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Advil Cold and Sinus

Generic Name: Ibuprofen and pseudoephedrine [EYE-bue-pro-fen-and-SOO-doe-ee-FED-rin]
Names of Brands: Advil Cold and Sinus, Advil Cold and Sinus Liqui-Gel
Classification of Drugs: Upper respiratory combinations

What is Advil Cold & Sinus?


can be described as an anti-inflammatory non-steroidal drug (NSAID). Pseudoephedrine can be used as an anti-congestant.

Advil Cold & Sinus is a combination medication that treats stuffy sinuses, nasal congestion, cough, pain, or fever that are caused by the typical cold and flu.Advil Cold and Sinus could also be prescribed for other purposes not mentioned in this medication guide.

Side Effects Of Advil Cold & Sinus?

Contact a medical professional immediately. If you notice symptoms warning signs of an allergic reaction (sneezing and runny nose, wheezing, hives, difficulties breathing, swelling on your throat or face) or an extreme skin reaction (fever or sore throat, burnt eyes, irritation, as well as a red or purple eruption with peeling and blisters),Take immediate medical care. If you are experiencing symptoms of an attack on your heart or stroke: chest pain spreading into your shoulder or jaw, suddenly feeling numb or weak in one area of your body, slurred speech, leg swelling, and feeling tired,

Stop taking Advil for colds and sinuses and contact your doctor immediately if you are suffering from:

  • Insomnia, extreme dizziness,

    severe ringing of your ears, extreme dizziness, and feeling like you're about to faint;

  • Fast, pounding, or uneven heartbeat;

  • Bleeding or bruising (nosebleeds and bleeding gums);

  • An itch on the skin, regardless of how minor;

  • Indications of stomach bleeding: bloody or tarry stool, and vomiting blood or vomiting that appears like coffee grounds

  • Issues with the liver: loss of appetite; stomach discomfort (upper right side); fatigue; itching; the dark color of urine; stools with clay; jaundice (yellowing of the eyes or skin);

  • Kidney issues: little or no urine output, swelling of your ankles and feet, and feeling exhausted or weak;

  • Nerve issues—fever, headache, neck stiffness, chills, increased sensitivity to light, seizures (convulsions).

Common adverse side effects of Advil for colds and sinus infections could include:

  • Diarrhea, constipation;

  • Headache, dizziness, drowsiness, weakness;

  • Uneasy stomach, nausea, vomiting, and lack of appetite

  • Experiencing anxiety or excitement;

  • Sleep problems (insomnia);

  • Flushing (warmth or redness) or tingly sensation.

This is not a comprehensive list of possible side effects, and other side effects could occur. Contact your physician for advice regarding medical effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.


Ibuprofen may increase the risk of having a fatal cardiac attack as well as a stroke. Avoid using this medication prior to or following heart bypass surgery (coronary artery bypass graft, also known as CABG). Ibuprofen can also trigger bleeding in the stomach or intestines that can be fatal.

Before You Take This Drug

Ibuprofen may increase the chances of suffering a fatal heart attack or stroke, even if you do not possess any risks. Avoid using Advil for colds and sinuses just prior to or following coronary bypass surgeries (coronary artery bypass graft, also known as CABG).

Ibuprofen can also trigger stomach or intestinal bleeding, which can be fatal. These issues can happen at any time while taking Advil for colds and sinus infections, especially among older adults.It is not recommended to use this medication if you are allergic to pseudoephedrine or ibuprofen or if you've ever experienced an asthma attack or a severe allergic reaction when using aspirin or an NSAID.

Don't use Advil for colds and sinus infections if you've taken an MAO inhibitor within the last 14 days. A potentially dangerous interaction between drugs could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine, and others.Ibuprofen should not be given to any child under 12 years of age.

Ask your doctor or pharmacist for a recommendation on whether this medication is suitable for you if you previously had:

  • Coronary disease, high blood pressure, high cholesterol, diabetes, or if you smoke

  • A coronary heart attack, stroke, or blood clot

  • Stomach ulcers or bleeding

  • Asthma;

  • Kidney or liver disease;

  • An thyroid disorder;

  • Diabetes

  • An increase in prostate and urinary problems.

If you are expecting, then you shouldn't take Advil for colds and sinuses unless your doctor has instructed you not to. Taking an NSAID in the final twenty weeks of pregnancy may cause kidney or heart problems for the unborn baby and may cause complications during the pregnancy.

Consult your doctor prior to taking this medicine if you are nursing.

How to Take Advil Cold & Sinus?

Take it exactly as indicated on the label or as directed by your physician. A high dose of ibuprofen may cause damage to your stomach or intestines.Consume this medicine by mouth or with milk to ease gastric upset.

Contact your physician if you are suffering from a fever that lasts more than three days, if you experience new symptoms, or if your illness doesn't improve after using this medication for seven days.If you require surgery, inform the doctor ahead of time if you've had this medicine in the last few days.Keep at room temperature, away from heat and moisture.

What Happens If I Miss a Dose?

Because Advil for colds and sinuses can be prescribed for emergencies, it is possible that you are not following a regular dosing regimen. Don't miss any dose in the event that it's nearing time to get the next dose. Do not take two doses at once.

What Happens If I Overdose?

Get medical attention in an emergency or contact the poison help line at 1-800-222-1222.

The symptoms of an overdose can include stomach pain, vomiting, diarrhea, ringing in your ears, extreme tiredness, agitation, sweating and sweating blood, as well as shallow or weak breathing, fainting, or seizures (convulsions).

What Should be Avoided?

Do not drink alcohol. This can increase the chance of bleeding from your stomach.

Talk to your doctor or pharmacist prior to using any other cold or cough medications that may have similar components.

Interaction With Other Drugs

Talk to your doctor prior to taking Advil for colds and sinuses if you are taking any antidepressants. Taking certain antidepressants together with an NSAID can cause bleeding or bruising.

Speak with a pharmacist or doctor before taking Advil Cold & Sinus with any other medication, particularly:

  • Lithium;

  • Methotrexate;

  • The blood thinners (warfarin, coumadin, and Jantoven);

  • Blood pressure or heart medication such as diuretics or "water pills";

  • Steroid medicine (such as prednisone).

This list is not comprehensive. Other medications can affect Advil Cold and Sinus, including prescription and over-the-counter medications, vitamins, and herbal remedies. There are many possible interactions between drugs. are included here.




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