
What is the factor IX complex?
Factor IX (nine) is a naturally occurring protein found in the blood that helps the blood form clots. Insufficient factors that clot can lead to bleeding that is not controlled since the blood does not effectively clot. The Factor IX complex is composed of four factors for clotting and other proteins. The medication is used to temporarily increase the levels of these factors in the blood to assist in the process of clotting. The Factor IX complex helps treat and stop bleeding in patients suffering from a Factor IX deficit (hemophilia B). It also helps stop bleeding from surgical or dental procedures in patients who suffer from hemophilia B. Factor IX could also be used to treat conditions not covered in this guideline.
Side effects of factor IX complex
Seek medical attention immediately. If you notice symptoms warning signs of the presence of an allergy, such as symptoms of hives or an itchy rash, rapid heartbeats, the chest becoming tight, wheezing,breathing difficulties, swelling of the lips, tongue, throat, or face.
Factor IX complex could result in serious adverse reactions. Stop using the factor IX complex and contact your physician immediately. If you suffer from:
- Being sweaty and a feeling of short breath.
- Lightheadedness that makes you feel as though you're about to pass out.
- Easily bruising; more bleeding episodes.
- Bleeding from a cut.
- Symptoms that a blood clot has formed within the lung: chest pain, rapid couging, wheezing, rapid breathing, and coughing up blood.
- Symptoms that a blood clot has formed within your leg, such as swelling, pain, or redness on one or both legs.
Common negative side effects of the factor IX complex could include:
- Headache.
- Flushing (warmth, redness, or tingly sensation).
- Nausea, vomiting.
- Fever, chills.
- Insufficiency of energy.
This isn't a complete list of all the side effects. Others could happen. Consult your physician for advice regarding medical adverse effects. You can report adverse reactions to the FDA at 1-800-FDA-1088.
Warnings
Follow the instructions on the label of your medication and the package. Inform your healthcare professionals about your medical issues, allergies, and the medicines you are taking.
Before you take this drug
Your doctor will conduct blood tests to confirm that factor IX deficiencies are your particular bleeding problem. Factor IX complex would not be a good choice for dealing with deficiencies in other factors that cause blood clotting. Your physician may ask you to undergo a hepatitis vaccine prior to when you begin using the Factor IX Complex.
To ensure the factor IX complex you are using is appropriate for you, inform your doctor if you:
- If you suffer from an autoimmune liver disorder.
- If you're allergic to latex.
- You've recently undergone surgery.
- You're scheduled to undergo surgery.
It is unclear if the factor IX complex can cause harm to a newborn baby. Inform your doctor if you are expecting or planning to be pregnant. It isn't known if factor IX complex is absorbed into breast milk or whether it can harm the nursing infant. Consult your physician if you are breastfeeding a child. Factor IX complex is not allowed to be used by anyone less than 18 years old. Factor IX complex is made of plasma from humans (part of the blood), which could be contaminated with infections and viruses. The plasma donated is analyzed and treated to decrease the chance of it being contaminated by infectious agents; however, there is still a possibility that it may carry the disease. Discuss with your physician the potential risks and benefits of this treatment.
How to take complex factor IX?
Follow the instructions on the prescription label. Do not take this medicine in greater or lesser quantities or for longer periods than prescribed. Factor IX is instilled into veins via an IV. It may be explained to you how to inject an IV at home. Don't inject yourself with the medicine if you don't know how to administer the injection correctly, and eliminate IV tubing, needles, and other equipment employed.
Always verify the strength of the medication in the package to make sure that you are using the right dosage. Clean your hands prior to preparing and administering your injection. Factor IX needs to be mixed with the aid of a liquid (diluent) prior to use. The medicine and diluent should be taken from the refrigerator and allowed to come up to room temperature before mixing the dosage. Don't heat the medication or the diluent. If you're using infusions at home, make sure that you are aware of how to blend and preserve the medication. After mixing it, gently swirl the mix and allow the medication to completely dissolve. Make use of the medicine as soon as you are able after mixing. Mixing medicine can be stored at room temperature, but you must utilize it within three hours. Don't put the mixed medicine in your refrigerator.
Prepare your dose using a syringe only after you are able to give yourself an injection. Don't use the medicine when it's changed color or appears cloudy. Consult your pharmacist about the new medications. One dose of factor IX might suffice to stop minor bleeding. If you require a second dose, make sure you wait at least 24 hours before taking the medicine again. Be sure to check your pulse before and during the injection. If you notice a change in your pulse, reduce or cease the treatment until the pulse is back to normal. Every single container (bottle) of this medication is intended for use once only. Dispose of it after one usage, even if there's still some medicine in it after you have injected your dose. Utilize an empty needle and syringe just once. Be sure to follow any local or state regulations regarding the disposal of used needles and syringes. Make sure you use a puncture-proof "sharps" disposal container (ask your pharmacist for one and what to do with it). Keep dogs and children away from the container. Wear a medical alert tag or have an ID card showing that you suffer from hemophilia. Any physician who is treating you should be aware that you suffer from bleeding or blood-clotting disorders.
If you are in need of any kind of dental surgery or procedure, be sure to inform your dentist or surgeon beforehand that you suffer from hemophilia. The body can create antibodies, or inhibitors," to the factor IX complex. When your body begins to develop antibodies, or inhibitors," to the clotting factor, the treatment becomes less effective in stopping bleeding episodes. Consult your physician. If you think this medication may not be as effective in reducing the bleeding, If you are using factor IX complex, you might require regular blood tests. Keep bebulin and its dilute solution in an airtight container in a refrigerator. Don't keep it in the freezer. Keep the profilnine and its diluting solution in a cool, dry place far from heat and moisture. Dispose of any solution or medication after the end date on the bottle has passed.
What happens if I miss a dose?
Because factor IX complex is often employed when it is needed, it is possible that you are not following a regular dosing regimen. If you're following a regimen, take the dose you missed as soon as you can remember. Do not take your missed dose if you are nearing the time for the next scheduled dose. Don't use any extra medication to replace the missed dose.
What happens if I overdose?
Get medical attention in an emergency or contact the poison help line at 1-800-222-1222.
What should be avoided?
Follow the instructions of your physician regarding any limitations on foods, drinks, or any activity.
Interactions with other drugs
Discuss with your doctor all other medications you take, particularly:
- Aminocaproic acid (Amicar).
- Tranexamic acid (Cyklokapron, Lysteda).
This list isn't complete. Other drugs can interfere with the factor IX compound. This includes prescription and non-prescription medicines, vitamins, and herbal products. The interactions of all drugs are included in this medication guideline.