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Generically: Naproxen Na-PROX-en Na-PROX-en [ na-PROX-en
The Class Of Drugs: Nonsteroidal anti-inflammatory drugs

What is Aleve?

Aleve is a nonsteroidal anti-inflammatory medication (NSAID). Naproxen helps by reducing the hormones that cause pain and inflammation within the body.

Aleve can be used to treat minor aches and pains related to arthritis, muscular pains, backaches, menstrual cramps, headaches, toothaches, and the typical cold. It can also be used to temporarily lower the fever.Aleve is also employed for other purposes that are not covered in this guideline.


It is not recommended to take Aleve in the event that you've experienced an allergy to aspirin or any other NSAID (nonsteroidal anti-inflammatory medication).

Naproxen may increase the risk of a fatal heart attack or stroke, particularly if you are taking it long-term, in high doses, or if you suffer from heart disease. Even those who do not have heart risk factors or heart disease could be at risk of a heart attack when taking this medication.

Do not take this medication immediately prior to or after the procedure to bypass your heart (coronary bypass grafts for arteries (CABG) or CABG).Seek medical attention immediately for chest discomfort or weakness, breathlessness, speech slurring, or difficulties with balance or vision.Aleve can cause diarrhea or stomach ulcers, which could lead to death. These issues can happen at any time while taking naproxen, particularly for older people.

Before You Take This Drug

Aleve can cause diarrhea or stomach ulcers, which could be fatal. These problems can develop at any time while taking naproxen, particularly among older adults.

You shouldn't take Aleve in the event that you are sensitive to naproxen or if you've ever suffered an asthma attack or a severe allergic reaction following taking aspirin or any NSAID.Consult a physician before giving Aleve to children younger than twelve years of age.

Talk to a doctor or pharmacist to determine if it's appropriate for you to use this medication if you suffer from:

  • Heart disease heart disease, high blood pressure, diabetes, high cholesterol, or if you smoke

  • An occurrence of a heart attack, stroke, or blood clot;

  • A history of bleeding or stomach ulcers;

  • Asthma;

  • Kidney or liver disease;

  • Fluid retention: 

  • If you are taking aspirin to stop heart attacks or strokes.

If you are expecting, then you shouldn't take Aleve unless your physician tells you not to. Taking a NSAID in the final 20 weeks before the birth could cause kidney or heart issues in the baby and possibly complications in the pregnancy.It might not be safe to breastfeed when taking Aleve. Talk to your doctor about any risks.

Aleve is not a prescription drug for people younger than two years of age. Avoid giving this medication to children without medical advice.

How to Take Aleve?

Utilize Aleve strictly as per the directions on the label or as directed by your physician. Don't take this medication in larger quantities or for longer periods than prescribed. Choose the dosage that will be effective in treating your illness.

If your child is taking this medication, tell your physician if your child's weight has changed or if there are any weight changes. Naproxen dosages are based on the weight of children, and any change could alter the dosage of your child.If you are using Aleve over a long period of time, you could require regular medical testing.

This medication can produce unusual results in certain tests. Inform any physician who treats you that you're taking Aleve.

Keep the bottle cool, away from light, moisture, and heat.Make sure the bottle is tightly shut when not in use.Check all the information about your patient, including medication guides and instruction sheets that you receive. Talk to your pharmacist or doctor about any additional concerns.

What Happens If I Miss a Dose?

Because Aleve is usually taken only in emergencies, it is possible that you are not on a dosage schedule. If you're following a regimen, take the missed dose as quickly as you can remember. Do not take any missed doses if it's nearing the time for the next scheduled dose. Don't use any extra medication to make up for the missed dose.

What Happens If I Overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help line at 1-800-222-1222.

What Should Be Avoided?

Beware of drinking alcohol. This can increase your risk of bleeding in your stomach.Avoid taking aspirin and other NSAIDs unless your doctor advises you to.

Talk to your doctor prior to using any other medications for the treatment of arthritis, pain, or fever. Also, ask your doctor about swelling, pain, or Some of the medications available at pharmacies include salicylates, aspirin, or other drugs like naproxen (such as ketoprofen or ibuprofen). The combination of certain medicines could cause you to take excessive amounts of this kind of medicine.

Consult your physician before taking an antacid. Make sure you use only the one that your doctor recommends. Certain antacids may cause the body's system to take in Aleve.

Side Effects Of Aleve

Take immediate medical care. If you are experiencing symptoms that indicate you are experiencing an allergic reaction (runny or stuffy noses, wheezing, trouble breathing, hives, or swelling in your throat or face) or a severe skin reaction (fever and throat soreness, burnt eyes, irritation, and the skin may be red or purple that blisters and peels),

Stop taking Aleve or seek out medical attention when you experience a severe drug reaction that could affect the body in a variety of ways. Symptoms may include an itch and fever, swelling of the glands, muscle pains, extreme weakness, unusual bruising, or an increase in the color of your eyes or skin.

Seek medical attention immediately. If you are experiencing symptoms of stroke or heart attack, chest pain spreading into your shoulder or jaw A sudden feeling of weakness or numbness in one area of your body; speech slurred; feeling tired.

Stop taking Aleve and consult your physician immediately if you are suffering from:

  • Breathlessness (even when exerting only a little);

  • Weight gain or swelling that is rapid

  • The very first indication of any skin rash, regardless of how slight;

  • Symptoms of stomach blood:

    bleeding, bloody or tarry stool, coughing blood, or vomiting that appears like coffee grounds

  • Liver issues:

    nausea, stomach discomfort, itching, fatigue feelings, flu-like symptoms lack of appetite dark urine, clay-colored stool, jaundice (yellowing of the eyes or skin),

  • Kidney issues:

    The result is a lack of or no urinary tract, pain or difficulty urinating, swelling of your ankles or feet, being exhausted or sluggish,

  • Red blood cells are low (anemia):

    pale skin, feeling lightheaded or short of breath, fast heart rate, difficulty concentrating,

  • Serious skin reactions:

    that cause fever, irritation of the throat or tongue, swelling on your tongue or face, burning in your eyes, and skin irritation that is followed by the appearance of a purple or red skin rash that grows (especially on the face and the upper part of the body) and can cause blisters and peeling.

Common Aleve adverse reactions could include:

  • Indigestion, heartburn, stomach pain, nausea;

  • Headache, dizziness, or drowsiness;

  • Bruising, itching, rash;

  • Swelling 

  • Ringing in your ears.

This isn't a complete list of possible side effects, and other side effects could occur.Contact your doctor for advice regarding medical effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.

Interaction With Other Drugs

Consult your physician before taking Aleve in the event that you are taking an antidepressant like citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, sertraline, paroxetine (Zoloft), trazodone, or vilazodone. The combination of any of these drugs with an NSAID could cause bleeding or bruises easily.

Talk to a pharmacist or doctor to determine if it's safe to take Aleve when you are using one of the following medicines:

  • Cholestyramine;

  • Cyclosporine;

  • Digoxin;

  • Lithium;

  • Methotrexate;

  • Pemetrexed;

  • Phenytoin or similar seizure medications;

  • Probenecid;

  • Warfarin (Coumadin, Jantoven) or similar blood thinners

  • Diuretic, also known as a "water pill";

  • Blood pressure medication, or heart 

  • Insulin or other oral diabetic medications.

This list isn't comprehensive. Other medications can be incompatible with naproxen, such as prescription and over-the-counter medicines such as vitamins and herbal products. There are not all interactions included in this guideline for medications.



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