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Generic Name: Pegfilgrastim (PEG-fil-GRASstim)
Brand names: Fulphila Fylnetra Neulasta Onpro Kit Nyvepria… Show all 8 brands.
Drug class: colony-stimulating factors

What is Fylnetra?

Fylnetra prevents neuopenia, a condition caused by chemotherapy. Fylnetra, a type of protein, stimulates white blood cell growth that helps your body fight infections. Fylnetra can be used in other ways not mentioned in this guide.

Side effects of Fylnetra

If you experience any of the following symptoms, seek emergency medical attention: hives; skin rash; sweating; warmth or tingly sensation; dizziness; rapid heartbeats; difficulty breathing; or swelling of your lips, face, tongue, or throat. Capillary Leak Syndrome is a rare but potentially serious side effect of pegfilgrastim therapy, so if any of the following symptoms arise while taking this drug it should be reported immediately to a physician:

Fylnetra can cause serious side effects. If you experience:

  • A sudden and severe pain that spreads from your upper left stomach to your shoulder
  • Are You Suffering from Sudden and Severe Chest, Abdomen or Back Pain
  • You may experience severe pain in any part of your body.
  • Fever, tiredness;
  • Rapid breathing;
  • Easy bruising, unusual bleeding, or purple or red patches under the skin
  • A hard lump or bruise where the injection was made
  • Kidney problems: little or no urine, dark urine or pink urine, swelling of the face or legs.

Should any adverse side effects arise during cancer treatment, its progression may be delayed or suspended altogether.

Fylnetra can cause the following side effects:

  • Bone pain
  • Are your arms or legs hurting? You could experience discomfort there.

Side effects may arise. For medical advice on any adverse reactions, speak to your healthcare provider immediately or call 1-800-FDA-1088; the FDA also can be reached directly for reports regarding side effects at 1-800-FDA-1088.

Similar/related drugs

Filgrastim, Neulasta, Zarxio, Pegfilgrastim, Neupogen, and Granix


Please read and follow all instructions printed on your medication label or package, as well as inform your healthcare provider of all medical conditions, allergies and medicines currently taken by yourself or family members.

Before you take this drug

Fylnetra should not be used if you have an allergy to Fylnetra, Filgrastim, or Neupogen.

Inform your physician of any of the following issues:

  • Sickle cell disorder;
  • Kidney disease
  • Acute myeloid leukemia
  • Radiation treatment
  • Myelodysplastic syndrome
  • A latex allergy.

You could develop a blood disease or cancer if you receive Fulphila or radiation, with or without chemotherapy, for breast cancer or lung carcinoma. You should ask your doctor about the risk. Inform your physician immediately if you become pregnant or nursing.

How to take Fylnetra?

Read all instructions or guides that come with your medication and follow all directions. Follow the instructions on your prescription label. Fylnetra shouldn't be taken within 24 hours or 14 days of receiving chemotherapy. Fylnetra should be administered through subcutaneous injection and will be provided to you with instructions by the healthcare provider to administer correctly. Please read and follow all directions included with your medication carefully, if there are any misunderstandings seek assistance from either your pharmacist or doctor immediately. If in any instance the instructions seem confusing please seek help from them or consult them prior to taking your medicine. Prepare your injection only when ready to administer it. If the medication appears cloudy or has changed color or contains particles, do not use it; contact your pharmacist if this occurs for new medicines. Your blood may need to be tested regularly. Do not use the prefilled syringe to measure the correct dose of Fylnetra for a child weighing less than 99 pounds. Your doctor may need to perform medical tests in order to determine the length of treatment you should receive with Fylnetra. Keep the prefilled syringe protected from light in its original packaging in the fridge. Do not shake or freeze. Before injecting the dose, remove the syringe from the refrigerator. Let it sit at room temperature for between 15 and 30 minutes. Thaw a frozen syringe in the refrigerator. Use only syringes that have not been frozen before. Use a syringe if it has been at room temperature for longer than 48 hours. Fylnetra syringes, Fulphila syringes, or Stimufend should not be used if they have been at room temperature for more than 72 hours. Use a Ziextenzo that has been at room temperature for longer than five days. The Neulasta Injector Onpro is a device that you place on your skin to deliver fylnetra at a certain time. Wear the device for at least 27 hours prior to the start of the dose. The dose will be released slowly from the device over a period of 45 minutes. Refrigerate Neulasta Onpro until you're ready to use it. Use an Onpro that has not been in the refrigerator for more than 12 hours. Use a prefilled Nyvepria syringe if it has been out of the fridge for more than 15 days.

You or your caregiver should check Neulasta Onpro to ensure it is functioning properly. Each Onpro injector or prefilled syringe is only for one-time use. After one use, throw it out, even if the medicine is still inside. Only use a needle or syringe once, and then store them in an "as sharps" container that is puncture-proof. Be sure to follow local or state laws on how to properly dispose of the container. Keep the container out of the reach of pets and children.

What happens if I miss the dose?

If you missed an injection or have any problems with your Neulasta Onpro device, call your doctor.

What happens if I overdose?

Call 1-800-222-1222 for poison help or seek immediate medical attention. Overdose symptoms can include pain in the bones, difficulty breathing, shortness of breath when lying down, foamy mucus from a cough, cold skin, anxiety, and rapid heartbeats.

What should be avoided?

While wearing Neulasta Onpro, avoid driving or operating machinery.

Interaction with other drug

Fylnetra may interact with other drugs, such as prescription and over-the-counter medicines, vitamins, and herbal products. Inform your doctor of all the medicines you are taking and those that you stop or start using.



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