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Docefrez

Brand names: Docefrez and Taxotere
Drug Class: Miotic Inhibitors

In the U.S., Docefrez has been stopped. There may be equivalents if generic versions have been approved by the FDA.

What is Docefrez?

Docefrez, a cancer medication, interferes with cancer cell growth and spread in the body. Docefrez can be used to treat lung cancer and prostate carcinoma. It is also effective in treating stomach cancer, head and neck cancer, and breast cancer. Docefrez can be used in other ways not mentioned in this guide.

Warnings

Docefrez may cause serious side effects, including death. This is especially true if the dose is high, you suffer from liver disease, or you've had platinum-containing chemotherapy in the past (cisplatin, carboplatin, or oxaliplatin). A life-threatening reaction to Docefrez is also possible. Seek emergency medical attention if your skin becomes swollen, you experience hives or a rash on the skin, you are having difficulty breathing, or you think you may pass out. Docefrez lowers blood cells, which help the body fight infection and clot your blood. You will have to test your blood often. These tests may delay your cancer treatment. Docefrez may cause fluid retention or serious adverse skin reactions. If you notice swelling in your feet or ankles, a rapid weight increase, or if your skin is red and peeling on your hands and feet, call your doctor.

Before you take this drug

Docefrez should not be given to you if your white blood cells (WBCs) are low or if there has been a severe reaction to polysorbate 80 or docetaxel.

Tell your doctor everything you know about your health and medications. Docefrez may cause serious side effects, including death.

  • If you are receiving high doses
  • If you have liver disease, it is important to consult your doctor.
  • If you have non-small-cell lung cancer and have previously been treated with platinum chemotherapy (cisplatin, carboplatin, or oxaliplatin), you may be able to receive a prescription for a new treatment.

Tell your doctor about any of the following to ensure that Docefrez will be safe for you:

  • Alcoholism or liver disease
  • Heart disease
  • Fluid retention;
  • Are You Wanting to Reduce Alcohol Intake

Docefrez may increase your risk for other cancers, including leukemia. Your healthcare provider can inform you more of how this medicine affects your risks. your risk. Docefrez can harm an unborn child. Use birth control during treatment with Docefrez to prevent pregnancy. After your treatment, follow your doctor's advice on how long you should continue to avoid pregnancy. Docetaxel is not known to pass into breast milk. It is also unknown if the drug could harm a baby who was nursing. Docefrez should not be taken while breastfeeding.

Similar/related drugs

Ibrance, Opdivo, Erleada, Retevmo, Keytruda, Rybrevant, and methotrexate

How to take Docefrez?

Docefrez injections are usually given through an IV once every three weeks. This injection will be given by a healthcare provider. Other cancer drugs may be given at the same time. If you experience any pain or swelling when the medicine is being injected, tell your caregivers. If you get Docetaxel on your skin, it can be dangerous. If this occurs, immediately wash with soap and warm water. Docefrez lowers blood cells, which help the body fight infections and clot blood. You will have to test your blood often. These tests may delay your cancer treatment. To prevent allergic reactions or serious side effects, you may be prescribed steroid medication. Use the steroid as prescribed by your doctor. If you experience any problems with your vision while taking Docefrez, it is important to get this checked.

What happens if I miss the dose?

If you miss your Docefrez appointment or miss a dose, call your doctor to get instructions.

What happens if I overdose?

Call 1-800-222-1222 for poison help or seek immediate medical attention.

What should be avoided?

Always remain alert while driving or performing other tasks requiring concentration. Stay away from people who are sick. If any signs indicate an infection, notify your physician right away. Prevent activities which could increase your risk of injury or bleeding by taking extra measures when shaving and brushing teeth - for instance taking extra measures when shaving could prevent shaving-induced bleeding! Docefrez is alcohol-based and can cause you to feel drunk when it's injected. On the day you receive your Docefrez, avoid drinking alcohol. This medicine may pass into bodily fluids (urine, feces, or vomit). Avoid letting your body fluids come into contact with surfaces or your hands for at least 48 hours after receiving a dose. While cleaning up body fluids from a patient, handling contaminated garbage or laundry, or changing diapers, caregivers should wear rubber gloves. Hands should be washed before and after gloves are removed. Separately, wash soiled linens and clothing.

Side effects of Docefrez

If you experience any of the following symptoms of an allergic reaction: hives or a red rash on your skin; difficulty breathing; feeling as if you could pass out; swelling in your face, lips, and throat, you may need to seek emergency medical attention.

If you experience:

  • Sudden vision problems;
  • Redness, swelling, heat, or changes in the skin where the injection has been given;
  • Extreme weakness, severe vomiting, or diarrhea;
  • Redness or peeling on the hands and feet
  • You may experience tingling, numbness, or burning in your feet or hands.
  • Signs and symptoms of infection: fever, swollen or bleeding gums, sores on the skin, difficulty swallowing, flu-like symptoms, a cough, breathing problems;
  • The feeling of being drunk: confusion, stumbling, and extreme drowsiness
  • Low blood cell counts; fever, chills, and fatigue; flu-like symptoms; mouth sores or skin sores easy bruising. Unusual bleeding. Pale skin. Cold hands and feet. Feeling light-headed.
  • Low blood red cells pale skin, feeling dizzy or light-headed, rapid heartbeat, difficulty concentrating
  • Low blood platelets—easy bruising and unusual bleeding in the nose, mouth, vagina, or rectum; purple or red pinpoints under your skin.
  • Fluid retention: little or no urination; swelling of the ankles and feet; rapid weight gain;
  • Liver problems include upper stomach discomfort, loss of appetite, and dark urine.

This medicine may have more side effects for older adults.

Common Docefrez side effects may include:

  • Feeling tired or weak?
  • Mouth sores and altered taste sensations
  • Swelling;
  • Nausea, vomiting, and loss of appetite
  • Constipation, diarrhea;
  • Hair loss can be permanent.
  • Muscle or joint pain
  • Rash;
  • Changes to the fingernail and/or toenail

There may be other side effects. For medical advice on side effects, call your doctor. The FDA can be contacted at 1-800-FDA-1088 to report side effects.

Interaction with other drug

Docefrez contains alcohol. Other drugs that make you sleepy may worsen your feeling of drunkenness. Before taking sleeping pills, opioid pain medication, muscle relaxers, anxiety, depression, or seizure medicine, consult your doctor. Docetaxel may interact with other drugs, such as prescription and over-the-counter medicines, herbal products, vitamins, and supplements. Inform your doctor of all the medicines you are currently taking and those that you will begin or stop using.