notice any of the symptoms that indicate this condition, like:

  • Burning, itching, swelling, as well as scaling or the skin's hardening;
  • Muscles weak;
  • Joint stiffness that affects your hands, arms, or legs;
  • Deep bone pain in your ribs or hips;
  • Difficulty getting moving;
  • Skin discoloration or redness.

Contact your doctor at anytime if you suffer from:

  • kidney issues: no or little urination; painless or difficult urine; swelling of your ankles and feet; being exhausted or lacking breath.

Common adverse effects of gadobutrol could be:

  • Headache;
  • Nausea;

This list does not constitute a comprehensive listing of potential side effects; other complications could also arise. Please consult your physician if any adverse reactions develop, and report any concerns to the FDA at 1-800-FDA-1088.

Similar/related drugs

Lexiscan, Glucagon, Mannitol, Arginine, Ceretec, Magnevist, and Gadavist

Cautions

Gadobutrol can trigger a life-threatening illness in patients suffering from severe kidney diseases. Your doctor will examine your kidney function prior to giving you gadobutrol.Gadobutrol is a substance that can remain inside your body for a number of months or even years after receiving the medication. It's unclear if this can cause health issues in those who have normal kidneys. Discuss with your physician if you have had several scans with an agent that contrasts, and also provide the date of the last scan.

Prior to using this drug

Gadobutrol could trigger a life-threatening illness in patients suffering from an advanced form of kidney disease. Your doctor will examine your kidney function prior to deciding whether you should take this medication.Gadobutrol may remain inside your body for months or even years after receiving this drug. It's not clear if this can cause health issues in those who have normal kidneys. Inform your physician if you have had multiple scans using contrast agents, and also provide the date of the last scan.Gadobutrol should not be taken if you have an allergy to it.

Inform your doctor if you were ever diagnosed with:

  • Renal disease (or if you're on dialysis);
  • Any reaction that is triggered by the contrast agent
  • Diabetes;
  • Hypertension;
  • Liver disease;
  • Asthma, asthma, fever, and food or drug allergies
  • An injury, surgery, or severe infection;
  • If you're over the age of 60,

Uncertainty exists as to whether this medication will harm an unborn baby.. Consult your physician if you are expecting.Breastfeeding while taking this medication is not advised.. Consult your physician about any potential risks.

How do I take Gadobutrol?

Gadobutrol is administered as an infusion to the vein. Your healthcare provider will offer you the injection.Inform your doctor that you are experiencing any burning, pain, or swelling of the needle during the time the medication is administered.Your physician or another health professional may decide to observe you for a brief period following the conclusion of your test. This is to ensure you do not suffer adverse reactions or side effects.

Info on dosage

Usual adult dosing regimen for CNS Magnetic Resonance Imaging:

0.1 milliliters/kg body weight (0.1 mg/kg) IV Bolus injection
Comments: administer via a power injector or manually with a flow rate of about 2 mL/sec. Check the manufacturer's product details for the amount that needs to be administered.
Use: Designed for use in conjunction with MRI to identify and assess areas of a dysfunctional BBB and/or a lack of circulation of the central nervous system.

Usual Adult Dose for Diagnostics:

0.1 milliliters/kg body weight (0.1 mg/kg) IV Bolus injection
Comments: Apply the medication via a power injector or manually at a rate of about 2 mL/second. Check the manufacturer's product details for the amount that needs to be administered.
Use: Recommended for use along with an MRI to determine the extent and presence of breast cancer that is malignant.

Usual Pediatric Dose for CNS Magnetic Resonance Imaging:

0.1 milliliters/kg body weight (0.1 mg/kg) IV Bolus injection
Comments: Apply the medication via a power injector or manually with a flow rate of about 2 mL/second. Consult the product specifications of the manufacturer for the amount required to be administered.
Use:
treatment for MRI to visualize and detect areas that have a damaged blood-brain barrier (BBB) or an abnormal flow of blood to the central nervous system.

What happens if I miss the dose?

Because gadobutrol is only used for the course of your MRI or MRA, it is not possible to follow a schedule of dosing.

What happens if I overdose?

Because gadobutrol is administered by a health expert in a medical environment, it is not likely for an overdose to occur.

Avoid this

Follow the instructions of your physician regarding any dietary restrictions on drinks, food, or any activity.

Interaction with other drug

Other drugs can interact with gadobutrol, such as medications that are prescribed and available over the counter, vitamins, and herbal products. Discuss with your doctor all your medications currently in use as well as any medications you are about to start or stop taking.