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Aspirin, butalbital, and caffeine

Generic names: aspirin, butalbital, and caffeine (AS-pir-in, bue TAL-bi-tal, KAF-e).
Brand terms: Fiorinal, Fiormor, Fiortal, Fortabs, Butalbital Compound, Idenal, Laniroif
Dosage forms: oral capsule (325 mg-50 mg-40 mg), oral tablet (325 mg-50 mg-40 mg)
Drug class: analgesic combinations

What is Aspirin, butalbital, and caffeine?

Aspirin Butalbital, aspirin, and caffeine are combination medications for treating conditions that are caused by tension (muscle contraction) headaches. Aspirin, butalbital, and caffeine are not intended to treat multiple headaches that occur and go.Aspirin, butalbital, and caffeine are also employed for other purposes that are not listed in this guideline.

Side effects of Aspirin, butalbital, and caffeine

Contact emergency medical assistance when you are experiencing symptoms warning signs of an allergic response (hives or breathing difficulties and swelling in your throat or face) or severe skin reactions (fever and burning eyes, sore throat and skin irritation, as well as an ailment that is purple or red that blisters and peels).Do not take this medication and seek medical attention when you experience a severe drug reaction that affects various parts of your body. Symptoms may include the appearance of a skin rash and fever, swelling of the glands, muscle pains, abnormal bruising, severe weakness, or the discoloration of your eyes or skin.

Aspirin, butalbital, or caffeine can have severe adverse effects. Contact your physician immediately. If you suffer from:

  • Bloody or tarry stools
  • Vomiting blood, or vomit that resembles coffee grounds
  • Any bleeding that does not stop.

The most common side effects associated with aspirin, butalbital, and caffeine include:

  • Drowsiness

This isn't a complete list of all the side effects. Other effects may also be present. Consult your physician to seek medical advice on the effects. Report any adverse reactions directly to the FDA at 1-800-FDA-1088.


Aspirin, butalbital, and caffeine could cause a change in behavior. The misuse of these substances can result in addiction, overdose, or even death.

Before you take this drug

If you have an allergy to aspirin, butalbital, or coffee, you are suffering from:

  • A blood clotting disorder, such as hemophilia, von Willebrand's disease, or low platelets;
  • Severe vitamin K deficiency;
  • Serious chronic liver illness;
  • An extreme allergic reaction (sneezing or runny nose and wheezing) following the use of aspirin or an NSAID (nonsteroidal anti-inflammatory medication) like ibuprofen celecoxib; diclofenac, indomethacin, naproxen, Advil, Motrin, Aleve, and many others;
  • A stomach ulcer
  • Porphyria (a genetic disorder of enzymes that can cause symptoms in the nervous system or skin).

It is not recommended to be used by anyone who is younger than 18. Utilizing this medication in the case of a teenager or child suffering from influenza signs as well as chickenpox can lead to the development of a fatal or serious disease known as Reye's syndrome.

Inform your physician immediately if you have ever experienced:

  • Kidney disease or liver failure;
  • Bleeding issues;
  • A head injury or brain tumor;
  • An intestinal or stomach disorder;
  • Thyroid that is underactive;
  • Allergies;
  • An enlarged prostate or urinary problems;
  • Addison's disease (an adrenal gland disorder)

Do not take this medication while pregnant unless your physician recommends that you should. Using butalbital during pregnancy can result in withdrawal symptoms for the infant. Utilizing aspirin during the last 20 weeks could cause harm to the baby and result in pregnancy-related complications.

Do not breastfeed.

How to take Aspirin, butalbital, and caffeine?

Follow the directions on the label of your prescription and study all medication guides or instructions sheets. Choose the most effective dose to treat your condition.Butalbital can be a trigger for addiction. The misuse of the drug can lead to addiction or overdose. It can also cause death. Keep the medication away from the reach of others who might need it. Giving away or selling aspirin, butalbital, or caffeine is illegal.This medication can alter the results of certain tests. Be sure to inform any doctor treating patients that you're using aspirin, butalbital, or caffeine.The medicine is typically intended for short-term use only. It is possible to experience withdrawal symptoms in the event that you suddenly stop taking the medication after lengthy usage. Consult your physician before discontinuing the medication.Always store in a cool, dry location away from heat, humidity and light sources. Place your medication in a location that is secure and where nobody can access it incorrectly.

Details on dosage

Usual Adult Dose for Pain:

A capsule or two taken orally every 4 hours, if needed, not exceeding 6 capsules a day.
Due to its high level of physical dependence, long-term use of this medication is not advised.
The safety and effectiveness of treating headaches that are recurring with this product are not established.
Uses: To relieve the symptoms of tension (or muscle contraction) headaches.

What happens if I miss the dose?

This medication is prescribed when it is needed. If you're following a regular dosing regimen, you should skip missed doses.Do not take two doses at the same time.Don't take more than six tablets or capsules within 24 hours.

What happens if I overdose?

For medical emergencies, seek emergency treatment or contact the Poison Help Line at 1-800-222-1222. In the event of an overdose, butalbital can cause death.Overdoses can result in severe dizziness, confusion or feeling agitated, insomnia, shakes, rapid or pounding heartbeats, vomiting, stomach pain, rapid breathing, sensations of heat or ringing in the ears, weak or slow breathing, bleeding or bruises, seizures (convulsions), fainting, or coma.

What should be avoided?

Avoid driving or engaging in hazardous activities until you understand how butalbital, aspirin, and caffeine can impact your health. The way you react could be affected.Consult a physician or pharmacist prior to using any other medications for swelling, fever, and pain, as well as symptoms of the cold or flu. They could contain ingredients like aspirin (such as ibuprofen, ketoprofen, or naproxen).Beware of drinking alcohol.

Interaction with other drug

Combining this medication with other medications that cause you to feel drowsy may make this worse. Consult your physician before taking opioid medications, sleeping pills such as a muscle relaxer, or medication for anxiety and seizures.

  • Inform your physician of any other medications taken, including:
  • Methotrexate;
  • Probenecid;
  • Consider taking blood thinners such as warfarin, Coumadin or Jantoven;
  • Insulin, or oral diabetes medicine;
  • Steroid medicine such as prednisone;
  • MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine and tranylcypromine as examples;
  • Nonsteroidal anti-inflammatory drugs (nonsteroidal anti-inflammatory drugs): aspirin, Ibuprofen, aspirin (Advil, Motrin), naproxen (Aleve), Celecoxib, diclofenac, indomethacin, meloxicam, and many more.

This list isn't complete. Other drugs can interact with aspirin, butalbital, or caffeine, such as prescription and over-the counter medicines, vitamins, and herbal products. Some interactions with drugs are not listed here. are included here.




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