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Adasuve Inhalation

Name of the generic: loxapine (inhalation) (inhalation) LOX-a-peen [LOX-a-peen]
Name of the brand: Adasuve
Classification of drugs: miscellaneous antipsychotic agents

What is Adasuve Inhalation?

Adasuve is an antipsychotic medicine that alters the behavior of the brain's chemicals.

Adasuve powder for inhalation is utilized to manage anxiety caused by schizophrenia or bipolar disorder.

Adasuve is administered only in a clinic or hospital environment where breathing issues can be treated quickly.


It is not recommended to use Adasuve inhalation when you suffer from breathing problems that may result in the condition known as bronchospasm (such as asthma or COPD) or if you're currently struggling to breathe due to wheezing and coughing. Do not take this medication if you've suffered breathing difficulties when you used it previously.

Adasuve breathing can trigger bronchospasm (wheezing and chest tightness, shorter breath), which can cause severe lung problems or make your breathing cease. This medicine must be administered in a clinic or hospital in a setting where your physician can promptly manage any serious side effects that occur.

This medication has not been approved for older adults suffering from dementia-related psychosis.

Before You Take This Drug

It is not recommended to treat with Adasuve in the event that you are allergic to the loxapine compound or amoxapine or suffer from:

  • Trouble breathing, coughing, and wheezing;

  • An asthma history, chronic obstructive pulmonary disease (COPD), or any other lung issues;

  • A breathing disorder that you're currently treating using medications or

  • There is a history of asthmatic bronchospasm following the use of Adasuve.

Loxapine could raise the chance of death for elderly patients suffering from psychosis related to dementia and is not approved for use in this manner.

To ensure that Adasuve is suitable for you, Inform your doctor if you have ever experienced:

  • Epilepsy or any other seizure disorder

  • Excessive (or high blood pressure)


  • Glaucoma;

  • Urination issues;

  • Parkinson's disease;

  • Heart disease;

  • A heart stroke or stroke.

  • If you drink alcohol or take street substances.

Inform your doctor if you are expecting or becoming pregnant. Utilizing antipsychotic medications in the final 3 months of pregnancy can cause breathing issues or feeding problems. It could also cause withdrawal symptoms in the infant.

How to Take Adasuve?

Adasuve is typically administered each day, if necessary.

A doctor will prescribe this medication in a clinic or hospital environment where you can be promptly treated if adverse side effects are observed.

Healthcare professionals can instruct you on how to utilize the device known as Adasuve.

The inhaler has an indicator light that is green on one side and an opening at the end. When the pull tab has been removed and the light turns green, it will switch on, indicating it is ready to use.

If the green light is turned on, it is imperative to use an inhaler within 15 minutes, or the device will stop working. Do not attempt to use the inhaler when the green light has gone off.

If you are using the Adasuve Inhaler device, you might hear a click sound, and your device could feel warm. These are normal features. Once you've inhaled your dose, that green light should switch off to indicate that the entire dose was used.

You will be closely monitored for at least 1 hour following the use of Adasuve to ensure that you don't have breathing issues.

Details on Dosage 

Use: To treat schizophrenia. Usual Adult Dose for Agitated State:

10 mg via orally inhalation, once per 24 hours


To minimize the risk of bronchospasm, all patients should undergo an examination and screening prior to administration.

This medication must be prescribed by a health professional only within an enrolled healthcare facility.

Use: To treat the acute agitation that is associated with bipolar I disorder or schizophrenia.

What Happens If I Miss a Dose?

Because Adasuve inhalation is only for emergencies, you could need just one dose. Adasuve is typically not administered more than once within 24 hours.

What Happens If I Overdose?

Since the medicine is prescribed by a medical expert in a medical environment, the risk of overdose is less likely to occur.

What Should be Avoided?

Avoid operating machinery or driving until you are aware of the effects of this medication on your body. Do not get up too quickly from lying or sitting in a position where you could be dizzy. The feeling of dizziness or excessive drowsiness may cause fractures, falls, or other injuries. Avoid drinking alcohol.

Side Effects of Adasuve

See a doctor immediately. If you are experiencing symptoms that you are experiencing an allergic reaction, Adasuve: hives, breathing difficulties, or swelling of your lips, face, and tongue.

Inform your caregivers immediately. If you suffer from:

  • A feeling of lightheadedness, as if you're about to pass out.

  • Blurred vision blurred vision, tunnel vision, eye pain, or seeing halos of light sources;

  • The bronchospasm (wheezing, chest tightness, cough, difficulty breathing);

  • Very little or no urine;

  • A seizure (convulsions); or

  • Extreme nervous system reactions severe nervous system reaction:

    extremely strenuous (rigid) muscles with high fever, sweating, and confusion; rapid or irregular heartbeats; tremors; and a feeling that you could be snoring.

Common Adasuve side effects include:

  • Drowsiness

  • Sore throat

  • Unusual or unpleasant flavor on the tongue.

This isn't a complete list of all the side effects. Other effects may also be present. Contact your doctor to seek medical advice on adverse effects. You can report symptoms to the FDA at 1-800-FDA-1088.

Interaction with Other Drugs 

The use of Adasuve along with other medications that make you sleepy or slow your breathing could result in dangerous negative side effects or even the death of a person. Ask your doctor prior to using an opioid medication, a sleeping pill, muscle relaxers, or medication for anxiety or seizures.

Inform your doctor about any other medications you take, particularly

  • Medication for treating depression, mood disorders, anxiety, or mental illness

  • Cold or allergy medication (Benadryl and many others);

  • Medicine for treating Parkinson's disease

  • Medicine to treat stomach disorders, motion sickness, and IBS;

  • Medicines to treat an overactive bladder treatment for overactive bladder

  • The medications for asthma are bronchodilators.

This list isn't complete. Other drugs can interact with loxapine. These include prescription and over-the-counter medicines, vitamins, and herbal supplements. There are many possible interactions between drugs. are listed here.