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Carbamide peroxide (otic)

Generic name: carbamide peroxide (otic) [KAR-ba-mide-per-OX-ide-OH-tik]
Brand names: Auraphene-B Debrox, Ear Wax, Ear Wax Removal, Mollifene, etc. display the 18 brand names.
Dosage Form: Otic Solution (6.5 percent)
Drug class: cerumenolytics

What is Carbamide Peroxide?

Carbamide peroxide is an otic (for the ear) that can be employed to help soften and loosen the ear wax, making it simpler to get rid of. Carbamide peroxide could be utilized for reasons not mentioned in this guideline.

Side Effects of Carbamide Peroxide:

Contact a medical professional immediately. Get medical attention immediately if you notice symptoms that are warning signs of an allergic response, such as hives, difficulty breathing, and swelling of the lips, face, tongue, or throat. Carbamide peroxide could result in serious adverse side effects. Do not use carbamide peroxide and contact your physician immediately if you experience:

  • Dizziness; or
  • New or worsening problems with ear hearing

A common adverse effect of carbamide peroxide can be:

  • A crackling or foaming sound within the ear following the use of drops for the ear;
  • Hearing loss that is temporary in the short term after using the drops
  • A slight sensation of fullness or a feeling in the ear.
  • A mild mildness in the ears.

It isn't a comprehensive list of possible side effects, and there are other possible side effects. Contact your doctor for advice regarding adverse medical consequences. The best way to report adverse reactions is to call the FDA at 1-800-FDA-1088.


Do not take carbamide peroxide in the event that you've got an eardrum (ruptured the eardrum) or notice any indications of hearing inflammation or injury, for example, pain, warmth, or swelling. It can also cause drainage or bleeding.


Before you take this drug

Do not take carbamide peroxide as an otic if you are sensitive to it or if you've got holes in your eardrum (ruptured the eardrum). Speak with a pharmacist or doctor to determine if it's safe to take this drug if you are suffering from additional medical issues, including:

  • Recently, you may have had surgery or an injury to the ear. operation or injury
  • Itching, earache, or another irritation
  • drainage, discharge, or a bleed from the ear.
  • The ear may be swollen or achy around it. ears.

Carbamide peroxide is not recommended to be administered to a child less than 12 years old.

How to take Carbamide Peroxide?

Follow the directions on the label or according to the prescription of your physician. Use it in smaller doses or in larger amounts than recommended.

Carbamide peroxide is an otic that is accompanied by patient directions on how to use it safely and effectively. Make sure you follow these guidelines with care. Talk to your pharmacist or doctor for more information. Cleanse your hands prior to and after you use carbamide peroxide. For ear drops to use:

  • Lay down on your back or tilt your head to the side with your ear pointing upward. The ear canal can be opened by gently pulling back your ear and pulling it downwards upon the earlobe when administering the medicine to children.
  • Use the dropper upside-down on your ear, then drop the appropriate amount of drops in your ear.
  • It is possible to hear a bubbling noise inside the ears. It is due to the impact of carbamide peroxide. It assists in breaking up the wax in your ear.
  • Lay down on the floor or with your head bent for at least five minutes. Use a small piece of cotton to shield the ear to prevent the medications from running out. Consult your doctor's advice regarding using cotton.
  • Don't touch the tip of your dropper or place it in your ear directly. It could be dirty. The tip should be cleaned using a clean tissue, but do not rinse it with soap or water.

Carbamide peroxide can be purchased using a bulb syringe, which can be used to flush the ear canal with water. When using the bulb syringe:

  • Make sure to fill the syringe up with water that is warm to your body temperature (no more than 98 degrees F). Don't use cold or hot water. cool water.
  • Place your head in a sideways position and your ear over an empty bowl or sink. Then gently pull the ears back in order to open your ear canal. The part of the syringe's bulb in the ear's opening canal Don't insert the syringe into your ear.
  • The bulb syringe should be squeezed slowly to let the water flow into the ear. Don't squirt it without a lot of force, as you may damage your eardrum.
  • Take the syringe off and let the syringe empty into your ear and into the bowl or sink.

Avoid using carbamide peroxide for more than four days in a row. Contact your physician if you continue to experience excessive earwax following the use of this drug or if the symptoms become worse. Make sure to clean the bulb syringe after using plain water to fill it and then emptying it a few times. Avoid using cleaners such as soap or detergents. The syringe should be allowed to dry in the air. Make sure the bottle is well sealed, and keep it inside the carton at room temperature, far from heat and moisture.

Details on dosage:

Usual Adult Dose for Cerumen Removal:

5–10 drops of the solution are injected into the affected ear(s) two times a day for a period of up to 4 days. The patient must remain there for at least a few minutes so that the solution has time to get into the ear. A cotton swab can be put into the ear in order to extend the period of time the solution has contact with the cerumen.

Usual Pediatric Dose for Cerumen Removal:

Children 12 years old 1–5 drops (according to the size of the patient) from the treatment are injected directly into the affected ear(s) twice daily for up to four days (non-FDA-authorized usage). Patients should stay in the position for a few minutes so that the solution has time to reach the ear. A cotton swab can be inserted into the ear to increase the time the solution comes into contact with the cerumen.

Between 12 and 18 years old 12 to 18 years old: 5–10 drops of solution are put into the affected ear(s) two times a day for up to four days. The patient must remain at this level for a number of minutes in order to allow the solution to get into the ear. A cotton swab can be inserted into the ear to increase the time the solution is in proximity to the cerumen.

What happens if I miss a dose?

Because carbamide peroxide is employed when required and is not following a regular dosing regimen. If you're following a regimen, take the dose you missed as quickly as you recall. Do not take the missed dose if you are nearing the time of your next dose. Don't use any extra medication in order to fill the missing dose.

What happens If I overdose?

A high dose of carbamide peroxide is unlikely to pose a danger. Get medical help immediately or contact the Poison Help line at 1-800-222-1222 if you have accidentally swallowed the drug.

What should be avoided?

Beware of getting carbamide peroxide into your eyes or mouth. Use only ear drops unless your physician has advised you to.

Interaction with other drugs

It's unlikely that the other medications you consume by mouth or inject will have any effect on the carbamide peroxide in your ears. However, many medications can interfere with one another. Be sure to inform your healthcare professionals about the medicines that you take, which include medicine that is prescribed or over-the-counter, vitamins, as well as herbs.