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Generic name: dalteparin [DAL-te-PAR-in]
Brand name: Fragmin.
Drug class: Heparins

What is Dalteparin?

Dalteparin is an anticoagulant that aids in the prevention of blood clots. Dalteparin is used in conjunction with aspirin to avoid blood vessel problems in patients who suffer from certain kinds of angina (chest pain) or heart attacks.

Dalteparin can also be used to stop a blood clot known as deep vein thrombosis (DVT), which could result in blood clots within the lung (pulmonary embolism). The development of a DVT is a possibility following certain kinds of surgical procedures or in those who suffer from being bedridden due to an extended illness.

Dalteparin is also prescribed long-term to treat a kind of blood clot referred to as VTE that occurs in patients suffering from cancer. Dalteparin is also employed for other purposes that are not covered in this guideline.

Side effects of Dalteparin

Seek medical attention immediately in the event that you exhibit symptoms that indicate an allergy, such as asthma, hives, and swelling of your lips, face, and throat.

Seek medical attention in an emergency in the event that you exhibit symptoms of a spine blood clot: back pain and numbness, fatigue in your lower limbs, or loss of control over the bladder or bowel.

Dalteparin may cause serious side effects. Stop taking dalteparin and contact your physician immediately. If you suffer from:

  • bleeding that is unusual (nose, mouth, vagina, or rectum) or bleeding from wounds or injections; bleeding that isn't stopping;
  • Easily bruising, purple, or red spots on the skin
  • Bloody or black stools that cough up blood or vomit that resemble coffee grounds
  • Sudden weakness or a sudden weakness, headache, confusion, or issues with vision, speech, or balance;
  • Trouble breathing.

Common negative side effects of dalteparin include:

  • Low platelet levels (bruising bleeding) low platelet levels (bruising, bleeding)
  • bleeding or swelling in the area where the medication was injected.

This is not a comprehensive list of all side effects. Others could happen. Consult your physician to seek medical advice on adverse effects. You can report any side effects to the FDA at 1-800-FDA-1088.

Related drugs

amlodipine, lisinopril, metoprolol, aspirin, carvedilol, Eliquis, and Clopidogrel


It is not recommended to use the drug dalteparin when you are experiencing active bleeding or a low amount of platelets within your blood after being tested positive for a particular antibody when taking the drug.

Dalteparin could cause a severe blood clot to the spinal cord if you are subjected to the procedure of a spinal tap or some form of spinal anesthesia (epidural), in particular when you suffer from an inherited spinal defect, a history of spinal surgery or multiple spinal taps, or you take other medications that affect blood clotting, for example, blood thinners and NSAIDs (ibuprofen, Advil, Aleve, and others). This kind of blood clot may cause permanent or long-lasting paralysis.

Contact emergency medical assistance. If you are suffering from signs of blood clots in your back, pain or numbness, muscle weakness throughout your back, or loss of bladder or bowel control,

Prior to use this drug

This medicine is for you if you're allergic to dalteparin or pork products or if you suffer from:

  • uncontrolled bleeding or active bleeding uncontrolled or active bleeding
  • A history of blood clots or a low level of platelets when taking the drug heparin

Dalteparin can cause bleeding to occur more frequently, in particular if you suffer from:

  • A blood disorder that is genetic or caused by a disease
  • hemorrhagic stroke;
  • inflammation of the heart's lining (lso known as an infection of the lining of your heart, also known as endocarditis);
  • Uncontrolled excessive blood pressure;
  • the stomach, intestinal or stomach bleeding, or an ulcer or
  • Recent brain, spine, and eye surgeries

Dalteparin could cause a dangerous blood clot in your spinal cord when you have the procedure of a spinal tap or a spinal injection (epidural). This kind of blood clot can cause permanent or long-lasting paralysis. It's more likely to develop when:

  • If you suffer from a genetic spinal deformity,
  • If you suffer from a spine injury
  • If you have a spinal catheter in place or if a catheter was recently removed,
  • You have had an incident of spine surgery or multiple spinal taps;
  • You've recently experienced an epidural or spinal tap.
  • You take an NSAID (nonsteroidal anti-inflammatory drug)—ibuprofen (Advil, Motrin), naproxen (Aleve), diclofenac, indomethacin, meloxicam, and many others.
  • You take a bleeding thinner (Warfarin, Coumadin) or any other medication to prevent or treat blood clots.

Speak to your doctor if you have ever suffered from:

  • Eye issues result from eye problems caused by diabetes as well as high blood pressure.
  • severe kidney or liver illness;
  • recent stomach bleeding;
  • The levels of platelets are low in your blood.
  • If you've had epidural or spinal tap anesthesia,

It's not clear if this medication can affect a baby who is not yet born. But some forms of the drug contain a preservative, which could cause harm to newborns. Tell your doctor that you are expecting or planning to become pregnant while receiving treatment.

It is not recommended to breastfeed while taking this medication. Talk to your doctor regarding any risks.

How to take Dalteparin?

Follow the instructions on the prescription label and also read the medication guides or instructions sheets. Follow the medication precisely as directed. When it is used for DVT and blood vessel problems, the drug is usually administered daily until the bleeding problem improves. If you are treating VTE, the drug is usually used for a period of time. Dalteparin is injected underneath the skin. Healthcare professionals can teach you the proper use of the drug on your own.

Take note of and follow the instructions for use that come with your medication. Consult your physician or pharmacist to clarify any instructions. Make an injection only once you're ready to administer it. Don't use it when the medication has changed color or contains particles. Contact your pharmacist to inquire about the latest medication.

The healthcare professional will inform the body part where to inject Dalteparin. You should use a different spot every time you administer an injection. Don't inject the same spot twice in one row. It is recommended to sit or lie down for the injection. Do not inject dalteparin into muscles. Don't mix Dalteparin and other medications in the same syringe until your doctor has advised you to.

If you are using a single-dose prefilled syringe, make sure you follow the injection instructions carefully. Single-dose syringes can be found in two types, and the usage instructions differ for both.

If you require an operation or dental surgery, inform your dentist or surgeon that you are currently using dalteparin. If you require anesthesia for surgical or medical procedures, you might need to discontinue dalteparin use for an indefinite period of time. You'll need to take regular medical tests. Keep it at room temperature, free of heat and moisture.

After you've used a dalteparin bottle for the very first time, you can make use of the vial for up to two weeks. The vial should be disposed of after two weeks, regardless of whether there's still some medicine in it.

Make use of a needle and the syringe once only, and place them into a punctureproof "sharps" container. Make sure you follow local or state laws regarding how to dispose of the container. Make sure it is out of reach of pets and children.

What happens if I miss the dose?

Don't miss the dose you missed, and take the next dose at the normal time. Do not take two doses at once.

What happens if I overdose?

Get medical attention immediately, or contact us for help at the Poison Help Line at 1-800-222-1222. An overdose may cause excessive bleeding.

What should be avoided?

Do not take aspirin unless your physician recommends it as a component of the treatment. Aspirin can increase the risk of bleeding.

Avoid activities that increase the chances of sustaining injuries or bleeding. Make sure you take extra precautions to prevent bleeding when shaving or brushing your teeth.

Interaction with other drugs

Inform your doctor about any other medications you take to treat or stop blood clots.

Other medications can affect dalteparin, which includes medications that are prescribed and available over the counter, vitamins, and herbal products. Inform your physician about the medicines you are currently taking and any medication you begin or stop taking.