What is Cytogam?
CMV-IG is a sterilized solution derived from human plasma. It is a source of antibodies that aid your body in protecting itself from infections with cytomegalovirus. CMV IG is used to protect against the spread of cytomegalovirus to patients who have received one organ transplant (kidney or heart, lung, liver, and pancreas). CMV-IG could also be used to treat conditions that are not covered in this guideline.
Side effects of CMV IG
Contact emergency medical assistance. If you experience any of the following symptoms, they are warning signs of an allergic reaction: an allergic reaction that causes hives, wheezing, difficulty breathing, nausea, feeling like you're going to pass out, and swelling on your lips, face, and throat.
Cytogam can cause severe adverse effects. Stop using cytogam immediately and consult your doctor immediately. If you suffer from:
- Blue lips or pale blue appearance on your fingers or toes;
- A red blood cell disorder characterized by pale or yellowed skin, dark urine, weakness, or confusion
- Indications of a kidney issue: swelling the size of your kidney, rapid weight gain, and no or little urination;
- Chest pain, extreme difficulty breathing and wheezing, wheezing that is foamy, unsteady, or fast heart rate, or
- Symptoms of a new infection: high fever or flu-like symptoms such as mouth sores, extreme neck stiffness, headaches, being more sensitive to light nausea and vomiting,
- Indications of a blood clot: sudden weakness or numbness in speech; slurred or blurred speech; difficulties in balance or vision or balance; a sudden cough; and rapid breathing. It can also be a sign of bleeding blood—the sensation of warmth, pain, swelling, or redness on either leg or the other.
Common adverse consequences of cytogam could include:
- Chills;
- Mild nausea and vomiting;
- Joint pain;
- Lower back pain, muscle cramps, or
- Flushing (warmth of redness, warmth, or tingly sensation).
This isn't a complete list of possible side effects, and others could happen. Contact your doctor for advice regarding medical adverse effects. You can report any symptoms to the fda at 1-800-fda-1088.
Similar/related drugs
Valacyclovir, Valganciclovir, Valcyte, Letermovir, and Prevymis
Warnings
This medication is for you if you've ever experienced an allergic reaction to an immune globulin or if you suffer from immunoglobulin A (IgA) deficiency due to antibodies to IgA.
Prior to use this drug
It is not recommended to use Cytogam. If you've ever suffered an allergic reaction to an immune globulin, or if you suffer from immunoglobulin A (IgA) insufficient antibodies to IgA,
To be sure CMV IG is safe for you, inform your doctor if you are suffering from:
- Kidney disease;
- Diabetes;
- Family history or a history of the heart condition as well as stroke;
- If you are over 65 years old,
- If you've had a cold by vomiting, diarrhea, or
- If you're dehydrated or suffer from an abnormally low blood pressure,
FDA classification for pregnancy It is unknown if CMV-IG can cause harm toa baby who is not yet born. Inform your doctor if you are expecting or planning to become pregnant while taking this medication.
CMV IG is derived by removing the blood plasma of humans (part of the blood), which could be contaminated with infections and viruses. Plasma donated is tested and treated to decrease the chance of it being contaminated by infectious agents. However, there is a chance it could carry diseases. Discuss with your physician the potential risks and benefits of this drug. It is unclear if CMV IG is absorbed into breast milk or if it can harm the nursing infant. Consult your physician if you are breastfeeding a baby.
How to take CMV IG?
CMV IG is administered into a vein using an IV. The healthcare professional will provide you with the injection.
CMV-IG is typically given within 72 hours of the transplant. After that, you'll receive doses every 2 to 4 weeks following the transplant.
If you are receiving CMV IG, it is possible that you will require frequent blood tests. The kidneys may also need to be assessed
What happens if I miss the dose?
Consult your physician for instructions. If you have missed a dose of CMV Ig,
What happens if I overdose?
For medical emergencies, seek emergency medical attention or contact the Poison Help Line toll-free at 1-800-222-1222.
What should be avoided?
Don't receive a "live" vaccine while using CMV IG. The vaccine might not function at all during this period and might not completely protect you from illness. The live vaccines are measles, rubella, mumps (MMR), polio, the typhoid virus, rotavirus, yellow fever, and varicella (chickenpox), as well as the zoster (shingles) and the nasal influenza (influenza) influenza vaccine
Interaction with other drugs
CMV IG can harm your kidneys. This can be exacerbated if you take other medications, such as chemotherapy, antivirals, injected antibiotics, medications for bowel problems, medication to avoid rejection of organ transplants, injection-able osteoporosis medications, and a few arthritis and pain medicines (including aspirin, Tylenol, Advil, and Aleve).
Other medications can interfere with the immune globulin of cytomegalovirus, such as prescription and non-prescription medicines, vitamins, and herbal products. Be sure to inform your medical professionals about the medications you take now as well as any medicines you take or stop taking.
