The Web Health


Nayzilam nasal spray

Generic Name: Midazolam (nasal) [my-DAZ-oh-lam]
Name of the Brand: Nayzilam
Drug Class: Benzodiazepines

What is Nayzilam?

Nayzilam nasal spray contains midazolam, a benzodiazepine (ben-zoe-dye-AZE-eh-peen).Nayzilam nasal spray can be described as a prescription medication prescribed for treating seizures in clusters (also known as "acute repetitive seizures") in adults and children who are at least 12 years old.

Nayzilam is a federally controlled substance (C-IV) because it could be misused and lead to dependence. Make sure to keep it in a secure place to prevent abuse and misuse. Giving away or selling the medicine could harm other people and is against the law. Inform your doctor that you've been using or have become dependent on the use of prescription or alcoholic drugs as well as street drugs.

It isn't known whether Nayzilam is safe and effective for children younger than 12 years of age.


It is not recommended to apply Nayzilam nasal sprays if you suffer from narrow glaucoma.MISUSE OF NAYZILAM CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Make sure the medication is stored in a safe place so that others are unable to access it.

Nayzilam may reduce or stop your breathing, especially if you've recently taken an opioid or alcohol, as well as other substances that may reduce your breathing. A person caring for you must seek urgent medical treatment if you suffer from prolonged pauses in breathing and if it is difficult to get up or stop breathing.

Do not stop taking Nayzilam nasal spray before consulting your physician. There is a risk of life-threatening withdrawal symptoms if you suddenly quit using the medication after long-term usage. The withdrawal symptoms can last for 12 months or more.

Seek medical assistance immediately. If you stop taking Nayzilam or experience any of the symptoms such as strange muscle movements, becoming more talkative or active, having sudden and extreme changes in behaviour or mood, hallucinations, seizures, or thoughts of suicide,

Certain people are prone to thoughts of suicide while taking Nayzilam. Speak to your doctor immediately if you notice sudden change in your behavior and mood or even thoughts of suicide.

Related drugs

  • Diastat,
  • Sympazan,
  • Diazepam,
  • Topiramate,
  • Levetiracetam,
  • Depakote,
  • Keppra

Before you take this drug

Nayzilam is not a good choice. If you are allergic to midazolam, or you are:

  • Narrow-angle glaucoma.

To be sure Nayzilam is suitable for you, inform your doctor if you've previously had:

  • Glaucoma;
  • Depression, also known as a mental disorder,
  • Suicidal thoughts, actions, or thoughts;
  • Addiction to alcohol or drugs;
  • Asthma, emphysema, bronchitis, chronic obstructive respiratory disorder (COPD), or any other breathing issues;
  • Congestive heart failure,
  • Kidney or liver disease.

Some people consider suicide when taking Nayzilam. Be aware of any changes in your attitude or signs. Your carers or family members must also be aware of unexpected changes in your behavior.

Discuss with your physician whether you're pregnant or are planning to be pregnant. If you use Nayzilam during your pregnancy, the baby may be born with withdrawal symptoms that could be life-threatening and may require medical attention for a few weeks.Consult your doctor to determine whether it is safe to breastfeed while taking this medication.

How to take Nayzilam?

Make use of Nayzilam nasal spray according to the prescription of your physician. Follow the instructions on your prescription label and review all medication manuals or instruction sheets. Do not take Nayzilam in greater amounts or for longer than what is prescribed. Inform your doctor if you notice an increase in your desire to take more of this medication.

Do not share this medication with anyone else, particularly one who has an addiction history. In the wrong hands, it could lead to addiction, overdose, or death. Place the medicine in a location away from the reach of others who might need it. Giving away or selling this medicine is against the law.Do not consume by mouth. This medicine should be used only for the nose.Make sure you are able to identify the difference between a seizure cluster and when to take this medication. Consult your physician or pharmacist with any questions.

Nayzilam Nasal spray is typically administered as a single spray in one nostril. If you have seizures after 10 minutes of using one spray, try an additional spray into another nostril.

Contact a medical professional immediately. If you continue to experience seizures following the use of this medication.It is not recommended to use another spray if you feel that your breathing is very slow after one spray.Don't use more than two sprays of Nayzilam in order to treat seizure clusters. Do not take this medicine for more than one seizure cluster every three days or for more than five seizures in a calendar month (30 days).

Don't stop taking Nayzilam nasal sprays without consulting your physician. There is a risk of developing life-threatening withdrawal symptoms if you suddenly stop using the medication after prolonged usage.

Keep it at room temperature, free of heat and moisture, and stored in a spot that is secure and where nobody can access the medicine in a way that is not safe. Place the spray bottle inside your blister until you are able to use the drug.

Details on dosage

Usual Adult Dose for Epilepsy:

Initial dosage: 5 mg (1 spray) by inhalation into one nostril.
Subsequent dose: 5 mg (1 spray) intranasally into the opposite nostril following 10 minutes in the event that the patient hasn't been able to respond to the first dose.
Maximum dose: 10 mg/day.

Usual Adult Dose for Seizures:

Initial dosage: 5 mg (1 spray) intranasally into 1 nostril ONCE
Subsequent dose: 5 mg (1 spray) intravenously in the opposite nostril within 10 minutes in the event that the patient hasn't had a response to the dose that was given at first.

Usual Paediatric Dose for Epilepsy:

12-year-olds and older:
Initial dosage: 5 mg (1 spray) by intranasal in one nostril, ONCE
Subsequent dose: 5 mg (1 spray) intranasally into the opposite nostril within 10 minutes in the event that the patient hasn't been able to respond to the first dose.
Maximum dose: 10 mg/day.

Usual Paediatric Dose for Seizures:

12-year-olds and older:
Initial dosage: 5 mg (1 spray) by intranasal in one nostril ONCE
5 mg (1 spray) intranasally into the opposite nostril within 10 minutes in the event that the patient hasn't had a response to the dose that was given initially.
Maximum dose: 10 mg/day
The drug is not recommended to treat more than one episode every three days and not more than five episodes per month.
The dose following is not recommended when the patient has difficulties breathing or in the absence of sedation, which is typically not seen in a seizure cluster.
Use: A quick treatment for episodic, stereotypical episodes of frequent seizures (e.g., seizures that are repetitive, acute, or clustered), which are different from normal seizures.

What happens If I miss a dose?

Nayzilam nasal spray can only be applied when it is needed; therefore, it is not part of an ad-hoc dosing schedule. Contact your physician if your symptoms don't improve after taking this medication.

What happens If I overdose?

For medical emergencies, seek immediate attention. You can also make a call for help at the Poison Helpline at 1-800-222-1222. A high dose of midazolam could be fatal in the event that you combine it with alcohol, opioid medication, or other substances that induce drowsiness or slow your breathing.

The symptoms of an overdose can include confusion, drowsiness, muscle weakness, loss of coordination, or even coma.

What should be avoided?

Avoid drinking alcohol. Dangerous side effects or even death could happen.

Avoid driving or engaging in hazardous activities until you understand the effects of this medicine on you. The feeling of dizziness or drowsiness may result in falls, accidents, or even serious injuries.

Side effects of Nayzilam

See a doctor immediately. If you are experiencing symptoms that indicate you are experiencing an allergic reaction with Nayzilam, such as hives, breathing difficulties, or swelling of your lips, tongue, throat, or face,

Nayzilam can slow or even stop breathing, particularly in the event that you've recently consumed an opioid drug or alcohol. Anyone who is caring for you needs to seek urgent medical treatment if you suffer from prolonged breathing, pauses in your breathing, blue-coloured lips, or if it is difficult to get up.

Contact your physician immediately if you notice any abrupt or new changes in your mood or behavior, which could include the onset of depression or anxiety, panic attacks, trouble sleeping, or When you feel angry anger, angry, or insanity and inactive and agitated, or you are contemplating taking yourself or harming your self. Consult your physician immediately in the event that you suffer from the following conditions:

Breathing that's shallow or weakUncertainty, fear, or thoughts of taking a life or hurting yourself

  • A seizure;
  • Blurred vision eyes, redness, or pain blurred vision, eye pain or redness, or seeing halos around the lights.

Common Nayzilam adverse effects could include:

  • Drowsiness;
  • Headache;
  • Nasal runniness or discomfort in your nose
  • Throat irritation.

When you stop taking Nayzilam, get medical help immediately if you are experiencing symptoms like abnormal muscle movements, becoming more talkative or active, sudden and drastic changes in your mood or behaviour, hallucinations and seizures, or suicidal ideas or behaviour.

Some patients' withdrawal symptoms can last for a period of 12 months or more after abruptly stopping the medication. Inform your doctor whether you are suffering from persistent depression, anxiety, and memory problems, as well as thinking problems, sleep problems, ear ringing, or a burning or prickly feeling or sensation on your skin.

This isn't a complete list of all the side effects. Other effects may also be present. Consult your physician to seek medical advice on the effects. You can report any symptoms to the FDA at 1-800-FDA-1088.

Interaction with other drugs

Nayzilam nasal spray, along with other medications that can reduce your breathing, could result in dangerous negative side effects or even deaths. Ask your doctor prior to using opioids, a sleeping pill, a muscle relaxer, or medication to treat seizures or anxiety.

Other medications may interfere with midazolam. This includes prescription and non-prescription medicines, vitamins, and herbal products. Discuss with your doctor all other medications you take.