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Deplin

Generic name: l-methylfolate [L-METH-il-FOE-late]
Brand names: Denovo Deplin Elfolate Forte XaQuil XR L-Methylfolate
Drug class: vitamins

What is Deplin?

The B-vitamin folate is found in many natural foods. Folic acid, a synthetic form of folate added to vitamin and mineral supplements or processed foods, is a man-made version. The human body needs folate to produce red blood cells. Folate deficiency can be caused either by disease, medication, or not eating enough folate. Folate deficiency may cause anemia, which is a decrease in red blood cells. Folate deficiency can also cause high levels of a certain amino acid in the blood, a condition called hyperhomocysteinemia (HYE-per-HOE-moe-sis-tin-EE-mee-a). Deplin is an approved medical food that can be used by people with folate deficiencies. The medicine can also be used by people who suffer from major depressive disorder and have a folate shortage, or by people who suffer from schizophrenia with hyperhomocysteinemia due to folate deficiencies. Deplin does not contain anti-psychotic or antidepressant medication. This medicine can enhance its anti-depressant effects. Deplin can also be used in other ways not mentioned in the medication guide.

Side effects of Deplin

If you exhibit any of the following symptoms of allergies: difficulty breathing, hives or swelling to lips, face throat or tongue Your symptoms could range from minor discomforts to none at all. There may be other possible side effects; to receive medical advice about them, contact your physician. Report any adverse events by calling the FDA at 1-800-FDA-1088.

Similar/related drugs

Sertraline, Trazadone, Lexapro, Citalopram, Zoloft, Cymbalta, and Folic Acid

Warnings

Please read all the instructions on the label or package of your medication. Inform your doctors about your allergies and medical conditions.Also inform them which medications you are currently taking.

Before you take this drug

If you have an allergy to Deplin, then it is best not to use Deplin.

Tell your doctor about any of the following to ensure that Deplin will be safe for you:

  • Seizures or epilepsy;
  • A history of deficiency in vitamin b12, or anemia pernicious.
  • A history of bipolar disorder

Inform your doctor whether you are breastfeeding or pregnant. You may need a different dose during pregnancy and while nursing.

How to take Deplin?

Do not exceed the dosage or duration recommended on your prescription. Take Deplin only as directed.Do not exceed the prescribed dose or duration. Do not change brands without consulting your doctor. Switching brands is not recommended without consulting your doctor. Deplin can be taken with or without food. You should follow your doctor's advice. No longer chew or crush the extended-release tablets. Take it as a whole. No other person should receive this medication, even if their symptoms match those of another. Deplin may be part of an overall treatment program that includes other medications and counseling, especially for people who suffer from depression or schizophrenia. Keep track of your counseling and medication schedules. Keep away from heat, moisture, and light.

What happens if I miss the dose?

As soon as possible, take the missed dose. If your next dose is approaching, skip the missed dose. You should not take more medicine to compensate for a missed dose.

What happens if I overdose?

A drug overdose is unlikely to result in life-threatening symptoms.

What should be avoided?

If your doctor prescribes any restrictions on foods, drinks, or activities, follow their instructions.

Interaction with other drug

Inform your doctor of all the medicines you are currently taking and those that you will stop or start using.

  • Capecitabine;
  • Fluoxetine (prozac);
  • Isotretinoin;
  • Methotrexate;
  • Methylprednisolone;
  • Pancrelipase;
  • Pyrimethamine;
  • Triamterene;
  • Trimethoprim;
  • Warfarin (coumadin, jantoven);
  • Birth control pills
  • Metformin is an oral diabetic medicine (glucophage, avandamet, metaglip, and other brands).
  • Nsaids are non-steroidal anti-inflammatory medications. These include aspirin (advil), ibuprofen, naproxen, celecoxib (aleve), diclofenac (indomethacin), indomethacin (meloxicam), and many others.
  • Seizure medicine: carbamazepine, lamotrigine, phenobarbital, phenytoin, primidone, and valproic acid.

The list below is not exhaustive. Other medications, such as prescription, over-the-counter, or herbal products, may also interact with l-methylfolate. This medication guide does not list all interactions.