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Generic name: Imiquimod topical [i-MI-kwi-mod-TOP-ik-al]
Classification of drugs: Topical anti-infectives, topical antineoplastics

What is Zyclara?

Zyclara is an immune-response modifier.Zyclara cream can be a prescribed medication for treating the condition known as actinic keratosis (a disease caused by excessive exposure to sunlight) on the scalp and face of adult patients who are more than 18 years old.

Zyclara cream also serves to treat warts of the genital area that are visible on the exterior of the body in adults and children aged twelve or older. This cream is not an effective treatment for genital warts.


If you take too much Zyclara or take it for a long time, it increases the chance of a serious skin reaction. Follow your doctor's advice.Avoid using Zyclara cream on areas with damaged, broken, or burned skin. You must wait until the skin condition has been treated before applying this cream.

Before you use Zyclara cream, inform your physician if you suffer from an immune system that is weak or an autoimmune disorder (graft-versus-host disease) or if you recently had an organ transplant such as bone marrow or cord blood donation.

In treating genital warts on the vagina, try not to apply it to your sensitive vaginal tissue. It could cause vaginal irritation or swelling, as well as painful urinary tract infections. Do not expose yourself to sunlight or a tanning bed. Imiquimod could cause sunburn more quickly. Make sure you wear protective attire and apply sunblock (SPF 30 or greater) whenever you're outside.

Zyclara ceam isn't an effective treatment for warts on the genital area, and it is not able to stop spreading the condition to others via vaginal, oral, or oral sexual sex. There is a chance that you will be able to develop new lesions as you use this medication. For the best results, you should continue applying the medication for the full time recommended by your doctor.

Zyclara cream does not provide protection against sexually transmitted infections like gonorrhea, chlamydia, herpes, HIV, or syphilis. Trichomoniasis.

If you're treating your rectal or genital areas using Zyclara, you should refrain from sexual activity when the medication is on your skin. Zyclara could weaken the material condoms and diaphragms are constructed from. If you utilize diaphragms or condoms for birth control, these products may fail if the rubber becomes weak, and a pregnancy that is not planned could be the result.

Similar/related drugs

Diclofenac topical, fluorouracil topical, imiquimod topical, Santyl, Efudex, Collagenase Santyl, and Aldara

Before you take this drug

Don't take Zyclara to treat genital warts in children younger than twelve years of age. Other uses for this medication are intended for adults older than 18.

To be sure Zyclara is suitable for you, inform your doctor if you previously had:

  • A weak immune system or autoimmune disorder;
  • A sunburn or any other skin issues;
  • Graft-versus-host disease.

If you're treating the rectal or genital area, do not engage in sexual activity when the medication is on your skin. Zyclara cream may cause diaphragms or rubber condoms to become weaker, which may rupture during sexual activity and result in an unwanted pregnancy.

Consult your physician if you are breastfeeding or pregnant.

How to take Zyclara?

Utilize Zyclara precisely as directed by your physician. Follow the directions on the label of your prescription, and make sure you read the medication's instructions or guides on sheets.Do not chew it. The topical medication is intended to be used only on the skin.

If you take too much Zyclara or apply it for a prolonged period, you could increase the risk of developing severe skin reactions. Don't use two different imiq topical formulations within the same treatment area.

Take note of and follow the instructions for use that come along with your medicine. Talk to your pharmacist or doctor for clarification if you are unsure of the instructions.Cleanse your hands before or after you apply Zyclara. Wash the skin to be treated and let it dry for a minimum of 10 minutes prior to applying the treatment.

Apply the cream in an even layer and rub it in thoroughly. Apply the cream at night and allow the cream to remain on for up to 8 hours. The next day, wash the skin using water and mild soap. Don't cover the skin with any form of bandaging made of plastic (you could make use of cloths made of cotton). Use only cotton underwear for treating warts of the genital region.

How often and for how long you take Zyclara will depend on the condition you're treating.

Actinic keratosis:

  • Use every day for two weeks, then for two weeks with no treatment.

Genital warts:

  • Repeat each day for up to 8 weeks.

Make sure to take this medication for the prescribed length of time, even if symptoms improve quickly.Zyclara isn't a solution for warts that are genital. It is possible to spread the disease to others via vaginal, anal, or oral sexual contact. There is also the possibility of developing new lesions while you are being treated.Contact your physician to discuss your condition if the one you're treating with Zyclara doesn't improve or becomes worse.

Your physician may advise you to discontinue using Zyclara for a period of time in the event of an allergic reaction to the medication. Even if it is the case that you missed a few doses, don't include time in the total amount of time you take this medication (2 weeks for keratitis causing actinic, 8 weeks for warts on the genital area).

Keep at ambient temperature. Don't freeze. Keep your pump at an angle. Make sure to keep each pack unopened until you are prepared to use it.

Do I be concerned if I miss a dose?

Don't miss the dose you missed, and take your next dose at the normal time. Don't take two doses at once.

What will happen if I take excessively?

For medical emergencies, seek emergency medical attention or contact the Poison Help Line toll-free at 1-800-222-1222.

The symptoms of an overdose can include extreme itching, being lightheaded, or fainting.

What should be avoided?

Do not swim or take a shower or bath during the time that the medicine is applied to your skin.Do not use Zyclara on wounds that are open or on skin that hasn't yet healed after surgery or other medical treatments.

Beware of getting this medicine into your nose, eyes, mouth, vagina, or rectum. If contact occurs, clean with water.Avoid exposure to the sun and tanning beds. Imiquimod may cause sunburn more quickly. Make sure you wear protective attire and sunblock (SPF 30 or greater) whenever you're outside.

Zyclara is not a protection from sexually transmitted illnesses, which include genital warts, chlamydia, gonorrhea, herpes, HIV, syphilis, and trichomoniasis. Discuss with your doctor safe practices for sex.Use Zyclara only to treat any illness that hasn't been examined by your physician. Avoid sharing this medication with anyone else, even if they suffer from similar symptoms to yours.

Side effects of Zyclara

Take immediate medical attention. If you show symptoms of an allergic reaction (Zyclara): hives, breathing problems, or swelling of your lips, face, and throat,

Rinse off the medication and contact your doctor at the earliest opportunity if you notice an extreme skin reaction like severe burning, itching, oozing, and bleeding, or any skin reactions where the medication was sprayed.

In treating warts of the genital area on the inside of your vagina, if you experience extreme swelling or problems with urination, discontinue Zyclara and consult your physician now.Contact your doctor immediately if you are suffering from:

  • Flu-like symptoms like chills, fever, nausea, fatigue, body aches, and swelling of the glands
  • The area where you took this medicine
  • Manifestations of the herpes virus (shingles): sores or blisters, itching, burning pain, tingling, and the appearance of a rash on your face or the torso.

Common Zyclara adverse effects could include:

  • Minor skin irritation, pain, and redness. Dryness, small skin irritation, flaking, scabbing, scaling, crusting, or swelling in the area where the medication was applied.
  • Modifications in the appearance of the treated skin (may change in the color of treated skin)
  • Headache;
  • Tiredness;

Interaction with other drugs

Skin care products will not be affected by any other medications that you are taking. However, there are many drugs that interfere with each other. Be sure to inform your healthcare professionals about all medications you are taking, which includes medications that are prescribed and available over the counter, vitamins, and herbal remedies.