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Acetohydroxamic acid

Generic Name: Acetohydroxamic acid [ a-sweet-oh-hye-drox-am-ok-as-id ]
Name of the Brand: lithostat
Dosage Form: Oral tablet (250 mg)
Classification of Drugs: Miscellaneous genitourinary tract agents

What is Acetohydroxamic acid?

Acetohydroxamic acid prevents the accumulation of ammonia in the urine, which could result from a bladder problem. Ammonia levels in urine that are elevated can lead to the development of kidney stones.Acetohydroxamic acid is utilized to help keep ammonia levels in urine down in patients who suffer from a particular kind of chronic bladder condition.

Acetohydroxamic acid isn't an antibiotic; it isn't a treatment for the condition by itself. Acetohydroxamic acid can be a part of a regimen that could also comprise antibiotics to treat inflammation as well as operations to eliminate kidney stones. Take your doctor's directions very carefully.Acetohydroxamic acid could be utilized for any purpose not mentioned in this guide.


It is not recommended to use acetohydroxamic acid if you have kidney problems or if there are bladder issues that haven't been examined by a physician.

Acetohydroxamic acids can cause harm to the unborn child or lead to birth problems. Avoid using the acid acetohydroxamic if you're pregnant or not taking contraceptives.

Side effects of Acetohydroxamic acid

Contact a medical professional immediately. If you experience one of the following symptoms that indicate an allergic reaction: symptoms of hives: breathing difficulties and swelling on your lips, face, and tongue.

Mild Side Effects

  • Heartbeats that pound or beats that flutter in your chest
  • Indications of a blood clot within your leg, such as pain in the leg, swelling, warmth, or redness of either or both legs,
  • Symptoms of a red blood cell disorder: yellow or pale skin, dark-coloured urine, the appearance of fever, weakening, or confusion.

Advance Side Effects

  • Headache in the initial 2 days following treatment.
  • Skin eruption that causes warmth, tingling, or the appearance of redness (especially when you consume alcohol and take acetohydroxamic acid);
  • An upset stomach, nausea, and loss of appetite.
  • Depression;
  • Anxiety and tremors as well as
  • Hair loss.

This is not an exhaustive listing of all side effects. There are other possible side effects. Contact your doctor to seek medical advice on adverse effects. It is possible to report any side effects to the fda by calling 1-800-fda-1088.

acetohydroxamic acid's side effects (more detail)

Before You take This Drug

Do not use acetohydroxamic acid if you're sensitive to it or if you suffer from:

  • Kidney disease
  • Bladder issues that haven't been analyzed by a physician through lab tests
  • If you're expecting or aren't using contraceptives.

In order to ensure that acetohydroxamic acid is not harmful to you, consult your physician. If you are suffering from

  • Liver disease;
  • Hemolytic anemia (a deficiency in red blood cell count) is also known as
  • A weak immune system.

Fda pregnancy category x this medication can cause harm to an unborn child or even result in birth problems. Don't use acetohydroxamic acid if you're expecting. Use effective birth control measures to stop pregnancy when using acetohydroxamic. Inform your physician immediately if you find yourself pregnant or if you cease taking birth control for reasons other than this medication.

It's not clear if the acetohydroxamic acid is absorbed into breast milk or if it can harm a breastfeeding baby. Do not feed your baby while taking this medication.

How to Take Acetohydroxamic acid?

Make sure you follow all the instructions on the prescription label. Sometimes, your doctor will alter your dosage in order to make sure that you are getting the most effective outcomes. Avoid taking acetohydroxamic acid in smaller or larger quantities or for longer periods than recommended.Consume acetohydroxamic acid with an empty stomach at least 1 hour prior to or 2 hours following a meal.It is generally used every 6–8 hours. Take care to follow the instructions of your physician.Don't share this medication with someone else who has the same symptoms as you do. Acetohydroxamic acid can be used by people suffering from a specific type of bladder infection.If you're using acetohydroxamic acid, it's possible to require regular tests of your urine and blood.

You should take this medication for the maximum prescribed amount of time, regardless of whether you have any symptoms of bladder infections. Acetohydroxamic acid isn't an antibiotic and cannot treat an infection caused by bacteria on its own. You should take your antibiotics according to the directions.There is a possibility that you'll need some time with acetohydroxamic acid.Place the bottles in a cool, dry place free of heat and moisture. Make sure the bottle is tightly sealed during storage.

Details of dosage

Usual adult dose for urinary tract infection:

Dosage for the first dose: 12 mg/kg orally daily, every 6–8 hours
dosage for maintenance: 250 mg orally up to four times per day for an overall daily dosage of 10 to 15 mg/kg/day.
Maximum dosage: 1.5 g per day (regardless of weight).
a long-term regimen of treatment might be necessary to maintain the inhibition of urease if a urea-splitting disease is evident.
Experience with this drug will not last beyond 7 years.
Treatment: used as an adjunctive treatment in patients suffering from chronic urinary infections that split urea. The drug's purpose is to reduce urinary ammonia as well as alkalinity. It shouldn't be used to replace surgical therapy (for patients suffering from stones) or treatment with antimicrobials.

Usual pediatric dose for urinary tract infection:

10 mg/kg daily orally, with 2 or 3 separate doses, for up to 1 year
Children with chronic, irresistible urea-splitting urinary infections may get better results from this medication; however, research on dosages and intervals of doses for the children hasn't been conducted.
Close monitoring of the patient and histologic condition is suggested.
The adjustment of doses to lower or higher amounts could be necessary to achieve the maximum therapeutic result and/or reduce the chance of adverse negative effects.
Treatment: used as a treatment for patients suffering from persistent urea-splitting urinary tract infections. The purpose of this drug is to reduce urinary ammonia as well as alkalinity. However, it is not recommended to use it as a substitute for surgery (for those with stones) or treatment with antimicrobials.


What Happens if I Miss a Dose?

You should take the dose you missed immediately after you recall it. Do not take your missed dose if you think you are nearing the time for the next dose. Avoid taking extra medications to fill in the missing dose.

Make sure you take acetohydroxamic acid on a full stomach.

What Happens if I Overdose?

For medical emergencies, seek emergency treatment or dial for help at the poison help line at 1-800-222-1222.The symptoms of an overdose can include general unwellness, vomiting, and feelings of anxiety or nervousness.

What should be Avoided?

There is a possibility of one of these skin reactions or flushing (warmth and redness or a tingly sensation) when you drink alcohol and take acetohydroxamic acid.Consult your physician before you take any supplement or vitamin that contains iron.

Interaction with other Drugs

Certain other medications may interfere with acetohydroxamic acid, which includes prescription or over-the-counter medications, vitamins, and natural products. Inform your medical professionals about the medicines you are currently taking or any other medicine that you are about to start or stop taking.





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