What is Fibrinogen?
Fibrinogen, a synthetic form of the protein found in the human body that helps blood clot, is made by humans. Fibrinogen can be used to treat bleeding in people who have a congenital deficiency of fibrinogen. This medication guide does not list all possible uses of fibrinogen.
Side effects of Fibrinogen
If you experience any of the following symptoms: hives, rash, tightness in your chest, wheezing, difficulty breathing, feeling as if you may pass out, or swelling of your lips, face, tongue, or throat,
Fibrinogen may cause serious side effects. If you experience:
- Signs of a Stroke: sudden numbness, weakness, or a severe headache; slurred or shaky speech; problems with vision, balance, or coordination.
- Signs of a blood clot in the lungs: chest pain, sudden hack, wheezing, and rapid breathing;
- Signs of a blood clot in the leg: pain, swelling, warmth, or redness on one or both legs.
- Heart attack symptoms: chest pain or pressure spreading to your jaw and shoulders, nausea, or sweating.
Some of the common side effects associated with fibrinogen include:
- Fever;
There may be other side effects. Need advice regarding side effects? Speak to your physician. The FDA can be contacted at 1-800-FDA-1088 to report side effects.
Similar/related drugs
Fibryga
Warnings
If you are allergic or have had an allergic reaction in the past, you should avoid using fibrinogen.
Before you take this drug
If you are allergic or have had an allergic reaction in the past, you should avoid using fibrinogen.
Tell your doctor about any of the following to ensure that fibrinogen will not harm you:
- A history of strokes or blood clots.
The effects of fibrinogen on an unborn child are unknown. Inform your doctor if you are pregnant or planning to become pregnant. There is no way to know if fibrinogen can pass into breastmilk or harm a baby who is nursing. You should tell your doctor if you're breastfeeding a child. Fibrinogen (a component of blood) is made using human plasma, which can contain viruses and infectious agents. Plasma donated is treated and tested to reduce the possibility of it being infected, but it is still possible that it can transmit diseases.Speak with your physician regarding any risks or advantages to taking this medicine.
How to take Fibrinogen?
You will be tested by your doctor to ensure that you are not suffering from any conditions that would make it unsafe for you to use fibrinogen. Do not alter the instructions on your prescription. Use this medication only as directed. Do not exceed the recommended dosage or use it for longer. A vein is injected with fibrinogen through an IV. It is possible that you will be taught how to use the IV at home. You should not administer this medication to yourself if you don't know how to inject the medicine and dispose of needles and IV tubing. Fibrinogen, a powdered medicine, must be mixed in a liquid before use. You should know how to mix and store your injections if you use them at home. Do not give fibrinogen or any other medicine through the same IV. Fibrinogen contains no preservative. You must use the vial immediately after piercing the rubber cap with a needle. Shaking the bottle can ruin the medicine. Only prepare your dose when you're ready to inject. The mixture should either be clear or lightly colored. If the color or appearance of your medication has altered or it contains particles, do not take. For new medication, call your pharmacist.
If you store it at room temperature, mixed medicine must be taken within 24 hours. This medicine comes in a single-use bottle (vial). Even if some medicine is left after injection, throw it away after use. Use a single disposable needle. Use syringes and needles only once. Ask your pharmacist how to dispose of sharps in a container that is puncture-proof. This container should be kept out of reach from both pets and children, to avoid contamination by either. Inform your doctor of any weight changes. Weight is a factor in determining the dosage of fibrinogen. Any changes to weight may have an impact on this. Your doctor may need to perform frequent tests to determine the length of treatment you will receive with fibrinogen. The powder should be stored in the refrigerator or in a cool, dark place. Do not freeze it, and keep it away from light. After the expiration dates have passed, throw away any vials that are still unused.
Details on dosage
Usual Adult Dose for Congenital Fibrinogen Deficiency:
When fibrinogen levels are unknown, dosing is recommended.
Dose (mg/kg) = [Target Level (mg/dL), Measured Level (mg/dL),]/1.7 (mg/dL for every mg/kg of body weight).
When fibrinogen levels are unknown, dosing is recommended.
Dose = 70 mg/kg of body weight
The maximum injection rate is 5 mL/min.
What happens if I miss the dose?
As soon as you remember a missed dose, take it immediately. If your next scheduled dosage is coming due, skip any missed dosage as taking additional medicine to make up for an unscheduled one is never advised.
What happens if I overdose?
Call 1-800-222-1222 for poison help or seek immediate medical attention.
What should be avoided?
If your doctor prescribes restrictions regarding food, beverages or activities for you to partake in, be sure to follow his/her orders accordingly.
Interaction with other drug
Other drugs, such as vitamins and herbal remedies, may also interact with fibrinogen. Inform all healthcare providers of any medications you are currently taking or intend to take in order to stay safe and healthy.
