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A-Methapred (injection)

Generic name: methylprednisolone (injection) [METH-il-pred-NIS-oh-lone]
Brand names: DEPO-Medrol, SOLU-Medrol, A-Methapred injection
Drug class: glucocorticoids

What is A-Methapred?

A-Methapred is a steroid that blocks the release of substances within the body that trigger inflammation.A-Methapred can be used to treat various inflammatory conditions, like arthritis and psoriasis. It also treats lupus, ulcerative colitis, allergies, gland (endocrine) disorders, and conditions that can affect the eyes, skin, lungs, stomach, and blood cells.A-Methapred is also employed for other purposes that are not covered in this guideline for medication.

Side effects of A-Methapred

Contact a medical professional immediately in the event that you exhibit symptoms that indicate an allergy, such as symptoms of hives, breathing difficulties, and swelling of your lips, face, and tongue.

A-Methapred can cause severe adverse effects. Consult your doctor immediately if you are suffering from any of the following:

  • Blurred vision blurred vision, pain, or seeing a lot of light sources;
  • Breathlessness (even when exerting only a little), swelling, and rapid weight gain.
  • Extreme depression severe depression, personality changes, abnormal thoughts or behaviour;
  • Unusual back pain that is new in the leg or arm and in your lower back
  • Extreme abdominal pain expanding to your back, along with stomach cramps;
  • Bloody or tarry stool that coughs up blood or vomit that resembles coffee grounds
  • A seizure (convulsions);
  • Lower potassium—leg cramps, constipation, irregular heartbeats, fluttering around your chest, thirsty or increased need to urinate, tingling or numbness, or tingling feeling.

A-Methapred could affect growth in children. Consult your physician if you feel your child isn't growing at a normal pace while taking A-Methapred.

Common adverse effects of A-Methapred could include:

  • Weight increase (especially around your face or in your upper back or torso);
  • Slow wound healing
  • Muscle pain or weakness;
  • Thinner skin, greater sweating;
  • Stomach discomfort, bloating;
  • Headache
  • Changes in your menstrual cycle

This isn't a complete list of all the side effects. Others could happen. Consult your physician to seek medical advice on the effects. If you have any concerns, report the allergic reactions or symptoms to FDA by calling 1-800-FDA-1088.

Similar or related drugs

Xolair , Simponi , Nucala , aspirin , prednisone , ibuprofen , albuterol


It is possible that you will not be eligible for an A-Methapred treatment if you have a fungal infection.

Prior to use this drug

You shouldn't be treated with A-Methapred if you are sensitive to it. It is possible that you will not be able to take the medication when you suffer from an infection that is a fungal illness.A-Methapred may reduce your immune system's strength, which makes it more likely for you to develop an infection. Steroids can also make an infection that you already have or revive an infection you had previously. Discuss with your doctor any infection or illness you have experienced in the last few weeks.

Inform your doctor if you were ever diagnosed with:

  • Heart disease, high blood pressure;
  • A thyroid disorder
  • Diabetes;
  • Glaucoma or cataracts
  • Kidney disease;
  • Cirrhosis or another liver disease;
  • Seizures, epilepsy, or a recent head injury;
  • Either in the past or at present; tuberculosis, whether present or past;
  • Eye herpes infection;
  • A condition known as "scleroderma";
  • Stomach ulcers stomach ulcers, ulcerative colitis, diverticulitis, or a recent digestive surgical procedure;
  • An infection caused by a parasite that causes diarrhoea (such as threadworms);
  • Psychosis, also known as schizophrenia;
  • Osteoporosis or low bone mineral density (steroid medications can increase the chances of losing your bone);
  • An illness of the muscles, like myasthenia gravis
  • An electrical imbalance (such as a low level of potassium present in the blood)

It is unclear if A-Methapred could harm an unborn baby. Inform your doctor if you are expecting or planning to be pregnant.Breastfeeding is not advised during the use of A-Methapred.

How to take

A-Methapred is injected into muscles or soft tissues in a skin lesion, into the area around joints, or into the vein. The healthcare professional will give the injection.Steroid medications can degrade your immune system, which makes it more difficult to contract an infection. Contact your doctor if you notice any indications of illness (fever, chills, or body pains).If you've had a major operation or an injury that is severe, the A-Methapred dosage requirements could be altered. Be sure that any physician caring for you is aware that you're taking this medication.If you are taking this medicine for the long term, you may require vision tests and medical tests.

What happens if I miss the dose?

Consult your physician for further instructions in the event that you don't make an appointment to see your A-Methapred.

What happens if I overdose?

Get medical attention in an emergency or contact the Poison Help Line toll-free at 1-800-222-1222.

What should be avoided?

Don't receive the "live" vaccine while using A-Methapred. These live vaccinations comprise measles, rubella, mumps (MMR), and rotavirus. yellow fever, typhoid varicella (chickenpox), as well as the zoster (shingles) and the nasal virus (influenza) vaccination.Beware of being around those with illnesses or suffering from illnesses. Contact your doctor to get preventive treatment in the event that you have been exposed to measles or chickenpox. These illnesses can be very serious and even fatal for those who use A-Methapred.

Interaction with other drugs

There are times when it's not recommended to take certain medications simultaneously. Certain drugs may affect the blood levels of other medications that you are taking. This could create side effects or render the drugs less effective.Many drugs can influence A-Methapred. This includes over-the-counter and prescription medications, vitamins, and herbal supplements. The interactions between these products are not included in this list. Inform your doctor of all the medications you are currently taking and any medication you begin or stop taking.