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Alogliptin

Generic Name: Alogliptin [AL-oh GLIP-tin]
Name of the Brand: Nesina
Dosage Format: oral tablet (12.5 mg, 25 mg, 6.25 mg)
Drug Class: Dipeptidyl peptidase 4 inhibitors

What is Alogliptin?

Alogliptin is used in conjunction with exercise and diet to increase blood sugar control in adults suffering from diabetes mellitus type 2. diabetic mellitus. Alogliptin isn't used to treat type 1 diabetes.

Alogliptin can be employed in conjunction with diabetes medication.Alogliptin is also employed for other purposes that are not covered in this medication guideline.

Side effects of Alogliptin

Seek medical attention immediately when you are experiencing symptoms warning signs of an allergic response (hives and breathing problems or swelling of your throat or face) or severe skin reactions (fever and burning eyes, sore throat, and skin irritation, as well as an ailment that is purple or red that blisters and peels).

Stop taking alogliptin and consult your doctor immediately if you are suffering from pancreatitis symptoms such as intense stomach pain extending into the back of your body, sickness or vomiting, weight loss, or rapid heartbeats.

Alogliptin could cause severe adverse effects. Contact your doctor immediately if you suffer from:

  • Persistent or severe joint pain;
  • Heart issues heart problems: breathlessness (even when lying down) rapid weight increase and swelling (especially on your legs, feet, or midsection);
  • Liver issues: nausea, stomach pain, fatigue, nausea, weight loss, black stools, dark urine, jaundice (yellowing of the eyes or skin)
  • A severe autoimmune reaction is an extreme autoimmune reaction resulting in itching and blisters, as well as the breakdown of the skin's outer layer.

Common adverse effects of alogliptin could include:

  • Headache
  • Cold symptoms like sinus pain, stuffy nose, and sore throat.

This isn't a complete list of possible side effects, and other effects may also be present. Contact your doctor to seek medical advice on the effects. You may report any adverse reactions to the FDA at 1-800-FDA-1088.

Warnings

Alogliptin may have serious adverse reactions in your pancreas and heart, especially if you've previously experienced similar issues or have renal or liver disease.

Get in touch with your doctor as soon as possible when you experience symptoms of pancreatitis—severe discomfort in your stomach that is spreading into your back—or indications for heart problems—shortness of breath when lying down, swelling, or weight gain in your feet or legs.

Alogliptin isn't a treatment for type 1 diabetes.

Before you Take this Drug

It is not recommended to use this medicine if you are sensitive to alogliptin or if you suffer from ketoacidosis as a diabetic (call your physician to seek treatment).

Inform your doctor if you have ever suffered from:

  • liver disease;
  • Heart disease;
  • Renal disease (or if you're taking dialysis);
  • Pancreatitis;
  • Gallstones
  • Alcoholism.

Follow the instructions of your physician about taking this medication when you are pregnant or get pregnant. Controlling diabetes is crucial during pregnancy, and being diagnosed with high blood sugar levels can cause problems for pregnant mothers as well as the baby.

It might not be safe to breastfeed while taking this medication. Talk to your doctor about any risks.Alogliptin is not a drug that has been approved to be used by anyone younger than 18 years of age.

How to Take Alogliptin?

Follow the directions on the prescription label and go through all medication guides or instructions. The doctor might change your dosage. Follow the medication exactly as prescribed.Alogliptin can be taken along with or even without following the instructions of your doctor.The blood sugar level of your body will have to be regularly checked, and you might require additional blood tests at the doctor's office.

There is a possibility that you are suffering from lower levels of blood sugar (hypoglycemia) and experiencing extreme hunger, dizziness, anger, or anxiety. It can also make you feel confused, scared, or shakey. To manage hypoglycemia, consume or drink rapid-acting sources of sugar (fruit juice crackers, hard candy raisins, apricots, or sugar-free soda).

Your physician may recommend a glucagon injection kit if you suffer from severe hypoglycemia. Make sure that your family members or your closest friends know how to administer the injection in an emergency.The levels of blood sugar may be impacted by illness, stress, surgery, drinking alcohol, exercise, or avoiding meals. Talk to your doctor before altering your dosage or medication schedule.

Alogliptin is just one component of a treatment programme that may include exercise, diet, control of weight, blood sugar tests, and medical treatment. Follow your doctor's advice carefully.Maintain at room temperature and free of heat, moisture, and light.

Details on Dosage

Usual Adult Dose for Diabetes Type 2:

The usual dosage is 25 mg taken orally, once a day.

Comments If used together with insulin or insulin secretagogues, such as sulfonylureas, lower doses of insulin or insulin secretagogues might be needed to reduce the risk of hypoglycemia.

It is used as an addition to exercise and diet to increase glycemic control in adult patients with type 2 diabetes mellitus. It can be administered as a single therapy or as part of a therapy combination.

What Happens If I Miss a Dose?

It is important to take your medication in the shortest time possible. However, do not take your missed dose if it's nearing the time to take the next dose. Don't take two doses at once.

What Happens If I Overdose?

You should seek medical attention in an emergency or contact the Poison Helpline at 1-800-222-1222 for help. There are signs of low blood sugar like intense weakening, blurred vision, sweating, difficulties speaking, tremors, stomach pain, confusion, and seizures (convulsions).

What Should be Avoided?

Beware of drinking alcohol.

Interaction with Other Drugs

Other medications may enhance or diminish the effects of alogliptin to lower blood sugar. This includes prescription and over-the-counter medicine, vitamins, and herbal remedies. Inform your doctor about the medicines you are currently taking and any medications you