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Generic name: hydralazine [hye-DRAL-a-zeen]
Drug class: vasodilators

What is Apresoline?

It is a vasodilator. It helps relax the muscles within your blood vessels to aid in their dilation (widening). This lowers blood pressure and allows blood to flow more freely through your arteries and veins.Apresoline is a medication used in the treatment of hypertension. Apresoline can also be employed for other purposes that are not covered in this guideline for medication.

Side effects of Apresoline

See a doctor immediately. Get medical attention immediately if you notice symptoms or warning signs of an allergic response, such as difficulty breathing, hives, or swelling of your lips, face, tongue, throat, or face.

Apresoline may cause serious side effects. Contact your physician immediately in the following situations:

  • Chest tension or pain radiating into your shoulder or jaw;
  • Heartbeats that are fast or rapid
  • Feeling lightheaded; as though they have passed out;
  • Numbness, tingling, as well as burning or numbness in your feet or hands;
  • Uncomfortable or difficult to urinate;
  • Few or no urinations
  • Lupus-like syndrome: joint pain or swelling accompanied by fever glands that are swollen muscles, as well as chest pain, vomiting, odd thoughts or behaviours, and skin patches.

Common adverse effects of apresoline can be:

  • Chest pains, fast heart rate;
  • Headache
  • Nausea, vomiting, diarrhoea, and loss of appetite.

This is not a comprehensive list of all side effects. Other effects may also be present. Contact your doctor for advice regarding medical adverse effects. You can report any side effects to the FDA at 1-800-FDA-1088.


You shouldn't make use of Apresoline when you suffer from coronary arterial disease or rheumatic heart disease that affects the mitral valve.

Before you take this drug

It is not recommended to take Apresoline. If you have an allergy to the substance or suffer from:

  • Coronary artery disease;
  • Rheumatic cardiac disease, which affects the mitral valve

To ensure that apresoline is safe for you, inform your doctor if you ever experience:

  • Kidney disease;
  • Systemic lupus erythematosus;
  • Angina (chest pain);
  • A stroke.

It is unclear if this medicine could cause harm to a baby who is not yet born. Consult your physician if you are expecting or planning to be pregnant.Hydralazine is found in breast milk; however, the consequences for nursing infants aren't known. Inform your doctor if you are breastfeeding.Apresoline is not a prescription drug for use by anyone less than 18 years old.

How to take Apresoline?

Follow the directions on the prescription label. Don't take Apresoline in smaller or larger quantities or for longer than the recommended time.Your blood pressure needs to be regularly checked. It is also possible that you will require frequent blood tests.Continue to take this medicine according to the directions, even if you are not feeling well. A high blood pressure can have no signs. You could need medication for blood pressure throughout your life.Maintain an environment in which it remains at room temperature, free from moisture or excess heat.

What happens if I miss the dose?

Do the dose you missed as soon as you can remember. Avoid your missed dosage if you are close to the time of your next dose. Do not take extra medication in an attempt to make up for a dose you missed.

What happens if I overdose?

Get medical attention in an emergency or contact the Poison Help Line toll-free at 1-800-222-1222.Overdose symptoms can include agitated heartbeats, warmth, or tingling beneath your skin. It can also cause chest pain as well as feeling faint.

What should be avoided?

Be careful not to get up too quickly from a lying or sitting posture, as you might get dizzy. Make sure to get up slowly and steadily to avoid falling.

Interaction with other drug

Discuss with your physician your current medications and any new medications you begin or stop taking, in particular:

  • Diazoxide (an injectable blood pressure medication);
  • An mao inhibitor—isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

This list is not comprehensive. Other medications can interact with hydralazine. This includes medications that are prescribed and available over the counter, vitamins, and herbal products. The interactions of all potential drugs are included in this guideline for medication.




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