The Web Health



Name of the generic: dexlansoprazole [DEX-lan SOE-pra-zol] [DEX-lan-SOE-pra-zol]
The brand names are Dexilant and Kapidex.
Dosage format: oral delayed-release capsule (30 mg; 60 mg)
Drug class: proton pump inhibitors

What is Dexlansoprazole?

Dexlansoprazole helps treat stomach acidity that is caused by stomach reflux disease (GERD) and also erosive esophagitis (damage of the esophagus due to stomach acids).

Dexlansoprazole can also be used for reasons not mentioned in this medication guide.

Side effects of Dexlansoprazole

Contact a medical professional immediately. If you are experiencing symptoms that indicate an allergy, such as symptoms of hives, breathing difficulties, or swelling of your lips, face, and tongue,

Dexlansoprazole can cause serious adverse side effects. Contact your doctor immediately if you suffer from:

  • Extreme stomach pains; diarrhea that is bloody or watery
  • A seizure (convulsions);
  • Suddenly experiencing pain or difficulty moving your wrist, hip, or back
  • Kidney issues: symptoms of kidney problems include fever, rash, nausea, lack of appetite, joint pain, not urinating as often as usual, increased weight, and bloody urine.
  • Low magnesium—dizziness, fast or irregular heart rate, tremors (shaking) or jerking muscle movements, feeling jittery, muscle cramps, muscle spasms in your hands and feet, coughing or choking feeling;
  • The symptoms are either getting worse or new for lupus—joint pain, as well as an itch on your arms or cheeks that gets worse in the sun.

Long-term use of dexlansoprazole can cause stomach-related growths known as fundic polyps. Consult your doctor about the possibility.

If you take dexlansoprazole for more than three years, you could be developing a vitamin B-12 deficiency. Consult your doctor on how to deal with this issue when you get it.

Common adverse reactions to dexlansoprazole include:

  • Nausea, vomiting, stomach pain, gas;
  • Diarrhea;
  • Headache;
  • Throat discomfort, sore throat, mouth pain, sore throat
  • Nasal congestion and sinus pain, sinus pain, or any other symptoms of a cold.

This isn't an exhaustive list of all the side effects. Other side effects could occur. Consult your physician to seek medical advice on the effects. You can report any side effects to the FDA at 1-800-FDA-1088.


Dexlansoprazole could cause kidney problems. Inform your doctor that you're having fewer urinations than normal or if there is some bloody urine.Diarrhea could be a sign of a newly developed disease. Contact your physician. If you experience diarrhea that's watery or contains diarrhea

Dexlansoprazole can trigger new or worsening symptoms of lupus. Consult your physician if you are experiencing joint pain and an itch on your arms or cheeks that gets worse when exposed to sunlight.It is possible that you are more likely to suffer broken bones when you take dexlansoprazole for a long time or more than once daily.

Before you Take this Drug

Heartburn is a common sign of a coronary attack. Seek medical attention immediately when you experience chest pain that is spreading into your shoulder or jaw and when you experience anxiety or feeling lightheaded.It is not recommended to use this medication if you are allergic to dexlansoprazole or if you suffer from:

  • You experienced breathing issues, kidney issues, or a severe allergic reaction following taking this medication in the past.
  • Also, you can take a drug that also contains rilpivirine (complera, edurant, or odefsey).

Speak to your doctor if you have ever suffered from:

  • Serious chronic liver illness;
  • Osteoporosis;
  • Low bone mineral density (osteopenia)
  • Low levels of magnesium are present in your blood.

It is possible that you are more likely to sustain fractured bones in your wrist, hip, or back when you are taking a long-term proton pump inhibitor or more than once daily. Talk with your doctor about ways to ensure your bones are healthy.

Dexlansoprazole could cause harm to a baby who is not yet born. Use effective birth control to stop pregnancy and notify your physician if you are pregnant.

It is not recommended to breastfeed while taking this medication. Consult your physician about any potential risks.Dexlansoprazole has not been permitted for use by anyone younger than 12 years old.

How to Take Dexlansoprazole?

Follow the instructions on the prescription label and also read all medication guides or instruction sheets. Follow the medication exactly as prescribed.Take dexlansoprazole by drinking a full cup of fluid.Dexlansoprazole is a drug that can be taken with or without meals.Suck the capsule whole, and don't crush or chew on it, break it, or break it open.

If you are unable to swallow a capsule in its entirety, crack it and mix the medication into an applesauce spoonful. Take the medicine immediately without chewing. Don't save the mixture to use later.

To treat erosive esophagitis and reduce heartburn, dexlansoprazole can be prescribed for up to 6 months for adults and for between 4 and 16 weeks in children ages 12–17. Follow the doctor's instructions for dosing extremely carefully.Make sure to take this medicine for the prescribed amount of time, even if symptoms improve quickly.

Consult your doctor if symptoms do not improve or if they get worse when you take dexlansoprazole.This medication can alter the results of certain tests. Be sure to inform any doctor treating you that you're taking dexlansoprazole.

Dexlansoprazole could also alter the urine test used to screen for drugs and cause inaccurate results. Inform the lab staff that you are taking dexlansoprazole.Place it in a cool, dry place far from heat and moisture.

Details on Dosage

Usual Adult Dose for Erosive Esophagitis:

Treatment of Erosive Esophagitis (EE): 60 mg orally daily
The length of treatment can be up to 8 weeks
Dosage for maintenance 30 mg taken orally every day
The treatment duration can last up to 6 months.
Patients can receive maintenance doses to help relieve the symptoms of heartburn.
The controlled studies of treatment maintenance do not last beyond six months.
All grades of EE
Maintaining the healing EE
Relieves heartburn

Usual Adult Dose for Gastroesophageal Reflux Disease:

30 mg taken orally every day
Therapy duration: 4 weeks
Use: Treatment for heartburn caused by symptomatic, non-erosive GERD (GERD)

Usual Pediatric Dose for Erosive Esophagitis:

Ages 12 and over:
Emotional healing: 60 mg once orally every day
Therapy duration: up to 8 weeks
Dosage for maintenance 30 mg taken orally every day
The duration of treatment: up to 6 months
Patients can receive maintenance doses to help relieve the symptoms of heartburn.
Controlled studies of maintenance therapy showed that they did not last beyond 16 weeks.
All grades of EE
Maintaining the healing EE
Heartburn relief

Usual Pediatric Dose for Gastroesophageal Reflux Disease:

12 years old and over 30 mg taken orally twice every day
Therapy duration: 4 weeks
Treatment for heartburn that is symptomatic and non-erosive GERD

What Happens if I Miss the Dose?

Do not take the medicine for as long as you can. However, avoid any missed doses if it's nearing the time to take the next dose. Don't take two doses at a time.

What Happens If I Overdose?

Get medical attention in an emergency or contact the poison help line at 1-800-222-1222.

What Should be Avoided?

Dexlansoprazole may cause diarrhea. It could be an indication of an infection that has recently developed. If you experience diarrhea that is bloody or watery, contact your doctor. Don't take anti-diarrhoea medication unless you are advised to do so by your physician.

Interaction with Other Drugs

Inform your doctor about all the medications you take. Numerous drugs can interact with dexlansoprazole, specifically:

  • Methotrexate;
  • Rifampin;
  • St. John's wort
  • Warfarin (Coumadin, Jantoven).

This is not a complete list, and other medications may influence dexlansoprazole. This includes over-the-counter and prescription drugs, vitamins, and herbal products. The interactions of all drugs are included here.