What is Hydroxyprogesterone?
Hydroxyprogesterone is a type of progestin. It is a synthetic form of the female hormone known as progesterone. Hydroxyprogesterone can be used to reduce the chance of having a premature birth in women who have had a premature child. Hydroxyprogesterone is not able to end the premature birth that has already started. Hydroxyprogesterone should not be used by women who are expecting more than one infant (twins, triplets, twins, etc.). Hydroxyprogesterone can also be used for reasons not mentioned in this medication guide. There is no evidence that the Makena brand name has been taken off the market across the U.S. If there are generic versions of this item that were approved by the FDA, there may be alternatives that are generic.
Side effects of Hydroxyprogesterone
Contact a medical professional immediately. Get medical attention immediately if you notice symptoms or warning signs of an allergic reaction, such as itching, hives, breathing problems, or swelling of your lips, face, and tongue. Makena Auto-Injector may cause serious side effects. Contact your physician immediately if you experience:
- Bleeding, swelling, oozing, or a worsening of pain in the area where the injection was administered.
- Jaundice (yellowing of the eyes or skin).
- Signs associated with symptoms of depression (sleep issues, depression, fatigue, mood swings).
- Swelling in your ankles, hands, or feet.
- Elevated blood pressure; severe headache; blurred vision; tension in your neck and your ears. anxious, nosebleeds.
- Indications of a blood clot: sudden weakness or numbness, problems with speech or vision, swelling, or redness in the leg or arm.
Common adverse consequences of Makena auto-injectors could include:
- Itching, pain, swelling, a rash, or a lump at the site where the medicine was injected.
- Nausea.
- Diarrhea.
This isn't a complete list of possible side effects, and other side effects could be present. Contact your physician to seek medical advice on the effects. You may report any adverse reactions to the FDA at 1-800-FDA-1088.
Similar/related drugs
progesterone, terbutaline, prometrium, endometrin, and brethine
Warnings
It is not recommended to use Makena Auto Injector if you suffer from uncontrolled high blood pressure, abnormal vaginal bleeding, liver disease or cancer, jaundice due to your pregnancy, or if you've suffered from circulation issues such as a stroke or blood clot or breast cancer in the vagina, uterus, cervix, or uterus.
Before you take this drug
It is not recommended to treat this medication if you are sensitive to hydroxyprogesterone, the oil castor, or suffer from:
- Abnormal vaginal bleeding not associated with your pregnancies.
- Extreme or uncontrolled blood pressure.
- The liver, or cancer of the liver.
- The jaundice that is caused by pregnancy.
- A history of cancer in the breast, around the uterus, cervix, or vagina.
- An occurrence of a stroke, blood clot, or problems with circulation.
Hydroxyprogesterone has not been recommended to be used by anyone younger than 16 years of age.
Inform your doctor if you ever had:
- Preeclampsia or eclampsia due to pregnancy.
- kidney disease.
- High blood pressure and cardiovascular disease.
- Migraine headaches.
- Diabetes (in the case of you or an immediate relative).
- Epilepsy or any other seizures.
- Depression
- Asthma.
It's not clear if it will prevent any health issues in a newborn baby. Consult your physician regarding the risk your baby is at.
How to take Hydroxyprogesterone?
Hydroxyprogesterone is injected beneath either the skin or muscles. A doctor will administer this injection. The initial auto-injector, called Makena, is usually administered in the second trimester of pregnancy. The standard dosing schedule is one shot every week up to the 37th week, or until the birth of your baby. Follow the instructions of your doctor. Your doctor will examine your health regularly. Make sure you don't skip any scheduled appointments. Each woman must be under the supervision of a medical professional during her pregnancy.
What happens if I miss a dose?
Consult your physician for the best treatment. If you do not make an appointment to get the Makena Automated Injector.
What happens if I overdose?
For medical emergencies, seek emergency medical attention or contact the Poison Help line at 1-800-222-1222.
What should I be avoided?
Follow the doctor's advice regarding any restrictions on your food, drink, or activity.
Interaction with other drugs
Other medications may also alter hydroxyprogesterone levels, such as prescription and over-the-counter medicines, vitamins, and herbal products. Discuss with your doctor all the medicines you are currently taking and any medications you begin or stop taking.
