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Fenoldopam

Name of the generic: fenoldopam [fen-OL’doe-pam”
Brand name: Corlopam.
Dosage format: intravenous solution (10 mg/mL)
Classification of drugs: agents for hypertensive emergency situations

What is Fenoldopam?

Fenoldopam can be used to rapidly reduce blood pressure for a brief period of time. Fenoldopam is typically prescribed in emergency situations in order to ensure that you are treated with other medications to lower your blood pressure. Fenoldopam can also be employed for other purposes that are not covered in this guideline for medication.

Side effects of Fenoldopam

See a doctor immediately. If you are experiencing symptoms that are warning signs of an allergic response, such as difficulty breathing, hives, and swelling of your lips, face, and tongue,

Fenoldopam can cause rapid heartbeats or a lightheaded feeling (like you could be stricken).

After treatment, contact your doctor immediately. If you suffer from:

  • Vision changes vision changes; headaches that are severe;
  • Weight gain, swelling;
  • Breathlessness;
  • Your neck is pounding or in your ears;
  • Low potassium level: leg cramps, constipation irregular heartbeats the chest flutters with more frequent urination or thirst. Numbness or tingling muscles becoming weak or a limp sensation

Common adverse effects of fenoldopam could be:

  • Feeling lightheaded;
  • Headache;
  • Nausea; or
  • Flushing (sudden heat, redness, or tingly sensation).

This isn't an exhaustive list of possible side effects, and others could happen. Consult your physician for advice regarding medical effects. You may report any adverse reactions to the FDA at 1-800-FDA-1088.

Similar or related drugs

Hydralazine, Enalapril, Labetalol, Apresoline, Dopamethyl, and Vasotec

Warnings

In the event of an emergency, you might not be able to tell doctors about your medical conditions. Be sure that any physician caring for you following the incident knows that you took fenoldopam.

Before you take this drug

If it is possible prior to receiving fenoldopam, inform your caregivers that you've had:

  • Glaucoma;
  • Low levels of potassium are present in the blood. Or
  • Asthma or sulfur allergies.

It isn't known if it will harm an unborn baby. But the presence of excessive blood pressure during pregnancy could lead to complications, such as the condition known as diabetes and eclampsia (dangerously high hypertension that could cause medical issues in both the mother and baby). The advantages of treating hypertension can outweigh the risks for the baby. You shouldn't breastfeed while you take fenoldopam.

In an emergency situation, you might not be able to inform caregivers whether you're breastfeeding or pregnant. Be sure that any doctor who cares for your baby or your pregnant mother is aware that you have received this medication.

How to take Fenoldopam?

Fenoldopam is administered as an injection into the vein. The healthcare professional will give the injection. Fenoldopam is typically administered only up to the point that your blood pressure returns to normal.

After your blood pressure is stable, you might receive other medications to prevent the pressure in your blood from becoming excessively high. Continue to take your blood pressure medication as prescribed, even if you are feeling good. High blood pressure is often not accompanied by signs. It is possible that you will need blood pressure medications throughout your life. When you're being treated with fenoldopam, your blood pressure might need to be monitored frequently. Follow your doctor's advice on how to prevent your pressure from becoming too high.

Details on dosage

Usual Adult Dose for Hypertensive Emergency:

0.01 to 0.3 mg/kg/min IV in an ongoing infusion. It may rise from 0.05 to 0.1 mg/kg/min every 15 minutes or until your blood pressure reaches the target.

Maximum dose: 1.6 mcg/kg/min

Time of treatment: Maintenance infusions can be used throughout the duration of up to 48 hours.

Comments:
Doses that are less than 0.1 mg/kg/min and a slow increase in the dose have been linked to lower reflex tachycardia.
The oral antihypertensives are available at any time once the blood pressure is stable after the infusion of this medication.

Use: In hospitals, short-term treatment for severe hypertension is indicated when a rapid, quickly reverseable, and urgent reduction in blood pressure is indicated clinically, as well as for malignant hypertension that has an eroding function of the end organ.

Usual Pediatric Dose for Hypertensive Emergency:

less than 1 month (at minimum 2 kilograms or full term) to 12 years old:
0.2 mg/kg/min IV for an ongoing infusion. It may rise in doses of 0.3 to 0.5 mg/kg/min every 20–30 minutes until the maximum dose

Maximum dose: 0.8 mcg/kg/min
Therapy duration: Maintenance infusions can be maintained for up to four hours.

Discussion: In general, doses greater than 0.8 mg/kg/min did not cause further reductions in blood pressure (MAP); however, they did cause a worsening of the tachycardia.
Utilization: In hospitals, for a brief-term decrease in blood pressure.

What happens if I miss a dose?

Because fenoldopam is given in a continuous dose during an emergency situation, you're unlikely to skip a dose.

What happens if I overdose?

Because fenoldopam is administered by a medical expert in an environment that is medical, overdose is not likely to occur. Inform your healthcare provider that you are feeling lightheaded after the infusion of fenoldopam.

What should be avoided?

Follow the instructions of your physician regarding any limitations on foods, drinks, or activities.

Interaction with other drugs

Inform your doctor about any other medications you take, including:

  • Beta blockers: carvedilol, atenolol, labetalol, and metoprolol; propranolol; and nadolol, as well as sotalol.

This list isn't complete. Other medications could interfere with fenoldopam, such as prescription and over-the-counter medicines, vitamins, and herbal products. There are many possible interactions between drugs. are listed here.