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Generic name: varicella zoster immune globulin [VAR-i-SELL-a-ZOS-ter-im-MUNE-GLOB-ye-lin]
Drug class: immune globulins

What is Varizig?

Varicella zoster (commonly referred to as chickenpox) is a very common childhood disease that triggers fever as well as skin eruptions and the appearance of blisters filled with fluid on the skin. The symptoms of chickenpox are usually mild; however, they can be fatal or serious in infants, adults, and those with an insufficient immune system. It can result in serious skin infections or breathing issues, as well as brain damage. Death.

When the varicella virus is activated at an adult age, it could trigger herpes zoster (also known as shingles), which can cause painful skin infections, blisters, extreme neuropathy, and issues with vision or hearing that may be present for months or even years.

The spread of chickenpox can be passed between people through the air or by getting into contact with the fluid that is left from an open chickenpox blister.Varizig is a medication used by children, adults, and infants (including premature or newborn infants) who are at risk of becoming severely sick due to exposure to the varicella zoster. Varizig can also be used during pregnancy.

Varizig is prescribed following exposure to people who have come into contact with the varicella virus. It can prevent symptoms from getting severe or even life-threatening.This medicine is not able to cure an active disease that is already present in the body.Varizig is also employed for other purposes that are not covered in this guideline.

Side effects of Varizig

Contact a medical professional immediately. If you are experiencing symptoms or warning signs of an allergic response, such as difficulty breathing, hives, or swelling of your lips, face, tongue, throat, or face,

Varizig may cause serious side effects. Contact your doctor immediately. If you suffer from:

  • Indications that a blood clot has formed within the brain, such as sudden weakness or numbness (especially on one side) and slurred speech. Issues with balance or vision;
  • Indications for a blood clot inside the lung or in the heart chest pain rapid heart rate rapid heart rate, breathing, wheezing or sneezing, rapid breathing, and coughing up blood
  • Indications for a blood clot on your leg, such as swelling, pain, redness, or warmth in either or both legs;
  • Symptoms of a new infection: fever chills, flu symptoms, oral sores, pain when swallowing.

The risk of side effects is more common in older people.

Common negative side effects of Varizig can include:

  • Headache
  • There was pain where the medicine was injected.

This list does not represent all potential side effects; other possible reactions could occur and should be discussed with your healthcare provider for medical advice or reported directly to the FDA at 1-800-FDA-1088.


Follow the instructions on your prescription label and the package. Be sure to inform your health care providers about your allergies, medical conditions, and all medications you take.

Before you take this drug

It is not recommended to treat Varizig if:

  • You've experienced an allergic reaction to immune globulin
  • You suffer from an immunoglobulin A (iga) deficit due to antibodies to iga.

Consult your doctor if you have recently received a "live" vaccine. The vaccine might not be effective after receiving Varizig. Live vaccines comprise measles, Mumps, measles, rubella (MMR), Polio, typhoid varicella, yellow fever (chickenpox), Zoster (shingles), and the nasal influenza (influenza) vaccine.

To be sure that Varizig is suitable for you, inform your doctor if you suffer from:

  • Coronary condition; coronary artery disease (hardened arteries);
  • A bleeding or blood clotting disorder;
  • Blood circulation issues;
  • An antecedent that suggests stroke, blood clots,
  • A condition that requires you to be currently on the bed to rest.

It's not clear if Varizig could affect a newborn baby. The fact is that chickenpox can lead to birth defects, low birth weight, or even a serious infection in the infant. So, this medication could be administered during pregnancy if you are at an elevated risk of infection by the varicella zoster virus.It isn't known if varicella zoster immunoglobulin is present in breastmilk or the risk to nursing babies. Inform your doctor if you are breastfeeding your baby.

Varizig is created from the human plasma (part of the blood), which could be contaminated with viruses and other infectious agents. The plasma donated is examined and treated to decrease the chance of it being contaminated by infectious agents. However, there is a slight chance that it can be a carrier of diseases. Consult your physician about the dangers and benefits of this treatment.

How to take Varizig?

Varizig is an injection into muscles. A doctor will administer the injection.Varizig should be administered immediately (within the first 96 hours) following the time you've been exposed to the varicella zoster.

The medication is usually administered only once. However, in certain instances, your physician may suggest another dose, particularly when you have been exposed to varicella zoster within 3 weeks of the immune globulin injection.A single dose could require injection in more than one location on your body, based on the size of your body. Doses for varizig depend on weight.

What happens if I miss the dose?

Because Varizig is usually only administered once, you're unlikely to skip a dose. Inform your doctor if you are not receiving all the recommended doses.

What happens if I overdose?

Get medical attention in an emergency or contact the poison help line at 1-800-222-1222.

What should be avoided?

Follow your doctor's advice regarding any restrictions regarding drinks, food, or activities.

Interaction with other drug

Other medications may affect varicella zoster immunoglobulin, which includes prescription and over-the-counter medicines, vitamins, and herbal remedies. Be sure to inform your health professionals about the medicines you take in the present and about any medication that you decide to stop or change your use of.