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Generic name: azilsartan and chlorthalidone [AY-zil-SAR-tan-and-klor-THAL-i-done]
The class of drug: angiotensin II inhibitors containing thiazides

What is Edarbyclor?

Edarbyclor is a mixture consisting of azilsartan and chlorthalidone. Azilsartan is an angiotensin II receptor blocker (sometimes known as the ARB).Chlorthalidone can be described as a thiazide diuretic (water pill) that prevents your body from taking in too much salt. This could cause fluid retention.Edarbyclor helps treat the problem of high blood pressure (hypertension). A reduction in blood pressure can reduce the risk of having a stroke as well as a coronary heart attack.

Side effects of Edarbyclor

See a doctor immediately. If you show symptoms of an allergic reaction Edarbyclor: hives and breathing problems or swelling of your lips, face, and tongue.

Contact your doctor immediately for:

  • Feeling like you might pass out;
  • Minimal or no urination
  • Swelling and weight gain, or feeling tired swelling, weight gain, or feeling short of breath
  • Indications of an imbalance in electrolytes dry mouth, extreme thirst, weakness, drowsiness or a restless sensation, confusion, increased or reduced urination, vomiting and nausea, constipation and muscle pain, weakness, a fast heart rate, or seizures (convulsions)

Common Edarbyclor adverse effects could include:

  • Dizziness;
  • Feeling exhausted.

This list isn't an exhaustive compilation of possible side effects from Zoloft use. Other side effects could occur. Contact your physician for advice regarding medical effects. You may report any adverse reactions to the FDA at 1-800-FDA-1088.

Similar or related drugs

metoprolol, amlodipine, lisinopril, losartan, and furosemide hydrochlorothiazide


You shouldn't take Edarbyclor when you are not able to urinate.Don't use it when you are pregnant. Stop taking the medication and notify your doctor when you are pregnant. Consult your physician for a blood pressure medicine that is safe for use during pregnancy.If you are diabetic, do not take Edarbyclor along with any other medicine that contains Aliskiren (a blood pressure medication, e.g., Amturnide, Tekturna, Tekamlo, or Valturna).

Prior to use this drug

Do not take Edarbyclor in the event that you are sensitive to chlorthalidone or azilsartan or cannot urinate.If you are diabetic, take care not to make use of Edarbyclor along with any other medication that includes Aliskiren (a blood pressure medication).It is also possible to stay clear of taking Edarbyclor along with aliskiren in the event that you suffer from kidney problems.

To ensure that this medication is suitable for you, inform your physician if you suffer from:

  • Kidney or liver disease;
  • Gout;
  • An unbalanced electrolyte (such as the low level of potassium found in your blood);
  • Stroke, heart disease,
  • If you are dehydrated.

Don't use Edarbyclor when you are expecting. Stop taking the medicine and notify your doctor immediately if you find yourself pregnant.Azilsartan and chlorthalidone could cause harm or even death to the baby's unborn when you use the medication in your second or third trimester. But being high in blood pressure during pregnancy could result in complications like the condition known as eclampsia or diabetes (dangerously elevated blood pressure that could cause medical issues in both the mother and the baby). Talk to your doctor about a blood pressure medication that is safe to take during pregnancy.You shouldn't breastfeed when you take this medicine.Edarbyclor is not recommended to be used by anyone younger than 18 years of age.Edarbyclor pregnancy and breastfeeding warnings (more details)

Similar or related drugs

metoprolol, amlodipine, lisinopril, losartan, and furosemide hydrochlorothiazide

How to take Edarbyclor?

You should take Edarbyclor exactly as directed by your physician. Follow all instructions on your prescription label, and review all medication guides and instructions sheets. Your doctor may alter your dosage.You can take Edarbyclor in combination with or without food.Your blood pressure needs to be checked regularly. The kidneys may also require a check.There is a possibility that you may experience very high blood pressure during the time you are taking this medicine. Consult your physician if you are suffering from diarrhea or are sweating more than normal.Use this medication according to the directions, regardless of whether you feel good. The high blood pressure is often accompanied by no signs. It is possible that you will need medication for blood pressure throughout your life.Keep the container in its original place at room temperature and away from heat, moisture, and light.

Details on dosage

Usual Adult Dose for Hypertension:

The first dose is: Azilsartan 40 mg; chlorthalidone 12.5 mg, once orally every day.
Maximum dosage: Azilsartan 40 mg; chlorthalidone 25 mg, once orally every day.
Correction of any volume loss before administration, particularly for patients suffering from impairment in renal function or who are taking diuretics at high doses.
Increase the dose in the 2–4-week period if necessary to meet blood pressure goals.
Patients who are not controlled by azilsartan monotherapy at 80 mg may be able to achieve diastolic and systolic blood pressure reductions of 6 and 13 mmHg, respectively, after having switched to the first dose of the drug; patients who are not controlled by chlorthalidone 25 mg in monotherapy could have additional diastolic or systolic blood pressure reductions of 10 and 7 mmHg according to the dose that was initially prescribed for this drug.
This drug can be used at the beginning of treatment when multiple drugs are needed to meet blood pressure goals.

What happens if I miss the dose?

Do not take the medicine for as long as you are able, but do not take your missed dosage if it's close to the time of the next dose. Avoid taking two doses at the same time.

What happens if I overdose?

Get medical attention in an emergency or contact the poison help line at 1-800-222-1222.

What should be avoided?

Don't take salt substitutes or potassium supplements unless your physician has instructed you to.Be careful not to get up too quickly from a lying or seated position. You could be dizzy.

Interaction with other drugs

Inform your physician of any other medications you take, especially:

  • Digoxin;
  • Lithium;
  • Diuretic, also known as a "water pill";
  • Other blood pressure and heart medications for blood pressure or heart

This list isn't complete. Other medications can interact with azilsartan or chlorthalidone, such as prescription and over-the-counter medicine, vitamins, and herbal products. Some interactions with drugs are not listed here. are listed here.



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