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Alprostadil (injectable as well as transurethral)

Generically: alprostadil (injectable and transurethral) (transurethral and injectable) al-PROSta-dil [al-PROS-tadil]
Brand names: Caverject, Caverject Impulse, Edex, Muse, Prostin VR Paediatric, Edex Refill
Dosage forms: injectable kit (10 mcg; 20 mcg; 40 mcg); injectable powder for injection (10 mcg; 20 mcg; 40 mcg);… show all 4 dosage forms.
Drug classes: impotence agents, vasodilators

What is Alprostadil?

Alprostadil is used for treating the condition of erectile dysfunction (impotence) and also to aid in diagnosing the causes of this condition. Alprostadil can also be utilised to increase the flow of blood in infants with heart problems. This guideline focuses on the use of alprostadil by males in adulthood for erectile dysfunction.Alprostadil eases tension in blood vessels and muscles in the penis, which increases blood flow and causes an erection.Alprostadil could be used for other purposes that aren't listed in this guide.

Side effects of Alprostadil

Contact a medical professional immediately. If you are experiencing warning signs of an allergic response, such as hives, difficulty breathing, or swelling of your lips, face, and tongue,

Alprostadil may cause serious side effects. Stop taking alprostadil and contact your doctor immediately. If you suffer from:

  • A lightheaded sensation, similar to when you're about to pass out.
  • Bleeding after an injection;
  • The painful experience can last as long as 4 hours
  • An increase or worsening of pain in your penis;
  • Redness, swelling, tender lumps, a strange shape, or a curving penis

Common side effects of alprostadil can be:

  • Minor discomfort in your penis, testicles, or urethra;
  • Penis redness
  • The sensation of burning or warmth in your urinary tract.

Your partner might experience adverse effects like irritation, burning irritation, and irritation to body areas that come in contact with the penis.It's not a comprehensive description of the various negative consequences. Others could happen. Contact your doctor to seek medical advice on adverse effects. You can report symptoms to the FDA at 1-800-FDA-1088.

Similar or related drugs

ibuprofen, sildenafil, tadalafil, Advil, Cialis, Motrin, and Viagra


This guideline for medication addresses only the use of alprostadil by males in adulthood for erectile dysfunction.Get medical attention immediately in the event of an uncomfortable or prolonged erection that lasts for four hours or more.

Before you take this drug

It is not recommended to use alprostadil when you are allergic to the drug or are suffering from:

  • Sickle cell anaemia and the sickle cell disease
  • Leukaemia;
  • A tumour in the bone marrow (multiple myeloma);
  • Penis deformed or curled;
  • Penile fibrosis, also known as peyronie's disease;
  • If you have an implant in your penile
  • If you have to stay clear of sexual contact due to health reasons,

Contact your doctor if had any of the following:

  • Heart disease;
  • Either high blood pressure or lower blood pressure,
  • Issues with bleeding.

Caverject, Caverject Impulse, or Muse is not recommended for use by women or anyone who is younger than 18 years old.When using alprostadil pellets, make sure to use condoms when sex is in progress and the woman you are with is expecting or has the potential to become pregnant. Alprostadil's effects on the unborn baby during conception or during pregnancy are not understood.

How to take alprostadil?

A doctor will prescribe your first dose and show you how to make use of the medication on your own.Follow the instructions on your prescription label and go through all the medication guides. Follow the medication exactly as prescribed.Alprostadil is only used for emergencies. A erection can occur in between 5 and 20 minutes and last for up to 60 minutes.The injection of alprostadil is administered to the penis's side.Alprostatil Transurethral Pellet is a very small suppository that is introduced into the urethra, opening the penis (the urethra).Don't use more than two pellets in a single day. Do not exceed three injections per week. A minimum of 24 hours should be allowed between injections.Consult your physician or pharmacist for help if you aren't sure how to make use of the injection.Make an injection just when you are prepared to give it. Contact your pharmacist if the medicine is cloudy, changes colours, or contains particles.Don't reuse a needle or syringe. Put them in an impervious-to-punch "sharps" container and dispose of it in accordance with the laws of your state or municipality. Make sure it is out of pet's reach and away from children.Contact your physician. If a needle is broken during the injection of the drug alprostadil, If you can grasp the broken part and remove the needle immediately,Your doctor should examine you every three months to make sure alprostadil does not cause adverse consequences for your penis.

Storing alprostadil:

  • Maintain the pellets inside their foil pouches inside the freezer. The pouch can be stored in a cool, dry place for up to fourteen days. Be sure to keep it away from freezing temperatures or extreme temperatures. Don't store anything in a closed car or in luggage during travel.
  • Store alprostadil injection vials at room temperature. The strength of 40 micrograms is best used in 3 months, or by expiration date. Deadline for expiration in the package.
  • After mixing the Caverject injection, store the mixture at room temperature and take it out for 24 hours.

Do I be concerned if I miss a dose?

Because alprostadil is only used in the event of need and is not a daily dosing schedule, it doesn't need a regular dosing schedule.

What will happen if I take excessively?

For medical emergencies, seek emergency medical attention or contact the Poison Help Line toll-free at 1-800-222-1222.The overdose may cause fainting or a painful and long-lasting erection.

What should be avoided?

Avoid driving or doing any hazardous activity if you are feeling lightheaded.Alprostadil does not safeguard you from sexually transmitted infections. Discuss with your doctor ways to stop the transmission of disease when you are having sex. Sharing needles for medicine or drugs is never a good idea.

Interaction with other drugs

Discuss with your doctor your other medications, particularly:

  • Other medications injected into the penis
  • Heparin, warfarin, coumadin, and jantoven

This list isn't complete. Other medications may interact with alprostadil. This includes medications that are prescribed and available over the counter, vitamins, and herbal products. There are many possible interactions between drugs, which are listed here.