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Endocet 10/325

Generic name: acetaminophen and oxycodone [a-SEET-a-MIN-oh-fen-and-OX-i-KOE-done]
Names of brands: Endocet 10/325, Endocet 2.5/325, Endocet 5/325, Endocet 7.5/325, Nalocet,… list the 8 brands.
Drug class: narcotic analgesic combinations

What is Endocet 10/325?

Endocet 10/325 is an amalgamation of drugs that is used to treat mild to extreme pain.Endocet 10/325 is an opioid medication and could become habit-forming.Endocet 10/325 could be used for other purposes not covered in this medication guide.

Side effects of Endocet 10/325

Seek medical attention immediately. If you are experiencing warning signs of an allergic reaction, such as face, symptoms, hives,ives, breathing difficulties, or swelling of your lips, face and throat,Opioid medicines may slow or stop your breathing, and even death could occur. Anyone who cares for you must administer Naloxone Breathing, or seek medical attention if you experience prolonged breathing, pauses in your breathing or blue lips, or if you find it difficult to get back up.In some cases, acetaminophen could cause a serious skin reaction, which can cause death.This could occur even if you've used acetaminophen in the past but did not experience any reaction. Stop using Endocet 10/325 and consult your physician immediately in the event of a rash or redness on your skin that has spread and led to blisters or peeling.

Endocet 10/325 may cause serious side effects. Consult your physician right away if you experience:

  • Sighing, noisy breathing, deep breathing breath that stops;
  • An euphoric feeling, similar to you're passing out;
  • Fatigue, weakness, fever, bleeding, or swelling that is unusual;
  • The mind, or unusual thoughts or behaviors;
  • Issues with urination;
  • Liver issues liver problems, nausea nausea, stomach pain in the upper part of the stomach, fatigue, and lack of appetite dark urine, stools that are clay-colored, and jaundice (yellowing of the eyes or skin);
  • Low levels of cortisol—vomiting,  nausea, vomiting, lack of appetite, dizziness, a worsening tiredness or weakness;
  • Serotonin levels that are elevated in the body include anxiety, hallucinations, fever, sweating, shaking, a fast heart rate, and muscle stiffness. Inability to control nausea, vomiting, and diarrhea

Breathing problems that are serious can be more common in older adults and those who are weak or suffer from the syndrome of wasting as well as chronic respiratory problems.

Common adverse reactions include:

  • Nausea, tiredness, fatigue, and dizziness;
  • Extreme joy or sadness
  • Nausea, vomiting, and stomach pain;
  • Constipation

This isn't a complete list of all the side effects. Other side effects could occur. Consult your physician to seek medical advice on adverse effects. You can report symptoms to the FDA at 1-800-FDA-1088.

Similar/related drugs

aspirin, acetaminophen, tramadol, duloxetine, naproxen, oxycodone, and tylenol


The misuse of opioids could lead to addiction, overdose, or even death. Keep the medication in a location where other people are unable to access it.Opioid medicine taken during pregnancy could trigger withdrawal symptoms that could be life-threatening for the baby.Side effects that are fatal can be experienced if you take opioid medication in combination with alcohol or other medications that can cause drowsiness or a slowing of breathing.Take a break from this medication and contact your doctor immediately if you notice the appearance of a rash or redness on your skin that gets worse and leads to peeling and blisters.

Before you take this drug

It is not recommended to take Endocet 10/325. if you're sensitive to acetaminophen or oxycodone or are:

  • Serious, severe asthma or breathing issues severe asthma or breathing problems.
  • A blockage in your stomach or your intestines

Inform your doctor if you were ever diagnosed with:

  • Breathing issues, sleep apnea;
  • The liver condition;
  • Addiction to alcohol or drugs;
  • Kidney disease;
  • A head injury or seizures;
  • Problems with urination and
  • Troubles that concern your pancreas, thyroid, or gallbladder.

If you are taking opioid medication while pregnant, your baby may develop a dependence on the medication. This can cause withdrawal symptoms that can be life-threatening for the infant after it is born. Babies born dependent on opioids may need medical treatment for several weeks.

Consult a physician before using opioids if you are nursing. Tell your doctor when you experience severe sleepiness or slow breathing during the breastfeeding period.

How to take Endocet 10/325?

Follow all the instructions on the prescription label. Do not take this medication in larger quantities or for longer than the time prescribed. An overdose can damage your liver or cause death. Inform your doctor if you notice an increase in your desire to take more of this medication.Do not share your opioid medication with a person, particularly one who has an addiction history. A misuse of the medicine can result in addiction, overdose, or death. Place the medicine at a distance from where others can't access it. Giving away or selling opioids is against the law.Make sure to measure the liquid medicine with care. Make use of the dosing syringe supplied or use a dosage-monitoring device (not an ordinary spoon).If you require an operation or other medical examinations, inform your doctor prior to the time that you're taking this medication.Do not stop taking this medicine abruptly. Follow the instructions of your physician about the process of tapering your dose.Place it in a cool, dry place far from heat and moisture. Make a note of your medication. It is important to be aware if someone is taking it incorrectly or without a prescription.Don't keep any of the leftover medication for opioids. A single dose can cause death if someone is using this medication improperly or in a certain way. Ask your pharmacist where you can find a drug disposal program. If there's no taking-back system, then flush any unneeded medicine into the toilet.

What happens if I miss the dose?

Because Endocet 10/325 is prescribed for pain, you're less likely to skip a dose. Do not miss any doses in the event that it's almost time for the next dose. Don't take two doses at once.

What happens if I overdose?

Get medical attention immediately, contact emergency medical attention, or call the Poison Help Line at 1-800-222-1222. A dose that is too high for this medicine could be fatal, particularly for children or any other user of the medicine without a prescription. Overdose symptoms may include vomiting, nausea, sweating, severe dizziness, narrow pupils, and slow breathing. It could also mean an inability to breathe.A doctor may suggest getting Naloxone (a medication to treat an overdose of opioids) and carrying it around always. Someone who cares for you could administer Naloxone if you cease breathing or aren't awake. Your caregiver needs to get medical attention in an emergency and could be required to perform CPR (cardiopulmonary resuscitation) on you as they wait for assistance to arrive.You can purchase naloxone at pharmacies or your local health department. Be sure that anyone who cares for you is aware of where you store naloxone and how to utilize it.

What should be avoided?

Avoid operating machinery or driving until you are aware of the way Endocet 10/325 affects your health. Drowsiness or dizziness can lead to accidents, falls, or even severe injuries.Avoid drinking alcohol. Dangerous side effects or death may occur.Talk to your doctor or pharmacist prior to using any other medication that could contain acetaminophen (sometimes known as APAP). Combining certain medicines could cause a deadly overdose.

Interaction with other drug

There is a possibility of breathing issues or withdrawal symptoms when you begin or stop taking certain medications. Talk to your doctor if you are also taking any antibiotic or antifungal medication. blood pressure or heart medicine, medication for seizures, or medication for treating HIV, as well as Hepatitis C.Opioid medicine may interact with other drugs, causing deadly side effects or even death. Be sure your doctor is aware if you are taking:

  • Cold or allergy medications such as the bronchodilator asthma or COPD medication or diuretic ("water pill");
  • Medications to treat motion sickness and irritable bowel syndrome medications for motion sickness, irritable bowel syndrome, or an overactive bladder;
  • Other opioids, such as pain medication as well as the prescription cough medicine;
  • A sedative such as Valium, diazepam, alprazolam, lorazepam, Xanax, Klonopin, Versed, and more
  • Medications that induce sleep or reduce your breathing rate—a sleep pill or muscle relaxer, a medicine to treat mental illness
  • Serotonin-related drugs can alter the levels within your body, such as a stimulant or medication used to treat depressive symptoms, Parkinson's disease, migraine headaches, severe infections, vomiting, and nausea.

This list isn't complete. Other medications could be affecting Endocet 10/325, which includes medications that are prescribed and available over the counter, vitamins, and herbal products. The interactions of all drugs are included in this list.



Prescription only

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NDC 60951-712-70, Endocet, 10 mg / 325 mg, side 1 is E 712,